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Expression of reticulon 3 in Alzheimer's disease brain.
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1 reference
stated in
Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
title
Expression of reticulon 3 in Alzheimer's disease brain
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
main subject
Alzheimer's disease
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author
Fuyuki Kametani
series ordinal
4
1 reference
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Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Wataru Araki
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5
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Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
author name string
H Kume
series ordinal
1
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2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Y Konishi
series ordinal
2
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PMC publication ID
2930375
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
K S Murayama
series ordinal
3
1 reference
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Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
publication date
1 April 2009
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Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
published in
Neuropathology and Applied Neurobiology
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Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
volume
35
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2930375
reference URL
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retrieved
23 January 2020
issue
2
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Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
page(s)
178-188
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Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
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The reticulons: a family of proteins with diverse functions
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PubMed Central
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5 July 2018
Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities
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Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo
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Brain site-specific gene expression analysis in Alzheimer's disease patients
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Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein.
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BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.
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Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model
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Tissue specificity and regulation of the N-terminal diversity of reticulon 3
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In vivo inhibition of Abeta production by memapsin 2 (beta-secretase) inhibitors
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Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease
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BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics
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Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation
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The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the down critical region
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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase
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5 July 2018
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Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks beta/A4 amyloid immunoreactivity.
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Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis.
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Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice
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28 October 2018
Neuronal and nonneuronal quantitative BACE immunocytochemical expression in the entorhinohippocampal and frontal regions in Alzheimer's disease.
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28 October 2018
Transgenic BACE expression in mouse neurons accelerates amyloid plaque pathology
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28 October 2018
Reticulon3 expression in rat optic and olfactory systems.
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28 October 2018
BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease
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28 October 2018
Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease
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28 October 2018
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930375
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28 October 2018
Localization of beta-secretase memapsin 2 in the brain of Alzheimer's patients and normal aged controls
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930375
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28 October 2018
Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
1 reference
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reference URL
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retrieved
28 October 2018
Identifiers
DOI
10.1111/J.1365-2990.2008.00974.X
1 reference
stated in
Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
PMC publication ID
2930375
1 reference
stated in
Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
PubMed ID
19284479
1 reference
stated in
Europe PubMed Central
PMC publication ID
2930375
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19284479%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
ResearchGate publication ID
24199175
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