(Q34054054)

30 July 2017

MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2. (English)

1 reference

30 July 2017

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

M P Gillam

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

D Nimbalkar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

L Sun

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

K Christov

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

D Ray

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

X Liu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

H Kiyokawa

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

language of work or name

English

0 references

publication date

17 February 2014

1 reference

30 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

932-938

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2014.3

5 June 2020

exact match

0 references

cites work

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1 reference

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Cdk2-null mice are resistant to ErbB-2-induced mammary tumorigenesis.

28 July 2018

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Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia

28 July 2018

1 reference

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Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo

28 July 2018

1 reference

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Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective

28 July 2018

1 reference

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Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus

28 July 2018

1 reference

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Global expression profiling of murine MEN1-associated tumors reveals a regulatory role for menin in transcription, cell cycle and chromatin remodelling.

28 July 2018

1 reference

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Cell cycle kinases in cancer

28 July 2018

1 reference

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Requirement for CDK4 kinase function in breast cancer

28 July 2018

1 reference

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Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c

28 July 2018

1 reference

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A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation

28 July 2018

1 reference

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Molecular genetics of multiple endocrine neoplasia types 1 and 2.

28 July 2018

1 reference

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Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

28 July 2018

1 reference

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Living with or without cyclins and cyclin-dependent kinases

28 July 2018

1 reference

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Cdk4 is indispensable for postnatal proliferation of the anterior pituitary.

28 July 2018

1 reference

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Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

28 July 2018

1 reference

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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

28 July 2018

1 reference

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Cdk2 knockout mice are viable

28 July 2018

1 reference

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Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number

28 July 2018

1 reference

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A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

28 July 2018

1 reference

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The Pezcoller lecture: cancer cell cycles revisited

28 July 2018

1 reference

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Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity

28 July 2018

1 reference

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

28 July 2018

1 reference

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

28 July 2018

1 reference

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

28 July 2018

1 reference

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CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

28 July 2018

1 reference

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

28 July 2018

1 reference

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

28 July 2018

1 reference

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

28 July 2018

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Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

28 July 2018

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The cyclin-dependent kinase inhibitors p27Kip1 and p21Cip1 cooperate to restrict proliferative life span in differentiating ovarian cells

28 July 2018

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Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity

21 January 2018

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Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.

21 January 2018

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Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice

21 January 2018

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IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

21 January 2018

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MEN1 missense mutations impair sensitization to apoptosis induced by wild-type menin in endocrine pancreatic tumor cells

21 January 2018

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Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941]

21 January 2018

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Genetic evidence for functional dependency of p18Ink4c on Cdk4.

21 January 2018

1 reference

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Cdc2-cyclin E complexes regulate the G1/S phase transition

21 January 2018

1 reference

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Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability.

21 January 2018

1 reference

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The multiple endocrine neoplasia type 1 gene product, menin, inhibits insulin production in rat insulinoma cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135037

Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1

28 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.3

A role of FRK in regulation of embryonal pancreatic beta cell formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.3

Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.3

Somatic mutations in MEN type 1 tumors, consistent with the Knudson "two-hit" hypothesis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24531709

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531709%20AND%20SRC:MED&resulttype=core&format=json