(Q34074365)

30 July 2017

title

The rapid-onset dystonia parkinsonism mutation D923N of the Na+, K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site (English)

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30 July 2017

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parkinsonian syndrome

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Anja Pernille Einholm

1

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30 July 2017

Mads S Toustrup-Jensen

2

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30 July 2017

Rikke Holm

3

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30 July 2017

Jens Peter Andersen

4

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30 July 2017

Bente Vilsen

5

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30 July 2017

language of work or name

English

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publication date

24 June 2010

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30 July 2017

number of pages

10

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Journal of Biological Chemistry

inferred from page(s)

published in

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30 July 2017

volume

285

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30 July 2017

issue

34

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30 July 2017

page(s)

26245-26254

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Hyperpolarization-activated inward leakage currents caused by deletion or mutation of carboxy-terminal tyrosines of the Na+/K+-ATPase {alpha} subunit

30 July 2017

cites work

1 reference

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Altered Na+ transport after an intracellular alpha-subunit deletion reveals strict external sequential release of Na+ from the Na/K pump

5 July 2018

1 reference

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Rapid-onset dystonia-parkinsonism in a child with a novel atp1a3 gene mutation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Crystal structure of the sodium-potassium pump at 2.4 A resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

The C terminus of Na+,K+-ATPase controls Na+ affinity on both sides of the membrane through Arg935.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

How Ca2+-ATPase pumps ions across the sarcoplasmic reticulum membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Biochemical aspects of active transport

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Crystal structure of the sodium–potassium pump

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

The phenotypic spectrum of rapid-onset dystonia-parkinsonism (RDP) and mutations in the ATP1A3 gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

A third Na+-binding site in the sodium pump

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Mutations in the Na+/K+ -ATPase alpha3 gene ATP1A3 are associated with rapid-onset dystonia parkinsonism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Homology modeling of the cation binding sites of Na+K+-ATPase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Biochemistry of Na,K-ATPase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Structure-function relationships of Na(+), K(+), ATP, or Mg(2+) binding and energy transduction in Na,K-ATPase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Alanine scanning mutagenesis of oxygen-containing amino acids in the transmembrane region of the Na,K-ATPase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Mutation to the glutamate in the fourth membrane segment of Na+,K+-ATPase and Ca2+-ATPase affects cation binding from both sides of the membrane and destabilizes the occluded enzyme forms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Annual review prize lecture. 'All hands to the sodium pump'.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Substitutions of serine 775 in the alpha subunit of the Na,K-ATPase selectively disrupt K+ high affinity activation without affecting Na+ interaction.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Structure-function relationships in the Ca(2+)-ATPase of sarcoplasmic reticulum studied by use of the substrate analogue CrATP and site-directed mutagenesis. Comparison with the Na+,K(+)-ATPase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

ADP- and K+-sensitive phosphorylated intermediate of Na,K-ATPase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Comparison of the substrate dependence properties of the rat Na,K-ATPase alpha 1, alpha 2, and alpha 3 isoforms expressed in HeLa cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

Functional consequences of alterations to Pro328 and Leu332 located in the 4th transmembrane segment of the alpha-subunit of the rat kidney Na+,K(+)-ATPase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

A C-terminal mutation of ATP1A3 underscores the crucial role of sodium affinity in the pathophysiology of rapid-onset dystonia-parkinsonism

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Mutant Glu781-->Ala of the rat kidney Na+,K(+)-ATPase displays low cation affinity and catalyzes ATP hydrolysis at a high rate in the absence of potassium ions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Mutational effects on conformational changes of the dephospho- and phospho-forms of the Na+,K+-ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Importance of Glu(282) in transmembrane segment M3 of the Na(+),K(+)-ATPase for control of cation interaction and conformational changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Site-directed mutagenesis of the Na,K-ATPase: consequences of substitutions of negatively-charged amino acids localized in the transmembrane domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Thr-774 (transmembrane segment M5), Val-920 (M8), and Glu-954 (M9) are involved in Na+ transport, and Gln-923 (M8) is essential for Na,K-ATPase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Ion selectivity of the cytoplasmic binding sites of the Na,K-ATPase: II. Competition of various cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

The third sodium binding site of Na,K-ATPase is functionally linked to acidic pH-activated inward current.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Electrogenicity of Na,K- and H,K-ATPase activity and presence of a positively charged amino acid in the fifth transmembrane segment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Glutamate 779, an intramembrane carboxyl, is essential for monovalent cation binding by the Na,K-ATPase.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924038

External Na dependence of ouabain-sensitive ATP: ADP exchange initiated by photolysis of intracellular caged-ATP in human red cell ghosts

28 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.123976

Occlusion of Na+ by the Na,K-ATPase in the presence of oligomycin

21 January 2018

1 reference

12 December 2020

Two different phosphorylation-dephosphorylation cycles of Na,K-ATPase proteoliposomes accompanying Na+ transport in the absence of K+

1 reference

12 December 2020

Immunofluorescent localization of three Na,K-ATPase isozymes in the rat central nervous system: both neurons and glia can express more than one Na,K-ATPase

1 reference

12 December 2020

Fast kinetic analysis of conformational changes in mutants of the Ca(2+)-ATPase of sarcoplasmic reticulum

1 reference

12 December 2020

Microdetermination of inorganic phosphate, phospholipids, and total phosphate in biologic materials

1 reference

12 December 2020

Sodium-potassium-activated adenosine triphosphatase of Electrophorus electric organ. V. Phosphorylation by adenosine triphosphate-32P

1 reference

12 December 2020

Activation by adenosine triphosphate in the phosphorylation kinetics of sodium and potassium ion transport adenosine triphosphatase

1 reference

12 December 2020

Sodium pump-catalyzed sodium-sodium exchange associated with ATP hydrolysis

1 reference

12 December 2020

Amino acid substitutions in the rat Na+, K(+)-ATPase alpha 2-subunit alter the cation regulation of pump current expressed in HeLa cells

1 reference

12 December 2020

Evidence that Ser775 in the alpha subunit of the Na,K-ATPase is a residue in the cation binding pocket

1 reference

12 December 2020

Leucine 332 at the boundary between the fourth transmembrane segment and the cytoplasmic domain of Na+,K+-ATPase plays a pivotal role in the ion translocating conformational changes

1 reference

12 December 2020

Functional consequences of mutations in the transmembrane core region for cation translocation and energy transduction in the Na+,K(+)-ATPase and the SR Ca(2+)-ATPase

1 reference

12 December 2020

Contribution to Tl+, K+, and Na+ binding of Asn776, Ser775, Thr774, Thr772, and Tyr771 in cytoplasmic part of fifth transmembrane segment in alpha-subunit of renal Na,K-ATPase

1 reference

12 December 2020

Functional role of oxygen-containing residues in the fifth transmembrane segment of the Na,K-ATPase alpha subunit

1 reference

12 December 2020

Ion selectivity of the cytoplasmic binding sites of the Na,K-ATPase: I. Sodium binding is associated with a conformational rearrangement

1 reference

12 December 2020

Mutant Phe788 --> Leu of the Na+,K+-ATPase is inhibited by micromolar concentrations of potassium and exhibits high Na+-ATPase activity at low sodium concentrations

1 reference

12 December 2020

Importance of Leu99 in transmembrane segment M1 of the Na+, K+ -ATPase in the binding and occlusion of K+

1 reference

12 December 2020

Novel ATP1A3 mutation in a sporadic RDP patient with minimal benefit from deep brain stimulation

1 reference

12 December 2020

[123I]-FP-CIT and [99mTc]-HMPAO single photon emission computed tomography in a new sporadic case of rapid-onset dystonia-parkinsonism

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.123976

1 reference

30 July 2017

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30 July 2017

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