(Q34074520)

30 July 2017

Neurotoxic mutants of the prion protein induce spontaneous ionic currents in cultured cells (English)

1 reference

30 July 2017

0 references

1 reference

Isaac H Solomon

1

1 reference

30 July 2017

James E Huettner

series ordinal

2

1 reference

30 July 2017

David A Harris

series ordinal

3

1 reference

30 July 2017

language of work or name

English

0 references

publication date

23 June 2010

1 reference

Journal of Biological Chemistry

30 July 2017

1 reference

30 July 2017

285

1 reference

30 July 2017

34

1 reference

30 July 2017

26719-26726

1 reference

A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Functionally relevant domains of the prion protein identified in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Pathologic prion protein infects cells by lipid-raft dependent macropinocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

A deleted prion protein that is neurotoxic in vivo is localized normally in cultured cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

PrP(106-126) does not interact with membranes under physiological conditions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

The cellular prion protein (PrP(C)): its physiological function and role in disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Lethal recessive myelin toxicity of prion protein lacking its central domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Clearance and prevention of prion infection in cell culture by anti-PrP antibodies.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

New insights into prion structure and toxicity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

5 July 2018

Prion disease genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Q/R site editing controls kainate receptor inhibition by membrane fatty acids.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

TRPV1 regulators mediate gentamicin penetration of cultured kidney cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

HEK293 cell line: a vehicle for the expression of recombinant proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Hippocampal synaptic plasticity in mice devoid of cellular prion protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Lentiviral vectors for the delivery of DNA into mammalian cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Neuroprotective functions of prion protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Toxicological and cytophysiological aspects of lanthanides action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Prion diseases: what is the neurotoxic molecule?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic Reticulum.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Gain of function mutants: ion channels and G protein-coupled receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Properties of cytotoxic peptide-formed ion channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Prion protein NMR structure and familial human spongiform encephalopathies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

A transmembrane form of the prion protein in neurodegenerative disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Channel formation by a neurotoxic prion protein fragment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Endogenous chloride channels of insect sf9 cells. Evidence for coordinated activity of small elementary channel units.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Molecular location of a species-specific epitope on the hamster scrapie agent protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924115

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Gap junctions and connexon hemichannels in human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Identification of the heparan sulfate binding sites in the cellular prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano-electrical transducer channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

A novel pathway determining multidrug sensitivity in Schizosaccharomyces pombe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Neurotoxicity of a prion protein fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Prion peptide fragment PrP[106-126] forms distinct cation channel types.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

The toxicity of prion protein fragment PrP(106-126) is not mediated by membrane permeabilization as shown by a M112W substitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

The effect of disease-associated mutations on the folding pathway of human prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Normal host prion protein necessary for scrapie-induced neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Vesicle permeabilization by purified soluble oligomers of prion protein: a comparative study of the interaction of oligomers and monomers with lipid membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Prion protein is necessary for normal synaptic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Prion protein affects Ca2+-activated K+ currents in cerebellar purkinje cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Loss of the cellular prion protein affects the Ca2+ homeostasis in hippocampal CA1 neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.134619

Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20573963

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.134619

1 reference

30 July 2017

1 reference

30 July 2017

1 reference