(Q34063560)

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Voreloxin, a first-in-class anticancer quinolone derivative, acts synergistically with cytarabine in vitro and induces bone marrow aplasia in vivo

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Europe PubMed Central

PubMed publication ID

30 July 2017

Voreloxin, a first-in-class anticancer quinolone derivative, acts synergistically with cytarabine in vitro and induces bone marrow aplasia in vivo (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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author name string

Caroline D Scatena

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Jeffrey L Kumer

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Jennifer P Arbitrario

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Anthony R Howlett

4

1 reference

Europe PubMed Central

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30 July 2017

Rachael E Hawtin

5

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Europe PubMed Central

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30 July 2017

Judith A Fox

6

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Europe PubMed Central

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30 July 2017

Jeffrey A Silverman

7

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Europe PubMed Central

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30 July 2017

language of work or name

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publication date

8 January 2010

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30 July 2017

Cancer Chemotherapy and Pharmacology

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Europe PubMed Central

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30 July 2017

66

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Europe PubMed Central

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30 July 2017

5

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Europe PubMed Central

PubMed publication ID

30 July 2017

881-888

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Europe PubMed Central

PubMed publication ID

30 July 2017

Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Voreloxin, a first-in-class anticancer quinolone derivative, in relapsed/refractory solid tumors: a report on two dosing schedules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

1 reference

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5 July 2018

Evaluating response to antineoplastic drug combinations in tissue culture models.

1 reference

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5 July 2018

How do stem cells find their way home?

1 reference

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5 July 2018

Drug therapy for acute myeloid leukemia

1 reference

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5 July 2018

In vitro studies of a FLT3 inhibitor combined with chemotherapy: sequence of administration is important to achieve synergistic cytotoxic effects

1 reference

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5 July 2018

Structure and function of bone marrow hemopoiesis: mechanisms of response to ionizing radiation exposure

1 reference

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5 July 2018

The roles of FLT3 in hematopoiesis and leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Cellular resistance to anthracyclines.

1 reference

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5 July 2018

Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Clinical relevance of P-glycoprotein expression in de novo acute myeloid leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Chemotherapy of leukemia in mice, rats, and humans relating time of humoral stimulation, tumor growth, and clinical response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Cardiotoxicity and comparative pharmacokinetics of six anthracyclines in the rabbit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

The pharmacokinetics of daunomycin in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Inhibitory effect of 1-beta-D-arabinofuranosylthymine 5'-triphosphate and 1-beta-D-arabinofuranosylcytosine 5'-triphosphate on DNA polymerases from murine cells and oncornavirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

5 July 2018

Metabolism of (+)-1,4-dihydro-7-(trans-3-methoxy-4-methylamino-1-pyrrolidinyl)-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid (voreloxin; formerly SNS-595), a novel replication-dependent DNA-damaging agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

28 October 2018

Evaluation of combination chemotherapy: integration of nonlinear regression, curve shift, isobologram, and combination index analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921053

28 October 2018

A study of the mechanisms of cytotoxicity of Ara-C on three human leukemic cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of DNA breakage in cytotoxicity of doxorubicin, 9-deoxydoxorubicin, and 4-demethyl-6-deoxydoxorubicin in murine leukemia P388 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Equivalent survival for sibling and unrelated donor allogeneic stem cell transplantation for acute myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced-intensity conditioning for unrelated donor hematopoietic stem cell transplantation as treatment for myeloid malignancies in patients older than 55 years

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of cytotoxicity with incorporation of ara-C into DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of 1-beta-D-arabinofuranosylcytosine incorporation on eukaryotic DNA template function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemic cell and plasma daunomycin concentrations after bolus injection and 72 h infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of inhibition of DNA ligase in Ara-C treated cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00280-009-1234-Z

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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