(Q34074137)

30 July 2017

7 references

21 March 2019

3 August 2019

9 August 2019

12 October 2019

18 October 2019

20 November 2019

12 September 2020

Th17-related cytokines: new players in the control of chronic intestinal inflammation (English)

1 reference

30 July 2017

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21 March 2019

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20 November 2019

12 September 2020

7 references

21 March 2019

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12 October 2019

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12 September 2020

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3 August 2019

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9 August 2019

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12 October 2019

hemic and immune systems

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18 October 2019

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20 November 2019

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12 September 2020

Ivan Monteleone

1

1 reference

30 July 2017

Francesco Pallone

series ordinal

2

1 reference

30 July 2017

Giovanni Monteleone

series ordinal

3

1 reference

30 July 2017

language of work or name

English

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publication date

15 November 2011

8 references

30 July 2017

21 March 2019

3 August 2019

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12 October 2019

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20 November 2019

12 September 2020

8 references

30 July 2017

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9

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page(s)

122

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Creative Commons Attribution 2.0 Generic

30 July 2017

copyright license

7 references

21 March 2019

3 August 2019

9 August 2019

12 October 2019

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20 November 2019

on focus list of Wikimedia project

12 September 2020

copyright status

copyrighted

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ScienceSource

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exact match

https://scigraph.springernature.com/pub.10.1186/1741-7015-9-122

0 references

cites work

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Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

28 July 2018

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The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

28 July 2018

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Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

28 July 2018

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T regulatory cells maintain intestinal homeostasis by suppressing γδ T cells.

28 July 2018

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γδ T cells protect against lung fibrosis via IL-22.

28 July 2018

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Interleukin-23 drives intestinal inflammation through direct activity on T cells

28 July 2018

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TGF-beta induces IL-9 production from human Th17 cells.

28 July 2018

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Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

28 July 2018

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Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor.

28 July 2018

1 reference

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Inflammatory bowel disease

28 July 2018

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Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease

28 July 2018

1 reference

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The aryl hydrocarbon receptor in immunity

28 July 2018

1 reference

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Fontolizumab in moderate to severe Crohn's disease: a phase 2, randomized, double-blind, placebo-controlled, multiple-dose study

28 July 2018

1 reference

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Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity

28 July 2018

1 reference

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Developmental plasticity of Th17 and Treg cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

A protective function for interleukin 17A in T cell-mediated intestinal inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Late developmental plasticity in the T helper 17 lineage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Regulation of inflammatory responses by IL-17F

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Phenotypic and functional features of human Th17 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

The fundamental basis of inflammatory bowel disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Anti-interleukin-12 antibody for active Crohn's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Interleukin-17 family and IL-17 receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Increased expression of interleukin 17 in inflammatory bowel disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

The immunology of mucosal models of inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Claudins regulate the intestinal barrier in response to immune mediators

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Colitis-inducing potency of CD4+ T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis.

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Induction and effector functions of T(H)17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

IL-9 is a Th17-derived cytokine that limits pathogenic activity in organ-specific autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

The role of the novel Th17 cytokine IL-26 in intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Increased expression of CCL20 in human inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Regulation of gut inflammation and th17 cell response by interleukin-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Over-production of IFN-gamma and IL-12 in AhR-null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-9-122

A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3239315

IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration

28 October 2018

1 reference

12 December 2020

Critical role of IL-17 receptor signaling in acute TNBS-induced colitis

1 reference

12 December 2020

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes

1 reference

12 December 2020

A Functional Role for Interleukin-21 in Promoting the Synthesis of the T-Cell Chemoattractant, MIP-3α, by Gut Epithelial Cells

1 reference

12 December 2020

Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status

1 reference

12 December 2020

Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD

1 reference

12 December 2020

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

1 reference

12 December 2020

Effects of aryl hydrocarbon receptor signaling on the modulation of TH1/TH2 balance

1 reference

12 December 2020

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

1 reference

12 December 2020

Human Th17 cells comprise heterogeneous subsets including IFN-gamma-producing cells with distinct properties from the Th1 lineage

1 reference

12 December 2020

Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases

1 reference

12 December 2020

Identifiers

DOI

10.1186/1741-7015-9-122

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference