(Q34084250)

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Conceptual changes in cancer chemotherapy: from an oral fluoropyrimidine prodrug, UFT, to a novel oral fluoropyrimidine prodrug, S-1, and low-dose FP therapy in Japan

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

Europe PubMed Central

Conceptual changes in cancer chemotherapy: from an oral fluoropyrimidine prodrug, UFT, to a novel oral fluoropyrimidine prodrug, S-1, and low-dose FP therapy in Japan (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Shirasaka T

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Yamamitsu S

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Tsuji A

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Taguchi T

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

1 November 2000

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Investigational New Drugs

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

315-329

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

https://scigraph.springernature.com/pub.10.1023/a:1006476730671

0 references

Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-dose cisplatin and 5-fluorouracil in combination can repress increased gene expression of cellular resistance determinants to themselves

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoimmunosensitization of the T24 human bladder cancer line to Fas-mediated cytotoxicity and apoptosis by cisplatin and 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of uracil and its derivatives on antitumor activity of 5-fluorouracil and 1-(2-tetrahydrofuryl)-5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous infusion of 5-fluorouracil and low dose cisplatin infusion for the treatment of advanced and recurrent gastric adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of uracil and tegafur plus oral leucovorin: an effective oral regimen in the treatment of metastatic colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of inhibition by oxipurinol of 5-FU toxicity against human tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of proliferation of cancer cells in neoplastic effusions in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective antagonism of 5-fluorouracil cytotoxicity by 4-hydroxypyrazolopyrimidine (allopurinol) in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feasibility study on protracted infusional 5-fluorouracil and consecutive low-dose cisplatin for advanced gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the plasma concentration of 5-fluorouracil and the duration of continuous venous infusion of 5-fluorouracil with an inhibitor of 5-fluorouracil degradation on Yoshida sarcomas in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Combination therapy of continuous venous infusion (CVI) of 5-FU and low dose consecutive cisplatin (CDDP), and the new oral anti-cancer drug S-1 for advanced gastro-intestinal cancer]

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitization of human bladder cancer cells to Fas-mediated cytotoxicity by cis-diamminedichloroplatinum (II).

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An early phase II study of oral S-1, a newly developed 5-fluorouracil derivative for advanced and recurrent gastrointestinal cancers. The S-1 Gastrointestinal Cancer Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EXPERIMENTAL EVALUATION OF POTENTIAL ANTICANCER AGENTS. XIII. ON THE CRITERIA AND KINETICS ASSOCIATED WITH "CURABILITY" OF EXPERIMENTAL LEUKEMIA

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of induction of gastrointestinal toxicity in the mouse by 5-fluorouracil, 5-fluorouridine, and 5-fluoro-2'-deoxyuridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of S-1, a novel oral derivative of 5-fluorouracil, in advanced gastric cancer. For the S-1 Cooperative Gastric Cancer Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

INVESTIGATIONS WITH 5-AZAOROTIC ACID, AN INHIBITOR OF THE BIOSYNTHESIS OF PYRIMIDINES DE NOVO

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in folate concentration in Yoshida sarcoma after administration of leucovorin or cisplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Fluorouracil incorporation into DNA of CF-1 mouse bone marrow cells as a possible mechanism of toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic basis of the synergistic antitumor activities of 5-fluorouracil and cisplatin in rodent tumor models in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled trial of the effect of 4-hydroxypyrazolopyrimidine (allopurinol) on the toxicity of a single bolus dose of 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical modulation of 5-FU--effect of low dose CDDP

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopurinol modification of the toxicity and antitumor activity of 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic study of S-1, a novel oral fluorouracil antitumor drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analogs of pyrimidine nucleosides. I. N1-(alpha-furanidyl) derivatives of natural pyrimidine bases and their antimetabolities

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CELL PROLIFERATION KINETICS IN THE GASTROINTESTINAL TRACT OF MAN. II. CELL RENEWAL IN STOMACH, ILEUM, COLON, AND RECTUM

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Ambulatory and domiciliary cancer chemotherapy with forearm implant catheter system and low-dose CDDP + 5-FU therapy].

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative studies on the metabolism of 2-(tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of amino acid transport by cis-diamminedichloroplatinum(II) derivatives in L1210 murine leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-FU and allopurinol: toxicity modulation and phase II results in colon cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11081568

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1006476730671

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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