(Q34089314)

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A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells.

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10 November 2019

A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells (English)

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10 November 2019

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10 November 2019

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Chernova OB

1

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10 November 2019

Hunyadi A

2

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10 November 2019

Malaj E

3

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10 November 2019

Pan H

4

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10 November 2019

Crooks C

5

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10 November 2019

Roe B

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10 November 2019

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1 August 2001

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10 November 2019

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10 November 2019

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10 November 2019

5378-5392

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10 November 2019

38

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10 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204694

0 references

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Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas.

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Molecular definition of chromosome translocations involving 10q24 and 19q13 in human malignant glioma cells

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A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors

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Base-calling of automated sequencer traces using phred. I. Accuracy assessment

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Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter

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21 January 2018

PTEN / MMAC1 mutation and frequent loss of heterozygosity identified in chromosome 10q in a subset of hepatocellular carcinomas.

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Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme

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Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades.

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21 January 2018

Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10.

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The impact of L1 retrotransposons on the human genome

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Primate origin of the CMT1A-REP repeat and analysis of a putative transposon-associated recombinational hotspot

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours

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A tiger behind many doors: multiple genetic pathways to malignant glioma

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New deletion in low-grade oligodendroglioma at the glioblastoma suppressor locus on chromosome 10q25-26.

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21 January 2018

Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas.

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Loss of heterozygosity on chromosome 19 in secondary glioblastomas.

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The ancient regulatory-protein family of WD-repeat proteins

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G protein heterodimers: new structures propel new questions

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Genetic alterations associated with the evolution and progression of astrocytic brain tumours

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Recombination hot spots and human disease

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Chromosomal translocations in human cancer.

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A recombination hotspot responsible for two inherited peripheral neuropathies is located near a mariner transposon-like element.

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NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma

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Molecular evolution of the second ancient human mariner transposon, Hsmar2, illustrates patterns of neutral evolution in the human genome lineage

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Comparative molecular genetic profiles of anaplastic astrocytomas/glioblastomas multiforme and their subsequent recurrences.

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21 January 2018

Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype.

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The WD repeat: a common architecture for diverse functions

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Molecular analysis of two putative tumour suppressor genes, PTEN and DMBT, which have been implicated in glioblastoma multiforme disease progression.

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Deletion mapping of chromosome 10 in human glioma.

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

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PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas.

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The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

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Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors

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Advances in the molecular genetics of gliomas.

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Non-homologous recombination between Alu and LINE-1 repeats caused a 430-kb deletion in the dystrophin gene: a novel source of genomic instability

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10.1038/SJ.ONC.1204694

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10 November 2019

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10 November 2019

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