(Q34091001)

30 July 2017

title

Modifying histones to tame cancer: clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors (English)

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30 July 2017

Gore SD

1

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30 July 2017

Carducci MA

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 December 2000

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Expert Opinion on Investigational Drugs

30 July 2017

published in

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30 July 2017

volume

9

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30 July 2017

issue

12

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30 July 2017

page(s)

2923-2934

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Role of chromatin structure in the regulation of transcription by RNA polymerase II.

30 July 2017

cites work

1 reference

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Covalent modifications of histones: expression from chromatin templates

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Histone acetylation and transcriptional regulatory mechanisms

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Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function

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Retinoblastoma protein recruits histone deacetylase to repress transcription

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

21 January 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

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Sodium butyrate inhibits histone deacetylation in cultured cells

21 January 2018

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Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences

21 January 2018

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Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate

21 January 2018

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Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs.

21 January 2018

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Treatment of episodic hyperammonemia in children with inborn errors of urea synthesis

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Prospective treatment of urea cycle disorders.

21 January 2018

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Syndrome of idiopathic hyperammonemia after high-dose chemotherapy: review of nine cases

21 January 2018

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Phenylacetylglutamine May Replace Urea as a Vehicle for Waste Nitrogen Excretion

21 January 2018

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Stopping the biologic clock for globin gene switching

21 January 2018

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Disposition of phenylbutyrate and its metabolites, phenylacetate and phenylacetylglutamine.

21 January 2018

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A histone deacetylase inhibitor potentiates retinoid receptor action in embryonal carcinoma cells

21 January 2018

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 January 2018

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FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

21 January 2018

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Effects of a novel antitumor depsipeptide, FR901228, on human breast cancer cells.

21 January 2018

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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

21 January 2018

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Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

21 January 2018

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10.1517/13543784.9.12.2923

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference