(Q34074254)

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Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3. (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

author name string

Xiaorong Zhu

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Lelio Orci

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Raymond Carroll

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Christina Norrbom

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Mariella Ravazzola

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Donald F Steiner

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

22 July 2002

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

99

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

10299-10304

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

1 reference

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5 July 2018

The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site

1 reference

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5 July 2018

The testicular germ-cell protease PC4 is also expressed in macrophage-like cells of the ovary

1 reference

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5 July 2018

Minireview: the glucagon-like peptides

1 reference

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5 July 2018

Translational regulation of proinsulin biosynthesis and proinsulin conversion in the pancreatic beta-cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Proteolytic processing in the secretory pathway

1 reference

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5 July 2018

Tissue-specific processing of cocaine- and amphetamine-regulated transcript peptides in the rat.

1 reference

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5 July 2018

Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

The post-translational processing and intracellular sorting of carboxypeptidase H in the islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Homology modelling of the catalytic domain of human furin. A model for the eukaryotic subtilisin-like proprotein convertases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Brief report: impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Direct identification of prohormone conversion site in insulin-secreting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Recognition of human insulin and proinsulin by monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Characterization of the two nonallelic genes encoding mouse preproinsulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Carboxypeptidase E

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Islet amyloid polypeptide. A new beta cell secretory product related to islet amyloid deposits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Preferential cleavage of des-31,32-proinsulin over intact proinsulin by the insulin secretory granule type II endopeptidase. Implication of a favored route for prohormone processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Preparation and characterization of plasma membrane-enriched fractions from rat pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

5 July 2018

Glucagon replacement via micro-osmotic pump corrects hypoglycemia and alpha-cell hyperplasia in prohormone convertase 2 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

28 October 2018

Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

28 October 2018

Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

28 October 2018

Gene expression of prohormone and proprotein convertases in the rat CNS: a comparative in situ hybridization analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

28 October 2018

Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124908

28 October 2018

Expression of two proopiomelanocortin mRNAs in the islets of Langerhans of neonatal rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12136131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular modeling of the substrate specificity of prohormone convertases SPC2 and SPC3

1 reference

https://pubmed.ncbi.nlm.nih.gov/12136131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

28 Methods for the assessment of peptide precursors. Studies on insulin biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12136131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Production and Characterization of Monoclonal Antibodies Specific for Human Proinsulin Using a Sensitive Microdot Assay Procedure*

1 reference

https://pubmed.ncbi.nlm.nih.gov/12136131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/12136131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of des(64,65)-human proinsulin in the rat. Evidence for the proteolytic processing to insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12136131

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.162352799

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2002PNAS...9910299Z

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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