(Q34084061)

30 July 2017

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title

Molecular pathogenesis of acromegaly (English)

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30 July 2017

Drange MR

1

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30 July 2017

Melmed S

series ordinal

2

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30 July 2017

publication date

1 June 1999

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30 July 2017

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30 July 2017

volume

2

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30 July 2017

issue

1

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30 July 2017

page(s)

43-50

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https://scigraph.springernature.com/pub.10.1023/a:1009917920589

30 July 2017

exact match

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cites work

Endocrine, biochemical, and morphological studies of a pituitary adenoma secreting growth hormone, thyrotropin (TSH), and alpha-subunit: evidence for secretion of TSH with increased bioactivity

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12 December 2020

Loss of heterozygosity studies at the retinoblastoma and breast cancer susceptibility (BRCA2) loci in pituitary, parathyroid, pancreatic and carcinoid tumours.

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12 December 2020

Frequent loss of the P16INK4a gene product in human pituitary tumors

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12 December 2020

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12 December 2020

Familial acromegaly: a specific clinical entity—Further evidence from the genetic study of a three-generation family

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12 December 2020

Dominant inheritance of the complex of myxomas, spotty pigmentation, and endocrine overactivity

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12 December 2020

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

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12 December 2020

Abundance and state of phosphorylation of the retinoblastoma gene product in human pituitary tumors

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12 December 2020

Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)

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12 December 2020

Genetic basis of endocrine disease: pituitary tumor pathogenesis

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12 December 2020

Absence of germ-line mutations of the multiple endocrine neoplasia type 1 (MEN1) gene in familial pituitary adenoma in contrast to MEN1 in Japanese

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12 December 2020

Genomic organization and mutation analysis of p73 in oligodendrogliomas with chromosome 1 p-arm deletions

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12 December 2020

New opportunities for uncovering the molecular basis of cancer

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12 December 2020

p53 expression in pituitary adenomas and carcinomas: correlation with invasiveness and tumor growth fractions.

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12 December 2020

Pituitary pathology in acromegaly.

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12 December 2020

Overexpression of the growth-hormone-releasing hormone gene in acromegaly-associated pituitary tumors. An event associated with neoplastic progression and aggressive behavior.

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12 December 2020

Role of the retinoblastoma gene in the initiation and progression of human cancer

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12 December 2020

Frequent inactivation of the p16 gene in human pituitary tumors by gene methylation

1 reference

12 December 2020

Pituitary Mammosomatotroph Adenomas Develop in Old Mice Transgenic for Growth Hormone-Releasing Hormone

1 reference

12 December 2020

Mutation and expression analysis of the p27/kip1 gene in corticotrophin-secreting tumours

1 reference

12 December 2020

Growth hormone (GH) and prolactin (PRL) gene expression and immunoreactivity in GH- and PRL-producing human pituitary adenomas

1 reference

12 December 2020

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

12 December 2020

Clonal origin of pituitary adenomas

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12 December 2020

Molecular characterization of the men1 tumor suppressor gene in sporadic pituitary tumors

1 reference

12 December 2020

Human growth hormone and prolactin secreting pituitary adenomas analyzed by in situ hybridization

1 reference

12 December 2020

Localisation of a gene causing endocrine neoplasia to a 4 cM region on chromosome 1p35-p36.

1 reference

12 December 2020

Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2.

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12 December 2020

Growth hormone-releasing hormone transcripts in human pituitary adenomas.

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12 December 2020

p53 gene mutations in pituitary adenomas: rare events

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12 December 2020

Chromosome 9p deletions in invasive and noninvasive nonfunctional pituitary adenomas: the deleted region involves markers outside of the MTS1 and MTS2 genes

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12 December 2020

Aberrant p27kip1 expression in endocrine and other tumors

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12 December 2020

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

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12 December 2020

Pituitary carcinoma: a clinicopathologic study of 15 cases

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12 December 2020

Recurrent plurihormonal bimorphous pituitary adenoma producing growth hormone, thyrotropin, and prolactin

1 reference

12 December 2020

Positional cloning of the gene for multiple endocrine neoplasia-type 1

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12 December 2020

The retinoblastoma gene in human pituitary tumors

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12 December 2020

Clinically nonfunctioning pituitary tumors are monoclonal in origin

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12 December 2020

Human pituitary adenomas show no loss of heterozygosity at the retinoblastoma gene locus.

1 reference

12 December 2020

Role of surgery in the management of pituitary tumors

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12 December 2020

Activating mutations of the stimulatory G protein in the McCune-Albright syndrome

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12 December 2020

Presence and characterization of the somatostatin precursor in normal human pituitaries and in growth hormone secreting adenomas

1 reference

12 December 2020

Detection of a potential progenitor cell in the human fetal pituitary that secretes both growth hormone and prolactin

1 reference

12 December 2020

Clinical and biochemical characteristics of acromegalic patients harboring gsp-positive and gsp-negative pituitary tumors

1 reference

12 December 2020

Fine-scale mapping of the gene responsible for multiple endocrine neoplasia type 1 (MEN 1)

1 reference

12 December 2020

Mutations of the MEN1 tumor suppressor gene in pituitary tumors

1 reference

12 December 2020

Loss of heterozygosity at the retinoblastoma locus in human pituitary tumors

1 reference

12 December 2020

Infrequent mutations of p16INK4A and p15INK4B genes in human pituitary adenomas

1 reference

12 December 2020

Acidophil stem cell adenoma of the human pituitary: Clinicopathologic analysis of 15 cases

1 reference

12 December 2020

Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas

1 reference

12 December 2020

Analysis of loss of heterozygosity on chromosome 11 and infrequent inactivation of the MEN1 gene in sporadic pituitary adenomas

1 reference

12 December 2020

Pituitary cells producing more than one hormone human pituitary adenomas

1 reference

12 December 2020

ras mutations in human prolactinomas and pituitary carcinomas

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12 December 2020

Characteristics of gsp-positive growth hormone-secreting pituitary tumors in Korean acromegalic patients

1 reference

12 December 2020

Molecular screening of pituitary adenomas for gene mutations and rearrangements

1 reference

12 December 2020

Frequent loss of heterozygosity at the retinoblastoma susceptibility gene (RB) locus in aggressive pituitary tumors: evidence for a chromosome 13 tumor suppressor gene other than RB.

1 reference

12 December 2020

Expression of growth hormone (GH)-releasing factor gene in GH-producing pituitary adenoma

1 reference

12 December 2020

Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant

1 reference

12 December 2020

Clonal origins of adrenocorticotropin-secreting pituitary tissue in Cushing's disease

1 reference

12 December 2020

Two G protein oncogenes in human endocrine tumors

1 reference

12 December 2020

Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma

1 reference

12 December 2020

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

12 December 2020

Mammosomatotropes: presence and functions in normal and neoplastic pituitary tissue

1 reference

12 December 2020

Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase

1 reference

12 December 2020

G-Protein Oncogenes in Acromegaly

1 reference

12 December 2020

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

1 reference

12 December 2020

The cyclic adenosine 3',5'-monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas

1 reference

12 December 2020

Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism

1 reference

12 December 2020

Effects of an Rb mutation in the mouse

1 reference

12 December 2020

Inactivation of the tumor suppressor gene on 11q13 in brothers with familial acrogigantism without multiple endocrine neoplasia type 1

1 reference

12 December 2020

Human Fetal Adenohypophysis

1 reference

12 December 2020

Menin, the product of the MEN1 gene, is a nuclear protein

1 reference

12 December 2020

Cytogenetic and microsatellite alterations in tumors from patients with the syndrome of myxomas, spotty skin pigmentation, and endocrine overactivity (Carney complex)

1 reference

12 December 2020

Colocalization of growth hormone (GH) and glycoprotein subunit ? in GH-producing pituitary adenomas in acromegalic patients

1 reference

12 December 2020

H-ras mutations in human pituitary carcinoma metastases

1 reference

12 December 2020

Constitutively active Gs alpha is associated with an increased phosphodiesterase activity in human growth hormone-secreting adenomas

1 reference

12 December 2020

Pronostic and therapeutic consequences of Gs alpha mutations in somatotroph adenomas

1 reference

12 December 2020

Infrequent mutations of p27Kip1 gene and trisomy 12 in a subset of human pituitary adenomas

1 reference

12 December 2020

McCune-Albright syndrome and acromegaly: clinical studies and responses to treatment in five cases

1 reference

12 December 2020

Identification of alternatively spliced messenger ribonucleic acid encoding truncated growth hormone-releasing hormone receptor in human pituitary adenomas

1 reference

12 December 2020

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

12 December 2020

Analysis of the Gs alpha gene in growth hormone-secreting pituitary adenomas by the polymerase chain reaction-direct sequencing method using paraffin-embedded tissues

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1009917920589

1 reference

Dimensions Publication ID

30 July 2017

1020326006

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1 reference