(Q34064442)

English

Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus (English)

1 reference

Europe PubMed Central

30 July 2017

0 references

Alzheimer's disease

0 references

0 references

author name string

Jaya R P Prasanthi

1

1 reference

Europe PubMed Central

30 July 2017

Tyler Larson

2

1 reference

Europe PubMed Central

30 July 2017

Jared Schommer

3

1 reference

Europe PubMed Central

30 July 2017

Othman Ghribi

4

1 reference

Europe PubMed Central

30 July 2017

language of work or name

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publication date

14 October 2011

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

6

1 reference

Europe PubMed Central

30 July 2017

10

1 reference

Europe PubMed Central

30 July 2017

e26420

1 reference

Europe PubMed Central

30 July 2017

copyright license

Creative Commons Attribution 4.0 International

14 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

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1 reference

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Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet

1 reference

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Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices

1 reference

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Alzheimer's Disease

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Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.

1 reference

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28 July 2018

Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells

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Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

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28 July 2018

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

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Oxysterols, cholesterol homeostasis, and Alzheimer disease

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Endoplasmic reticulum stress and neurodegeneration in rats neonatally infected with borna disease virus

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Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease

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28 July 2018

Molecular control of vertebrate iron homeostasis by iron regulatory proteins

1 reference

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28 July 2018

Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor

1 reference

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28 July 2018

Endoplasmic reticulum stress: cell life and death decisions.

1 reference

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Role of glutathione in intracellular amyloid-alpha precursor protein/carboxy-terminal fragment aggregation and associated cytotoxicity

1 reference

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28 July 2018

Alzheimer's disease: Abeta, tau and synaptic dysfunction

1 reference

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28 July 2018

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 July 2018

Metal and inflammatory targets for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Brain iron deposition and the free radical-mitochondrial theory of ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 July 2018

Increased apoptotic cell death in sporadic and genetic Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 July 2018

Roles of CHOP/GADD153 in endoplasmic reticulum stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 July 2018

Dehydroepiandrosterone reduces expression and activity of BACE in NT2 neurons exposed to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 July 2018

Iron regulatory proteins as NO signal transducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 July 2018

The labile iron pool: characterization, measurement, and participation in cellular processes(1).

1 reference

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28 July 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

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Iron and neurodegenerative disorders

1 reference

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The unfolded protein response and Alzheimer's disease

1 reference

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28 July 2018

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

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Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease

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Determination of the chelatable iron pool of single intact cells by laser scanning microscopy

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Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins

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1 reference

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Conformational disease

1 reference

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28 July 2018

Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

1 reference

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28 July 2018

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1 reference

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28 July 2018

Defective protein folding as a basis of human disease

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Regulating the fate of mRNA: the control of cellular iron metabolism

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Hydrogen peroxide mediates amyloid beta protein toxicity

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Radical AGEing in Alzheimer's disease

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28 July 2018

Iron(II) is a modulator of ryanodine-sensitive calcium channels of cardiac muscle sarcoplasmic reticulum

1 reference

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Ferritin: isolation of aluminum-ferritin complex from brain

1 reference

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The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene

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28 July 2018

Regional brain trace-element studies in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 July 2018

Regulation of ferritin and transferrin receptor mRNAs

1 reference

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1 reference

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Transferrin receptors of rat and human brain and cerebral microvessels and their status in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 July 2018

Protein oxidation and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

1 reference

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Iron: a new target for pharmacological intervention in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Redox metals in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Ironing out Parkinson's disease: is therapeutic treatment with iron chelators a real possibility?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Endoplasmic reticulum signaling as a determinant of recombinant protein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

28 October 2018

Oxidative stress increases expression and activity of BACE in NT2 neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Abnormal localization of iron regulatory protein in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3194795

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Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22046282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22046282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of transcription inhibitors on the iron-dependent degradation of transferrin receptor mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/22046282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic crosstalk between the endoplasmic reticulum and mitochondria controlled by Bcl-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22046282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bip/GRP78-induced production of cytokines and uptake of amyloid-beta(1-42) peptide in microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22046282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22046282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron up-modulates the expression of transferrin receptors during monocyte-macrophage maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22046282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0026420

1 reference

Europe PubMed Central

30 July 2017

2011PLoSO...626420P

0 references

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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