(Q34091124)

30 July 2017

title

CCR2 plays a critical role in dendritic cell maturation: possible role of CCL2 and NF-kappa B. (English)

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30 July 2017

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Fabio Jimenez

1

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30 July 2017

Marlon P Quinones

2

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30 July 2017

Hernan G Martinez

3

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30 July 2017

Carlos A Estrada

4

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30 July 2017

Kassandra Clark

5

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30 July 2017

Edgar Garavito

6

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30 July 2017

Jessica Ibarra

7

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30 July 2017

Peter C Melby

8

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30 July 2017

Seema S Ahuja

9

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30 July 2017

language of work or name

English

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publication date

19 April 2010

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30 July 2017

published in

Journal of Immunology

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30 July 2017

volume

184

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30 July 2017

issue

10

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30 July 2017

page(s)

5571-5581

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Feed-forward signaling of TNF-alpha and NF-kappaB via IKK-beta pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice

30 July 2017

cites work

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5 July 2018

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Distinct roles of different NF-kappa B subunits in regulating inflammatory and T cell stimulatory gene expression in dendritic cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Discovery and pharmacological characterization of a novel rodent-active CCR2 antagonist, INCB3344.

5 July 2018

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Maturation of function in dendritic cells for tolerance and immunity.

5 July 2018

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Dendritic-cell trafficking to lymph nodes through lymphatic vessels

5 July 2018

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Conditions influencing the efficacy of vaccination with live organisms against Leishmania major infection

5 July 2018

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CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells

5 July 2018

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Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

5 July 2018

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Factors and signals that govern the migration of dendritic cells via lymphatics: recent advances

5 July 2018

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The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis

5 July 2018

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Chemokine mediated control of dendritic cell migration and function.

5 July 2018

1 reference

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Langerhans cells renew in the skin throughout life under steady-state conditions

5 July 2018

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Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Chemokines and dendritic cell traffic.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 c

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Chemokines and cell migration in secondary lymphoid organs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Dendritic cell (DC)-based anti-infective strategies: DCs engineered to secrete IL-12 are a potent vaccine in a murine model of an intracellular infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Distinct dendritic cell subsets differentially regulate the class of immune response in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Dendritic cells and the control of immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Recombinant interleukin 12 cures mice infected with Leishmania major

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Migration and maturation of Langerhans cells in skin transplants and explants

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Dendritic cell differentiation state and their interaction with NKT cells determine Th1/Th2 differentiation in the murine model of Leishmania major infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Protection of susceptible BALB/c mice from challenge with Leishmania major by nucleoside hydrolase, a soluble exo-antigen of Leishmania.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Two waves of antigen-containing dendritic cells in vivo in experimental Leishmania major infection

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

RNA interference shows critical requirement for NF-kappa B p50 in the production of IL-12 by human dendritic cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kappaB-dependent maturation of normal and leukemic myeloid cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Enhanced contact hypersensitivity in human monocyte chemoattractant protein-1 transgenic mouse

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Possible new role for NF-kappaB in the resolution of inflammation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Role of NFkappaB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Preformed membrane-associated stores of interleukin (IL)-12 are a previously unrecognized source of bioactive IL-12 that is mobilized within minutes of contact with an intracellular parasite

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Monocyte chemoattractant protein-1 mediates cockroach allergen-induced bronchial hyperreactivity in normal but not CCR2-/- mice: the role of mast cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Murine dendritic cells internalize Leishmania major promastigotes, produce IL-12 p40 and stimulate primary T cell proliferation in vitro.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Dendritic cell survival and maturation are regulated by different signaling pathways.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

CCR5 provides a signal for microbial induced production of IL-12 by CD8α+ dendritic cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929965

Inhibition of NF-kappaB activation by pyrrolidine dithiocarbamate prevents In vivo expression of proinflammatory genes

28 October 2018

1 reference

12 December 2020

FLT3 ligand induces the generation of functionally active dendritic cells in mice

1 reference

12 December 2020

Pyrrolidine dithiocarbamate attenuates endotoxin-induced acute lung injury

1 reference

12 December 2020

Differential responsiveness to constitutive vs. inducible chemokines of immature and mature mouse dendritic cells

1 reference

12 December 2020

Balance between NF- B and JNK/AP-1 activity controls dendritic cell life and death

1 reference

12 December 2020

Antigen-specific peripheral tolerance induced by topical application of NF-kappaB decoy oligodeoxynucleotide

1 reference

12 December 2020

Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection

1 reference

12 December 2020

Differential regulation of epidermal and dermal dendritic cells by IL-12 and Flt3 ligand

1 reference

12 December 2020

Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis

1 reference

12 December 2020

Dendritic cell development and survival require distinct NF-kappaB subunits

1 reference

12 December 2020

Differential roles of CC chemokine ligand 2/monocyte chemotactic protein-1 and CCR2 in the development of T1 immunity

1 reference

12 December 2020

CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB

1 reference

12 December 2020

Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens

1 reference

12 December 2020

CC chemokine receptor 2 expression in donor cells serves an essential role in graft-versus-host-disease

1 reference

12 December 2020

TNF-alpha, RANTES, and MCP-1 are major chemoattractants of murine Langerhans cells to the regional lymph nodes

1 reference

12 December 2020

CC chemokine receptors, CCR-1 and CCR-3, are potentially involved in antigen-presenting cell function of human peripheral blood monocyte-derived dendritic cells

1 reference

12 December 2020

An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha

1 reference

12 December 2020

CCL2-independent role of CCR2 in immune responses against Leishmania major

1 reference

12 December 2020

Critical role of dendritic cells in determining the Th1/Th2 balance upon Leishmania major infection

1 reference

12 December 2020

Langerin Expressing Cells Promote Skin Immune Responses under Defined Conditions

1 reference

12 December 2020

Phenotypic and functional differences between wild-type and CCR2-/- dendritic cells: implications for islet transplantation

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0803494

1 reference

30 July 2017

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30 July 2017

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