(Q34094833)

31 July 2017

title

Catalytic inhibition of human DNA topoisomerase IIalpha by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum). (English)

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31 July 2017

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Peebles KA

1

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31 July 2017

Baker RK

2

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31 July 2017

Kurz EU

3

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31 July 2017

Schneider BJ

4

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31 July 2017

Kroll DJ

5

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31 July 2017

language of work or name

English

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publication date

1 October 2001

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31 July 2017

published in

Biochemical Pharmacology

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31 July 2017

volume

62

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31 July 2017

issue

8

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31 July 2017

page(s)

1059-1070

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Comparison of an extract of hypericum (LI 160) and sertraline in the treatment of depression: a double-blind, randomized pilot study

31 July 2017

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7 January 2021

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St John's wort for depression--an overview and meta-analysis of randomised clinical trials

7 January 2021

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Equivalence of St John's wort extract (Ze 117) and fluoxetine: a randomized, controlled study in mild-moderate depression.

7 January 2021

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Attenuation of alcohol intake by extract of Hypericum perforatum (St. John's Wort) in two different strains of alcohol-preferring rats

7 January 2021

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Potential metabolic interaction between St. John's wort and theophylline

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Indinavir concentrations and St John's wort.

7 January 2021

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Acute heart transplant rejection due to Saint John's wort

7 January 2021

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Inhibition of benzodiazepine binding in vitro by amentoflavone, a constituent of various species of Hypericum.

7 January 2021

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Effects of Hypericum perforatum on levels of 5-hydroxytryptamine, noradrenaline and dopamine in the cortex, diencephalon and brainstem of the rat.

7 January 2021

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Hyperforin as a possible antidepressant component of hypericum extracts

7 January 2021

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In vitro receptor binding and enzyme inhibition by Hypericum perforatum extract

7 January 2021

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Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

7 January 2021

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Hypericin site specific interactions within polynucleotides used as DNA model compounds

7 January 2021

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Subcellular distribution of hypericin in human cancer cells

7 January 2021

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Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated?

7 January 2021

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Secondary leukemias induced by topoisomerase-targeted drugs

7 January 2021

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The ortho-quinone metabolite of the anticancer drug etoposide (VP-16) is a potent inhibitor of the topoisomerase II/DNA cleavable complex

7 January 2021

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Modulation of human DNA topoisomerase IIalpha function by interaction with 14-3-3epsilon

7 January 2021

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Characterization of the interaction between topoisomerase II and DNA by transcriptional footprinting

7 January 2021

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Homologous and heterologous protein-protein interactions of human DNA topoisomerase IIalpha

7 January 2021

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A rapid method for the measurement of the unwinding angle of intercalating agents and the superhelix density of circular DNAs

7 January 2021

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Altered gene expression in human leukemia K562 cells selected for resistance to etoposide

7 January 2021

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The CAT-Tox (L) assay: a sensitive and specific measure of stress-induced transcription in transformed human liver cells

7 January 2021

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Inhibition of epipodophyllotoxin cytotoxicity by interference with topoisomerase-mediated DNA cleavage

7 January 2021

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Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide

7 January 2021

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St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

7 January 2021

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Association of CYP3A4 genotype with treatment-related leukemia

7 January 2021

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Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: free radical/antioxidant approach

7 January 2021

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Regulation of topoisomerase II expression during the VM-26 induced differentiation of IW32 murine erythroleukemia cells

7 January 2021

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Use of complementary/alternative medicine by breast cancer survivors in Ontario: prevalence and perceptions

7 January 2021

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Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology

7 January 2021

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10.1016/S0006-2952(01)00759-6

7 January 2021

Identifiers

DOI

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31 July 2017

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