(Q34070380)

English

Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

author name string

Robbie L McLeod

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Deen B Tulshian

2

1 reference

Europe PubMed Central

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30 July 2017

Donald C Bolser

3

1 reference

Europe PubMed Central

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30 July 2017

Geoffrey B Varty

4

1 reference

Europe PubMed Central

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30 July 2017

Marco Baptista

5

1 reference

Europe PubMed Central

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30 July 2017

Xiomara Fernandez

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Leonard E Parra

7

1 reference

Europe PubMed Central

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30 July 2017

Jennifer C Zimmer

8

1 reference

Europe PubMed Central

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30 July 2017

Christine H Erickson

9

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Ginny D Ho

10

1 reference

Europe PubMed Central

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30 July 2017

Yanlin Jia

11

1 reference

Europe PubMed Central

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30 July 2017

Fay W Ng

12

1 reference

Europe PubMed Central

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30 July 2017

Walter Korfmacher

13

1 reference

Europe PubMed Central

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30 July 2017

Xiaoying Xu

14

1 reference

Europe PubMed Central

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30 July 2017

John Veals

15

1 reference

Europe PubMed Central

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30 July 2017

April Smith-Torhan

16

1 reference

Europe PubMed Central

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30 July 2017

Samuel Wainhaus

17

1 reference

Europe PubMed Central

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30 July 2017

Ahmad B Fawzi

18

1 reference

Europe PubMed Central

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30 July 2017

Theodore M Austin

19

1 reference

Europe PubMed Central

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30 July 2017

Margaret van Heek

20

1 reference

Europe PubMed Central

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30 July 2017

John A Hey

21

1 reference

Europe PubMed Central

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30 July 2017

language of work or name

0 references

publication date

16 December 2009

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

European Journal of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

630

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1-3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

112-120

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Current applications of liquid chromatography/mass spectrometry in pharmaceutical discovery after a decade of innovation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Unexpected infant deaths associated with use of cough and cold medications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Adverse events from cough and cold medications in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Encoding of the cough reflex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Codeine and cough: an ineffective gold standard

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Principles and applications of LC-MS in new drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

The nociceptin/orphanin FQ/NOP receptor system as a target for treatment of alcohol abuse: a review of recent work in alcohol-preferring rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Antitussive effect of nociceptin/orphanin FQ in experimental cough models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Nociceptin/orphanin FQ inhibits capsaicin-induced guinea-pig airway contraction through an inward-rectifier potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Nociceptin inhibits cough in the guinea-pig by activation of ORL(1) receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Neurohumoral effects of orphanin FQ/nociceptin: relevance to cardiovascular and renal function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Nociceptin and neurotransmitter release in the periphery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Gastroesophageal reflux and chronic cough

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Pharmacology of nociceptin and its receptor: a novel therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Antitussive action of antihistamines is independent of sedative and ventilation activity in the guinea pig.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Nociceptin activation of the human ORL1 receptor expressed in Chinese hamster ovary cells: functional homology with opioid receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Structure-activity relationship studies on the novel neuropeptide orphanin FQ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Cocaine-induced place preference conditioning: lack of effects of neuroleptics and 6-hydroxydopamine lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Angiotensin-converting enzyme inhibitors and their influence on inflammation, bronchial reactivity and cough. A research review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

5 July 2018

Effect of a novel NOP receptor agonist (SCH 225288) on guinea pig irritant-evoked, feline mechanically induced and canine infectious tracheobronchitis cough

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

Identification of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the management of cough and anxiety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

Effect of nociceptin in acid-evoked cough and airway sensory nerve activation in guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

Orphanin FQ/nociceptin blocks methamphetamine place preference in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

National Ambulatory Medical Care Survey: 2000 summary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

Chronic cough due to gastroesophageal reflux disease: efficacy of antireflux surgery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

Antitussive action of nociceptin in the cat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

Antitussive effects of GABAB agonists in the cat and guinea-pig

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

Conditioned place preference using opiate and stimulant drugs: a meta-analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2922759

28 October 2018

Citing serious risks, FDA recommends no cold and cough medicines for infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/20006596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HPLC-MS/MS in drug metabolism and pharmacokinetic screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/20006596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro characterization of J-113397, a non-peptide nociceptin/orphanin FQ receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/20006596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin inhibits capsaicin-induced bronchoconstriction in isolated guinea pig lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/20006596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity of the cough reflex in patients with chronic cough

1 reference

https://pubmed.ncbi.nlm.nih.gov/20006596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EJPHAR.2009.12.003

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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