(Q34075980)

English

Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

endoplasmic reticulum

0 references

author name string

Jürgen Gent

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Peter van Kerkhof

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Marcel Roza

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Guojun Bu

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Ger J Strous

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

0 references

publication date

8 July 2002

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

99

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

9858-9863

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

The ubiquitin-proteasome pathway regulates the availability of the GH receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

LRP: a multifunctional scavenger and signaling receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Proteasome inhibitors block a late step in lysosomal transport of selected membrane but not soluble proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Signaling pathways activated by the growth hormone receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

The ubiquitin-proteasome system and endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Transforming growth factor-beta induces formation of a dithiothreitol-resistant type I/Type II receptor complex in live cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. A specific conformational change may be required for full-length receptor signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Linkage of the ubiquitin-conjugating system and the endocytic pathway in ligand-induced internalization of the growth hormone receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Conformational changes required in the human growth hormone receptor for growth hormone signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

A short isoform of the human growth hormone receptor functions as a dominant negative inhibitor of the full-length receptor and generates large amounts of binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Molecular mechanism of growth hormone action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Novel assays based on human growth hormone receptor as alternatives to the rat weight gain bioassay for recombinant human growth hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Receptor-mediated endocytosis of tissue-type plasminogen activator by low density lipoprotein receptor-related protein on human hepatoma HepG2 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Interaction of a 39 kDa protein with the low-density-lipoprotein-receptor-related protein (LRP) on rat hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

The Mouse Fibroblast Growth Hormone Receptor: Ligand Processing and Receptor Modulation and Turnover*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

A specific growth hormone-binding protein in human plasma: initial characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

A Chinese hamster cell cycle mutant arrested at G2 phase has a temperature-sensitive ubiquitin-activating enzyme, E1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Structural design and molecular evolution of a cytokine receptor superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Rational design of potent antagonists to the human growth hormone receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Role of transmembrane domain interactions in the assembly of class II MHC molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

Intracellular Aspects of the Process of Protein Synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

5 July 2018

The single transmembrane domains of ErbB receptors self-associate in cell membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

28 October 2018

The ubiquitin-dependent endocytosis motif is required for efficient incorporation of growth hormone receptor in clathrin-coated pits, but not clathrin-coated lattices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

28 October 2018

Di-leucine-mediated internalization of ligand by a truncated growth hormone receptor is independent of the ubiquitin conjugation system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125043

28 October 2018

Growth hormone (GH) and a GH antagonist promote GH receptor dimerization and internalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12105275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-associated protein is a folding chaperone for low density lipoprotein receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12105275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of receptor dimerization domain residues in growth hormone signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/12105275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythropoietin receptor activation by a ligand-induced conformation change

1 reference

https://pubmed.ncbi.nlm.nih.gov/12105275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocytosis and degradation of the growth hormone receptor are proteasome-dependent

1 reference

https://pubmed.ncbi.nlm.nih.gov/12105275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The YXXL motif, but not the two NPXY motifs, serves as the dominant endocytosis signal for low density lipoprotein receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12105275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12105275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding and functional studies with the growth hormone receptor antagonist, B2036-PEG (pegvisomant), reveal effects of pegylation and evidence that it binds to a receptor dimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12105275

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.152294299

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2002PNAS...99.9858G

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

0 references

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