(Q34086847)

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Receptor activator of nuclear factor-kappaB ligand and osteoprotegerin: potential implications for the pathogenesis and treatment of malignant bone diseases

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Europe PubMed Central

PubMed publication ID

30 July 2017

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Europe PubMed Central

Receptor activator of nuclear factor-kappaB ligand and osteoprotegerin: potential implications for the pathogenesis and treatment of malignant bone diseases (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Hofbauer LC

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Neubauer A

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Heufelder AE

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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publication date

1 August 2001

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

92

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

460-470

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Pathophysiologic interactions in skeletal metastasis

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Molecular mechanisms of osteolytic bone metastases

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21 January 2018

Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families

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21 January 2018

The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

1 reference

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21 January 2018

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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21 January 2018

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

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21 January 2018

TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

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21 January 2018

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

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21 January 2018

Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival

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21 January 2018

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

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21 January 2018

Cancer cells responsible for humoral hypercalcemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation

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21 January 2018

Localization of RANKL (receptor activator of NF kappa B ligand) mRNA and protein in skeletal and extraskeletal tissues.

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21 January 2018

Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures.

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21 January 2018

TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts.

1 reference

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21 January 2018

The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.

1 reference

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21 January 2018

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1 reference

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21 January 2018

TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor

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21 January 2018

TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activation

1 reference

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21 January 2018

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

1 reference

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21 January 2018

Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis

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21 January 2018

Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells

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21 January 2018

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

1 reference

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21 January 2018

Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines

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21 January 2018

Structure of the mouse osteoclastogenesis inhibitory factor (OCIF) gene and its expression in embryogenesis

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Establishment and characterization of an immortal macrophage-like cell line inducible to differentiate to osteoclasts.

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21 January 2018

Osteoclastogenesis inhibitory factor (OCIF) directly inhibits bone-resorbing activity of isolated mature osteoclasts.

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21 January 2018

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

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Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin

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21 January 2018

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

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21 January 2018

RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis

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21 January 2018

Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif

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21 January 2018

The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor

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21 January 2018

TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src

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RANKing the importance of measles virus in Paget's disease

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21 January 2018

Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors

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Sequential requirements for SCL/tal-1, GATA-2, macrophage colony-stimulating factor, and osteoclast differentiation factor/osteoprotegerin ligand in osteoclast development

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21 January 2018

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

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RANK is essential for osteoclast and lymph node development

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TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.

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Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation

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Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression

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The effect of a single dose of osteoprotegerin in postmenopausal women

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Glucocorticoid decreases circulating osteoprotegerin (OPG): possible mechanism for glucocorticoid induced osteoporosis

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1,25-Dihydroxyvitamin D3 hypersensitivity of osteoclast precursors from patients with Paget's disease

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Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone

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Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis

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Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formation

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Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of bone

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Parathyroid hormone-related protein in hypercalcemia associated with hematological malignancy

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STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroi

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A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.

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21 January 2018

Identifiers

10.1002/1097-0142(20010801)92:3<460::AID-CNCR1344>3.0.CO;2-D

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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