(Q34084985)

30 July 2017

title

An innovative approach for the characterization of the isoforms of a monoclonal antibody product (English)

1 reference

30 July 2017

1 reference

1 reference

Shanmuuga Sundaram

1

1 reference

30 July 2017

Alice Matathia

2

1 reference

30 July 2017

Jun Qian

3

1 reference

30 July 2017

Jingming Zhang

4

1 reference

30 July 2017

Ming-Ching Hsieh

5

1 reference

30 July 2017

Tun Liu

6

1 reference

30 July 2017

Richard Crowley

7

1 reference

30 July 2017

Babita Parekh

8

1 reference

30 July 2017

Qinwei Zhou

9

1 reference

30 July 2017

publication date

1 November 2011

1 reference

30 July 2017

published in

Monoclonal Antibodies

1 reference

30 July 2017

volume

3

1 reference

30 July 2017

issue

6

1 reference

30 July 2017

page(s)

505-512

1 reference

New drugs in melanoma: it's a whole new world

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Antibody-based therapeutics to watch in 2011.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Metrics for antibody therapeutics development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Engineering host cell lines to reduce terminal sialylation of secreted antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Current and emerging treatment strategies for cutaneous T-cell lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Improving effector functions of antibodies for cancer treatment: Enhancing ADCC and CDC

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Antibodies for the treatment of bacterial infections: current experience and future prospects

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Recombinant antibodies as therapeutic agents: pathways for modeling new biodrugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

N-glycans of recombinant human interferon-gamma change during batch culture of chinese hamster ovary cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Beta-elimination and peptide bond hydrolysis: two distinct mechanisms of human IgG1 hinge fragmentation upon storage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Structural characterization of N-linked oligosaccharides on monoclonal antibody cetuximab by the combination of orthogonal matrix-assisted laser desorption/ionization hybrid quadrupole-quadrupole time-of-flight tandem mass spectrometry and sequentia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Development and regulation of monoclonal antibody products: challenges and opportunities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Therapeutic antibodies for human diseases at the dawn of the twenty-first century

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Degradative covalent reactions important to protein stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Glycosylation of antibody molecules: structural and functional significance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Processing of C-terminal lysine and arginine residues of proteins isolated from mammalian cell culture.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Tertiary Structure Is a Principal Determinant to Protein Deamidation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Succinimide formation from aspartyl and asparaginyl peptides as a model for the spontaneous degradation of proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Stability of protein pharmaceuticals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

A comparative study of the N-linked oligosaccharide structures of human IgG subclass proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Effects of amino acid sequence, buffers, and ionic strength on the rate and mechanism of deamidation of asparagine residues in small peptides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Different culture methods lead to differences in glycosylation of a murine IgG monoclonal antibody

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Characterization of antibody charge heterogeneity resolved by preparative immobilized pH gradients

5 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.18090

Analysis of isoaspartate in a recombinant monoclonal antibody and its charge isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.18090

Evidence for trisulfide bonds in a recombinant variant of a human IgG2 monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.18090

Microheterogeneity of erythropoietin carbohydrate structure

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.18090

Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.18090

Influence of Primatone RL supplementation on sialylation of recombinant human interferon-gamma produced by Chinese hamster ovary cell culture using serum-free media

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Comparison of the isoelectric focusing patterns of darbepoetin alfa, recombinant human erythropoietin, and endogenous erythropoietin from human urine.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242836

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

28 October 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.3.6.18090

Characterization of a novel modification to monoclonal antibodies: thioether cross-link of heavy and light chains

21 January 2018

1 reference

12 December 2020

Determination of the origin of charge heterogeneity in a murine monoclonal antibody

1 reference

12 December 2020

Real-time isoform analysis by two-dimensional chromatography of a monoclonal antibody during bioreactor fermentations

1 reference

12 December 2020

Identification of sites of degradation in a therapeutic monoclonal antibody by peptide mapping

1 reference

12 December 2020

Points to consider in the manufacture and testing of monoclonal antibody products for human use (1997). U.S. Food and Drug Administration Center for Biologics Evaluation and Research

1 reference

12 December 2020

Identifiers

DOI

10.4161/MABS.3.6.18090

1 reference

30 July 2017

1 reference

30 July 2017

1 reference