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Has the outlook improved for amifostine as a clinical radioprotector?
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Has the outlook improved for amifostine as a clinical radioprotector?
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
author
Cai Grau
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
author name string
J C Lindegaard
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
publication date
1 November 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
published in
Radiotherapy and Oncology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
57
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
page(s)
113-118
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
cites work
Salivary gland protection by amifostine in high-dose radioiodine treatment: results of a double-blind placebo-controlled study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radioprotection of salivary glands by S-2-(3-aminopropylamino)-ethylphosphorothioic (amifostine) obtained in a rabbit animal model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A randomized study of very accelerated radiotherapy with and without amifostine in head and neck squamous cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective cytoprotection with amifostine in concurrent radiochemotherapy for head and neck cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection of Normal Tissue from the Cytotoxic Effects of Chemotherapy and Radiation by Amifostine: Clinical Experiences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor blood flow changes induced by chemical modifiers of radiation response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of WR 2721 on the efficacy of radiotherapy and chemotherapy of murine tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radioprotection of mouse skin by WR-2721: The critical influence of oxygen tension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is the outlook grey for WR-2721 as a clinical radioprotector?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radioprotection by WR-2721 in vitro at low oxygen tensions: Implications for its mechanisms of action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radiosensitisation and radioprotection by BSO and WR-2721: the role of oxygenation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
American Society of Clinical Oncology clinical practice guidelines for the use of chemotherapy and radiotherapy protectants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sulfhydryl containing compounds WR-2721 and glutathione as radio- and chemoprotective agents. A review, indications for use and prospects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of radiation with or without WR-2721 in advanced rectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of Radioprotective Drugs on the Therapeutic Ratio for a Mouse Tumor System
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of WR 2721 on radiation response of canine soft tissue sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preliminary results of a pilot study using WR-2721 before fractionated irradiation of the head and neck to reduce salivary gland dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radioprotection combined with hypoxic sensitization during radiotherapy of a solid murine tumor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protective effects of WR-2721 against radiation-induced injury of murine gut, testis, lung, and lung tumor nodules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The modification of melphalan toxicity in tumor bearing mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid (WR2721)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical study of radioprotective effects of amifostine (YM-08310, WR-2721) on long-term outcome for patients with cervical cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dephosphorylation of WR-2721 with mouse tissue homogenates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cysteine Protection against X Irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radioprotection of mouse skin vasculature and the RIF-1 fibrosarcoma by WR-2721
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection of Normal Tissues from the Cytotoxic Effects of Chemotherapy and Radiation by Amifostine (WR-2721): Preclinical Aspects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Design and interpretation of clinical trials that evaluate agents that may offer protection from the toxic effects of cancer chemotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radioprotection of tumor and normal tissues by thiophosphate compounds
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radioprotection of Normal Tissues against Gamma Rays and Cyclotron Neutrons with WR-2721: LD 50 Studies and 35 S-WR-2721 Biodistribution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of X ray dose levels on normal tissue radioprotection by WR-2721
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Experimental radiotherapy with WR-2721 and misonidazole
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of misonidazole and WR-2721—II. Modification of tumour radiosensitization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fractionation studies with WR-2721: normal tissues and tumour
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thiol WR-1065 and disulphide WR-33278, two metabolites of the drug ethyol (WR-2721), protect DNA against fast neutron-induced strand breakage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Effect of S-2-(3-Aminopropylamino)ethylphosphorothioic Acid (WR-2721) on Intestinal Crypt Survival: II. Fission Neutrons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Target cell and mode of radiation injury in rhesus salivary glands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radiation apoptosis of serous acinar cells of salivary and lacrimal glands.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The oxygen dependence of protection by aminothiols: Implications for normal tissues and solid tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of the modulating agent WR2721 on myelotoxicity and antitumour activity in carboplatin-treated mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modification by WR 2721 of the response to chemotherapy of tumours and normal tissues in the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetics of WR-1065 in mouse tissue following treatment with WR-2721
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential radioprotection of euoxic and hypoxic mouse mammary tumors by a thiophosphate compound.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prediction of the Effective Radioprotective Dose of WR-2721 in Humans through an Interspecies Tissue Distribution Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor sensitization and protection: Influence of stromal injury on estimates of dose modification
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radiotherapy of experimental lung tumors in the presence and absence of a radioprotective drug, S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protective drugs in cancer therapy: Optimal clinical testing and future directions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy testing of WR-2721 in Great Britain or everything is black and white at the gray lab
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combined Use of Radioprotective and Radiosensitizing Drugs in Experimental Radiotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variation in normal tissue responsiveness to WR-2721
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-8140%2800%2900235-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0167-8140(00)00235-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
11054513
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11054513
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11054513%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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