(Q34067223)

30 July 2017

Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes (English)

1 reference

30 July 2017

0 references

Jay A Grobler

1

1 reference

30 July 2017

Kara Stillmock

2

1 reference

30 July 2017

Binghua Hu

3

1 reference

30 July 2017

Marc Witmer

4

1 reference

30 July 2017

Peter Felock

5

1 reference

30 July 2017

Amy S Espeseth

6

1 reference

30 July 2017

Abigail Wolfe

7

1 reference

30 July 2017

Melissa Egbertson

8

1 reference

30 July 2017

Michele Bourgeois

9

1 reference

30 July 2017

Jeffrey Melamed

10

1 reference

30 July 2017

John S Wai

11

1 reference

30 July 2017

Steve Young

12

1 reference

30 July 2017

Joseph Vacca

13

1 reference

30 July 2017

Daria J Hazuda

14

1 reference

30 July 2017

language of work or name

English

0 references

publication date

7 May 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

1 reference

30 July 2017

99

1 reference

30 July 2017

10

1 reference

30 July 2017

6661-6666

1 reference

Effect of HIV integrase inhibitors on the RAG1/2 recombinase

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Three-dimensional structure of the Tn5 synaptic complex transposition intermediate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Retroviral DNA integration.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Type II restriction endonucleases: structural, functional and evolutionary relationships

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Crystal structures of catalytic core domains of retroviral integrases and role of divalent cations in enzymatic activity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

DNA polymerases: structural diversity and common mechanisms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Molecular mechanisms in retrovirus DNA integration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Inhibitors of HIV-1 replication [corrected; erratum to be published] that inhibit HIV integrase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

The metal ion-induced cooperative binding of HIV-1 integrase to DNA exhibits a marked preference for Mn(II) rather than Mg(II).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

A novel assay for the DNA strand-transfer reaction of HIV-1 integrase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Human immunodeficiency virus type 1 integrase: effects of mutations on viral ability to integrate, direct viral gene expression from unintegrated viral DNA templates, and sustain viral propagation in primary cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Substrate specificity of recombinant human immunodeficiency virus integrase protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124459

Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA.

28 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.092056199

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.092056199

Determinants of ribose specificity in RNA polymerization: effects of Mn2+ and deoxynucleoside monophosphate incorporation into transcripts

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11997448

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

All three residues of the Tn 10 transposase DDE catalytic triad function in divalent metal ion binding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11997448

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.092056199

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference