(Q34099816)

31 July 2017

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title

Pharmacokinetically guided administration of chemotherapeutic agents (English)

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31 July 2017

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van den Bongard HJ

1

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31 July 2017

Mathôt RA

series ordinal

2

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31 July 2017

Beijnen JH

series ordinal

3

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31 July 2017

Schellens JH

series ordinal

4

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31 July 2017

1 November 2000

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Clinical Pharmacokinetics

31 July 2017

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31 July 2017

39

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31 July 2017

345-367

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31 July 2017

5

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https://scigraph.springernature.com/pub.10.2165/00003088-200039050-00004

31 July 2017

0 references

cites work

Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00003088-200039050-00004

Clinical pharmacokinetics of etoposide during 120 hours continuous infusions in solid tumours

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00003088-200039050-00004

Phase I and pharmacological study of sequential intravenous topotecan and oral etoposide

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00003088-200039050-00004

Phase I clinical and pharmacological study of thymidine (NSC 21548) and cis-diamminedichloroplatinum(II) in patients with advanced cancer.

21 January 2018

1 reference

12 December 2020

Limited sampling models for topotecan pharmacokinetics

1 reference

12 December 2020

Phase II study of 4'-iodo-4'-deoxydoxorubicin in non-resectable non-small-cell lung cancer

1 reference

12 December 2020

Ifosfamide, carboplatin, and etoposide plus granulocyte-macrophage colony-stimulating factor: a phase I study with apparent activity in non-small-cell lung cancer

1 reference

12 December 2020

Phase I trial, including pharmacokinetic and pharmacodynamic correlations, of combination paclitaxel and carboplatin in patients with metastatic non-small-cell lung cancer

1 reference

12 December 2020

Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Pharmacokinetics and cancer chemotherapy

1 reference

12 December 2020

Validation of a limited sampling model for carboplatin in a high-dose chemotherapy combination

1 reference

12 December 2020

Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic analysis of fluorouracil during 72-hour continuous infusion with and without dipyridamole

1 reference

12 December 2020

A Bayesian dosing method for carboplatin given by continuous infusion for 120 h.

1 reference

12 December 2020

Effects of cisplatin on different measures of glomerular function in the human kidney with special emphasis on high-dose.

1 reference

12 December 2020

Phase I and pharmacologic study of oral topotecan administered twice daily for 21 days to adult patients with solid tumors

1 reference

12 December 2020

Therapeutic monitoring of continuous infusion etoposide in small-cell lung cancer

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of topotecan administered daily for 5 days every 3 weeks

1 reference

12 December 2020

A limited sampling method for estimation of the carboplatin area under the curve.

1 reference

12 December 2020

Prolonged infusion of hexamethylene bisacetamide: a phase I and pharmacological study

1 reference

12 December 2020

Phase I trial using adaptive control dosing of hexamethylene bisacetamide (NSC 95580).

1 reference

12 December 2020

Pharmacologically based dosing of etoposide: a means of safely increasing dose intensity

1 reference

12 December 2020

Pharmacokinetics of continuous-infusion amsacrine and teniposide for the treatment of relapsed childhood acute nonlymphocytic leukemia.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of 21-day continuous oral etoposide in pediatric patients with solid tumors

1 reference

12 December 2020

The optimisation of carboplatin dose in carboplatin, etoposide and bleomycin combination chemotherapy for good prognosis metastatic nonseminomatous germ cell tumours of the testis

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of locoregional 5 fluorouracil (5FU) in advanced colorectal liver metastases

1 reference

12 December 2020

Limited-sampling models for anticancer agents

1 reference

12 December 2020

DoseVersus pharmacokinetics for predicting tolerance to 5-day continuous infusion of 5-FU

1 reference

12 December 2020

Circadian rhythm of 5-fluorouracil population pharmacokinetics in patients with metastatic colorectal cancer.

1 reference

12 December 2020

Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule

1 reference

12 December 2020

Paclitaxel combined with carboplatin in the first-line treatment of advanced ovarian cancer: a phase I trial

1 reference

12 December 2020

Phase I clinical and pharmacokinetic trial of oral menogaril administered on three consecutive days.

1 reference

12 December 2020

Docetaxel (Taxotere): an active drug for the treatment of patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group.

1 reference

12 December 2020

Cyclophosphamide pharmacokinetics: correlation with cardiac toxicity and tumor response

1 reference

12 December 2020

Patient characteristics associated with high-risk methotrexate concentrations and toxicity

1 reference

12 December 2020

Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer.

1 reference

12 December 2020

A comparison of methods of calculation for estimating carboplatin AUC with a retrospective pharmacokinetic-pharmacodynamic analysis in patients with advanced non-small cell lung cancer. European Lung Cancer Working Party.

1 reference

12 December 2020

Platinum-DNA damage in leukocyte DNA of patients receiving carboplatin and cisplatin chemotherapy, measured by atomic absorption spectrometry

1 reference

12 December 2020

Escalating teniposide systemic exposure to increase dose intensity for pediatric cancer patients.

1 reference

12 December 2020

Phase I clinical and pharmacokinetic study of taxol.

1 reference

12 December 2020

Clinical Pharmacokinetics of Carboplatin

1 reference

12 December 2020

Pharmacology and Clinical Toxicity of 4'-Iodo-4'-deoxydoxorubicin: An Example of Successful Application of Pharmacokinetics to Dose Escalation in Phase I Trials

1 reference

12 December 2020

A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children

1 reference

12 December 2020

High-performance liquid chromatographic assay for taxol in human plasma and urine and pharmacokinetics in a phase I trial

1 reference

12 December 2020

Carboplatin in combination with paclitaxel in advanced ovarian cancer: dose determination and pharmacokinetic and pharmacodynamic interactions

1 reference

12 December 2020

A phase I clinical and pharmacologic study of a carboplatin and irinotecan regimen combined with recombinant human granulocyte-colony stimulating factor in the treatment of patients with advanced nonsmall cell lung carcinoma.

1 reference

12 December 2020

Individual dose adaptation of anticancer drugs.

1 reference

12 December 2020

Relationship between fluorouracil systemic exposure and tumor response and patient survival

1 reference

12 December 2020

Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy

1 reference

12 December 2020

Evaluation of formulas using the serum creatinine level to calculate the optimal dosage of carboplatin.

1 reference

12 December 2020

Saturable pharmacokinetics and paclitaxel pharmacodynamics in children with solid tumors

1 reference

12 December 2020

A comparison of methods for limited-sampling strategy design using data from a phase I trial of the anthrapyrazole DuP-941.

1 reference

12 December 2020

Association of busulfan area under the curve with veno-occlusive disease following BMT.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of long-term continuous-infusion doxorubicin

1 reference

12 December 2020

Validation of techniques for the prediction of carboplatin exposure: application of Bayesian methods.

1 reference

12 December 2020

Pharmacodynamics in cancer therapy

1 reference

12 December 2020

Pharmacokinetic modelling--a prelude to therapeutic drug monitoring for all cancer patients?

1 reference

12 December 2020

Adaptive control of etoposide administration: impact of interpatient pharmacodynamic variability.

1 reference

12 December 2020

A phase II trial with docetaxel (Taxotere) in second line treatment with chemotherapy for advanced breast cancer. A study of the EORTC Early Clinical Trials Group.

1 reference

12 December 2020

Improvement of the Cockcroft-Gault equation for predicting glomerular filtration in cancer patients.

1 reference

12 December 2020

Plasma platinum levels: relationship to cisplatin dose and nephrotoxicity

1 reference

12 December 2020

Impact of cyclophosphamide on relationships between carboplatin exposure and response or toxicity when used in the treatment of advanced ovarian cancer

1 reference

12 December 2020

Phase I trial of granulocyte-macrophage colony-stimulating factor plus high-dose cyclophosphamide given every 2 weeks: a Cancer and Leukemia Group B study

1 reference

12 December 2020

Dose calculation of anticancer drugs: a review of the current practice and introduction of an alternative

1 reference

12 December 2020

Plasma free platinum pharmacokinetics in patients treated with high dose carboplatin

1 reference

12 December 2020

5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer

1 reference

12 December 2020

Phase I clinical and pharmacological study of 72-hour continuous infusion of etoposide in patients with advanced cancer

1 reference

12 December 2020

Estimation of the area under the concentration-versus-time curve of carboplatin following irinotecan using a limited sampling model

1 reference

12 December 2020

Pharmacokinetics and metabolism of 4'-iodo-4'-deoxy-doxorubicin in humans

1 reference

12 December 2020

Optimization of busulfan dosage in children undergoing bone marrow transplantation: a pharmacokinetic study of dose escalation

1 reference

12 December 2020

Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect

1 reference

12 December 2020

Anticancer drug renal toxicity and elimination: dosing guidelines for altered renal function

1 reference

12 December 2020

Clinical pharmacokinetic study of 5-FU in continuous 5-day infusions for head and neck cancer

1 reference

12 December 2020

High failure rate of carboplatin-etoposide combination in good risk non-seminomatous germ cell tumours

1 reference

12 December 2020

Busulfan disposition: the role of therapeutic monitoring in bone marrow transplantation induction regimens

1 reference

12 December 2020

Clinical pharmacodynamics of continuous infusion topotecan in children: systemic exposure predicts hematologic toxicity

1 reference

12 December 2020

Prediction of carboplatin clearance calculated by patient characteristics or 24-hour creatinine clearance: a comparison of the performance of three formulae.

1 reference

12 December 2020

Pharmacokinetically guided dose escalation of carboplatin in epithelial ovarian cancer: effect on drug-plasma AUC and peripheral blood drug-DNA adduct levels

1 reference

12 December 2020

Pharmacokinetics of paclitaxel and carboplatin in combination.

1 reference

12 December 2020

Prospective validation of a pharmacologically based dosing scheme for the cis-diamminedichloroplatinum(II) analogue diamminecyclobutanedicarboxylatoplatinum

1 reference

12 December 2020

Phase I and pharmacological study of vinblastine by prolonged continuous infusion

1 reference

12 December 2020

Revisiting some factors contributing to variability

1 reference

12 December 2020

Phase I study of pharmacologically based dosing of carboplatin with filgrastim support in women with epithelial ovarian cancer

1 reference

12 December 2020

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients

1 reference

12 December 2020

A phase I clinical and pharmacokinetic study of carboplatin and autologous bone marrow support

1 reference

12 December 2020

The use of the Calvert formula to determine the optimal carboplatin dosage

1 reference

12 December 2020

Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans

1 reference

12 December 2020

Phase I clinical and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered as a five-day continuous infusion.

1 reference

12 December 2020

Pharmacokinetics of oral idarubicin in breast cancer patients with reference to antitumor activity and side effects

1 reference

12 December 2020

Effect of human renal and hepatic disease on the pharmacokinetics of anticancer drugs

1 reference

12 December 2020

Dose optimisation of carboplatin in adults.

1 reference

12 December 2020

Adjustment of creatinine clearance improves accuracy of Calvert's formula for carboplatin dosing

1 reference

12 December 2020

High-dose methotrexate: a clinical and pharmacokinetic evaluation. Treatment of advanced squamous cell carcinoma of the head and neck using a prospective mathematical model and pharmacokinetic surveillance.

1 reference

12 December 2020

A review of the pharmacokinetics and pharmacodynamics of combination carboplatin/paclitaxel.

1 reference

12 December 2020

Phase II and pharmacologic study of docetaxel as initial chemotherapy for metastatic breast cancer

1 reference

12 December 2020

Randomized trial of dose-intensity with single-agent carboplatin in patients with epithelial ovarian cancer. London Gynaecological Oncology Group

1 reference

12 December 2020

Prediction of creatinine clearance from serum creatinine

1 reference

12 December 2020

A limited-sampling model for the pharmacokinetics of carboplatin administered in combination with paclitaxel

1 reference

12 December 2020

Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: comparison with in vitro adduct formation

1 reference

12 December 2020

Busulfan disposition and hepatic veno-occlusive disease in children undergoing bone marrow transplantation

1 reference

12 December 2020

Clinical impact of pharmacokinetically-guided dose adaptation of 5-fluorouracil: results from a multicentric randomized trial in patients with locally advanced head and neck carcinomas

1 reference

12 December 2020

Clinical pharmacodynamics of continuous infusion teniposide: systemic exposure as a determinant of response in a phase I trial

1 reference

12 December 2020

Modeling interpatient pharmacodynamic variability of etoposide.

1 reference

12 December 2020

Human pharmacokinetics, excretion, and metabolism of the anthracycline antibiotic menogaril (7-OMEN, NSC 269148) and their correlation with clinical toxicities

1 reference

12 December 2020

Relationship between 5-fluorouracil (5-FU) dose intensity and therapeutic response in patients with advanced colorectal cancer receiving infusional therapy containing 5-FU

1 reference

12 December 2020

Pharmacokinetics of paclitaxel and carboplatin in a dose-escalating and dose-sequencing study in patients with non-small-cell lung cancer. The European Cancer Centre

1 reference

12 December 2020

The use of population pharmacokinetics in drug development

1 reference

12 December 2020

Dose intensity of carboplatin in combination with cyclophosphamide or ifosfamide

1 reference

12 December 2020

Letter: Creatinine clearance: bedside estimate.

1 reference

12 December 2020

A limited sampling strategy for cyclophosphamide pharmacokinetics.

1 reference

12 December 2020

A sequential Bayesian algorithm for dose individualisation of carboplatin

1 reference

12 December 2020

Dose-effect study of carboplatin in ovarian cancer: a Danish Ovarian Cancer Group study.

1 reference

12 December 2020

Pharmacokinetics of anticancer agents in patients with impaired liver function

1 reference

12 December 2020

Clinical pharmacological studies of concurrent infusion of 5-fluorouracil and thymidine in treatment of colorectal carcinomas

1 reference

12 December 2020

Long-term weekly treatment of colorectal metastatic cancer with fluorouracil and leucovorin: results of a multicentric prospective trial of fluorouracil dosage optimization by pharmacokinetic monitoring in 152 patients

1 reference

12 December 2020

Pharmacokinetics of busulfan: correlation with veno-occlusive disease in patients undergoing bone marrow transplantation

1 reference

12 December 2020

Phase I study and pharmacokinetics of menogaril (NSC 269148) in patients with hepatic dysfunction.

1 reference

12 December 2020

A single-sample assay for the estimation of the area under the free carboplatin plasma concentration versus time curve

1 reference

12 December 2020

Evaluation of carboplatin pharmacokinetics in the absence and presence of paclitaxel

1 reference

12 December 2020

A randomized study of epirubicin at four different dose levels in advanced breast cancer. Feasibility of myelotoxicity prediction through single blood-sample measurement.

1 reference

12 December 2020

A single 24-hour plasma sample does not predict the carboplatin AUC from carboplatin-paclitaxel combinations or from a high-dose carboplatin-thiotepa-cyclophosphamide regimen.

1 reference

12 December 2020

Effectiveness of carboplatin, etoposide, and bleomycin combination chemotherapy in good-prognosis metastatic testicular nonseminomatous germ cell tumors

1 reference

12 December 2020

Oral idarubicin pharmacokinetics--correlation of trough level with idarubicin area under curve

1 reference

12 December 2020

Continuous carboplatin infusion during 6 weeks' radiotherapy in locally inoperable non-small-cell lung cancer: a phase I and pharmacokinetic study.

1 reference

12 December 2020

Relationship between pharmacokinetics of unchanged cisplatin and nephrotoxicity after intravenous infusions of cisplatin to cancer patients

1 reference

12 December 2020

Clinical pharmacokinetics and dose optimisation of carboplatin.

1 reference

12 December 2020

Serum creatinine as an index of renal function: new insights into old concepts.

1 reference

12 December 2020

Carboplatin dose in combination chemotherapy for testicular cancer

1 reference

12 December 2020

Prediction of carboplatin clearance from standard morphological and biological patient characteristics

1 reference

12 December 2020

Clinical pharmacodynamics of continuous-infusion etoposide

1 reference

12 December 2020

A novel pharmacodynamically based approach to dose optimization of carboplatin when used in combination with etoposide

1 reference

12 December 2020

Carboplatin dosage: prospective evaluation of a simple formula based on renal function

1 reference

12 December 2020

Phase II study with docetaxel (Taxotere) in advanced soft tissue sarcomas of the adult. EORTC Soft Tissue and Bone Sarcoma Group

1 reference

12 December 2020

Individual 5FU-dose adaptation schedule using bimonthly pharmacokinetically modulated LV5FU2 regimen: a feasibility study in patients with advanced colorectal cancer

1 reference

12 December 2020

Overview of recent topics in clinical pharmacology of anticancer agents

1 reference

12 December 2020

Renal handling of carboplatin

1 reference

12 December 2020

Paclitaxel and carboplatin in combination in the treatment of advanced non-small-cell lung cancer: a phase II toxicity, response, and survival analysis

1 reference

12 December 2020

Differences in teniposide disposition and pharmacodynamics in patients with newly diagnosed and relapsed acute lymphocytic leukemia

1 reference

12 December 2020

Phase I and pharmacologic study of hexamethylene bisacetamide in patients with advanced cancer

1 reference

12 December 2020

Relationships between carboplatin exposure and tumor response and toxicity in patients with ovarian cancer

1 reference

12 December 2020

Etoposide pharmacokinetics in children: the development and prospective validation of a dosing equation.

1 reference

12 December 2020

Pharmacokinetics and dosage reduction of cis-diammine(1,1-cyclobutanedicarboxylato)platinum in patients with impaired renal function

1 reference

12 December 2020

Creatinine clearance as a predictor of ultrafilterable platinum disposition in cancer patients treated with cisplatin: relationship between peak ultrafilterable platinum plasma levels and nephrotoxicity

1 reference

12 December 2020

Re: prediction of carboplatin clearance from standard morphological and biological patient characteristics

1 reference

12 December 2020

Phase I/pharmacokinetic study of topotecan by 24-hour continuous infusion weekly

1 reference

12 December 2020

Practical treatment guide for dose individualisation in cancer chemotherapy

1 reference

12 December 2020

Evaluation of platinum-DNA adduct levels relative to known prognostic variables in a cohort of ovarian cancer patients

1 reference

12 December 2020

High-dose methotrexate: Preliminary evaluation of a pharmacokinetic approach

1 reference

12 December 2020

Approaches to optimal dosing of hexamethylene bisacetamide

1 reference

12 December 2020

Pharmacodynamics of fluorouracil-based induction chemotherapy in advanced head and neck cancer

1 reference

12 December 2020

The measurement of cisplatin-DNA adduct levels in testicular cancer patients

1 reference

12 December 2020

Phase I study of paclitaxel as a 3-hour infusion followed by carboplatin in untreated patients with stage IV non-small cell lung cancer.

1 reference

12 December 2020

Phase II study of topotecan in patients with extensive-stage small-cell carcinoma of the lung: an Eastern Cooperative Oncology Group Trial

1 reference

12 December 2020

A clinical and pharmacokinetic study of high-dose carboplatin, paclitaxel, granulocyte colony-stimulating factor, and peripheral blood stem cells in patients with unresectable or metastatic cancer

1 reference

12 December 2020

Use of Plasma Pharmacokinetics to Predict and Prevent Methotrexate Toxicity

1 reference

12 December 2020

Pharmacodynamics of three daily infusions of etoposide in patients with extensive-stage small-cell lung cancer

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of topotecan given on a daily-times-five schedule in phase II clinical trials using a limited-sampling procedure

1 reference

12 December 2020

Phase II studies of 4'-iodo-4'-deoxydoxorubicin in advanced non-small cell lung, colon and breast cancers

1 reference

12 December 2020

Optimal sampling times for pharmacokinetic experiments

1 reference

12 December 2020

A pharmacologically guided phase I study of carboplatin in combination with methotrexate and vinblastine in advanced urothelial cancer.

1 reference

12 December 2020

Clinical pharmacology of oral and intravenous 4-demethoxydaunorubicin

1 reference

12 December 2020

A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer

1 reference

12 December 2020

Dose-toxicity relationship of carboplatin in combination with cyclophosphamide in ovarian cancer patients

1 reference

12 December 2020

10.2165/00003088-200039050-00004

Identifiers

DOI

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Dimensions Publication ID

31 July 2017

1006146183

0 references

Fatcat ID

release_ejyoicjdbndlhglurhbn6n6wxu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ejyoicjdbndlhglurhbn6n6wxu

24 November 2022

mapped directly with Wikidata item

1 reference