(Q34074630)

30 July 2017

title

Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation (English)

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30 July 2017

Meritxell Rovira

1

1 reference

30 July 2017

Wei Huang

2

1 reference

30 July 2017

Shamila Yusuff

3

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30 July 2017

Joong Sup Shim

4

1 reference

30 July 2017

Anthony A Ferrante

5

1 reference

30 July 2017

Jun O Liu

6

1 reference

30 July 2017

Michael J Parsons

7

1 reference

30 July 2017

language of work or name

English

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publication date

14 November 2011

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

volume

108

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30 July 2017

issue

48

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30 July 2017

page(s)

19264-19269

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Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing β-cells.

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

c-Kit and stem cell factor regulate PANC-1 cell differentiation into insulin- and glucagon-producing cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre mediated labeling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

IMP dehydrogenase: structure, mechanism, and inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Cyp26 enzymes function in endoderm to regulate pancreatic field size.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Neocuproine ablates melanocytes in adult zebrafish

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Function and regulation of zebrafish nkx2.2a during development of pancreatic islet and ducts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

A clinical drug library screen identifies astemizole as an antimalarial agent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Inosine monophosphate dehydrogenase: A molecular switch integrating pleiotropic GTP-dependent beta-cell functions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Tight links between adenine and guanine nucleotide pools in mouse pancreatic islets: a study with mycophenolic acid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Inhibition of mouse cytosolic aldehyde dehydrogenase by 4-(diethylamino)benzaldehyde

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Asymmetrical retinoic acid synthesis in the dorsoventral axis of the retina

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Establishment of a continuous tumor-cell line (PANC-1) from a human carcinoma of the exocrine pancreas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Disulfiram induces apoptosis in human melanoma cells: a redox-related process.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

In vivo inhibition of aldehyde dehydrogenase by disulfiram

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228434

Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay

28 October 2018

1 reference

12 December 2020

Selective inhibitors of GTP synthesis impede exocytotic insulin release from intact rat islets

1 reference

12 December 2020

Mycophenolic acid is a potent inhibitor of angiogenesis

1 reference

12 December 2020

The new age of chemical screening in zebrafish

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1113081108

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30 July 2017

0 references

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30 July 2017

1 reference