(Q34100188)

31 July 2017

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title

The use of microdialysis in CNS drug delivery studies. Pharmacokinetic perspectives and results with analgesics and antiepileptics (English)

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31 July 2017

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Hammarlund-Udenaes M

1

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31 July 2017

language of work or name

English

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publication date

1 December 2000

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Advanced Drug Delivery Reviews

31 July 2017

published in

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31 July 2017

volume

45

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31 July 2017

issue

2-3

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31 July 2017

page(s)

283-294

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Rationale for influx enhancement versus efflux blockade to increase drug exposure to the brain

31 July 2017

cites work

1 reference

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7 January 2021

Drug metabolizing enzymes in the brain and cerebral microvessels

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7 January 2021

Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs.

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7 January 2021

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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7 January 2021

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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7 January 2021

Expression of multidrug resistance-associated protein (MRP) in brain microvessel endothelial cells.

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7 January 2021

Kinetics of the multidrug transporter (P-glycoprotein) and its reversal

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7 January 2021

Analysis of zidovudine distribution to specific regions in rabbit brain using microdialysis

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7 January 2021

The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach.

1 reference

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7 January 2021

Drug equilibration across the blood-brain barrier--pharmacokinetic considerations based on the microdialysis method

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7 January 2021

Blood-brain barrier equilibration of codeine in rats studied with microdialysis

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7 January 2021

Gabapentin anticonvulsant action in rats: disequilibrium with peak drug concentrations in plasma and brain microdialysate

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7 January 2021

Fluconazole distribution to the brain: a crossover study in freely-moving rats using in vivo microdialysis

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7 January 2021

Elevated concentrations of morphine 6-beta-D-glucuronide in brain extracellular fluid despite low blood-brain barrier permeability

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7 January 2021

Nonlinear distribution of atenolol between plasma and cerebrospinal fluid

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7 January 2021

The unit impulse response procedure for the pharmacokinetic evaluation of drug entry into the central nervous system

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7 January 2021

Critical factors of intracerebral microdialysis as a technique to determine the pharmacokinetics of drugs in rat brain.

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7 January 2021

THE PERMEABILITY OF CAPILLARIES IN VARIOUS ORGANS AS DETERMINED BY USE OF THE 'INDICATOR DIFFUSION' METHOD.

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7 January 2021

Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard

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7 January 2021

Methods for Quantifying the transport of drugs across brain barrier systems

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7 January 2021

Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes

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7 January 2021

Simultaneous measurement of extracellular morphine and serotonin in brain tissue and CSF by microdialysis in awake rats

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7 January 2021

Relationship between morphine analgesia and cortical extracellular fluid levels of morphine and its metabolites in the rat: a microdialysis study

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7 January 2021

The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice.

1 reference

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7 January 2021

Evidence for P-glycoprotein-modulated penetration of morphine-6-glucuronide into brain capillary endothelium

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7 January 2021

Carbamazepine pharmacokinetics-pharmacodynamics in genetically epilepsy-prone rats

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7 January 2021

Measurement of carbamazepine and carbamazepine epoxide in the human brain using in vivo microdialysis

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7 January 2021

Phenytoin concentrations in the human brain: an in vivo microdialysis study

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7 January 2021

Potential use of microdialysis in pharmacokinetics: a protein binding study

1 reference

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7 January 2021

Estimation of topiramate in subdural cerebrospinal fluid, subcutaneous extracellular fluid, and plasma: a single case microdialysis study.

1 reference

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7 January 2021

The extracellular concentration of the anti-epileptic drug valproate in the rat brain as determined with microdialysis and an automated HPLC procedure

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2800%2900109-5

7 January 2021

Study on brain interstitial fluid distribution and blood-brain barrier transport of baclofen in rats by microdialysis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2800%2900109-5

7 January 2021

Investigation of the distribution of EAB 515 to cortical ECF and CSF in freely moving rats utilizing microdialysis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2800%2900109-5

7 January 2021

Modeling the route of administration-based enhancement in the brain delivery of EAB 515, studied by microdialysis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2800%2900109-5

7 January 2021

Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2800%2900109-5

7 January 2021

10.1016/S0169-409X(00)00109-5

Identifiers

DOI

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release_rnllgsp72bejlnnkrnvriyy5eu

31 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rnllgsp72bejlnnkrnvriyy5eu

24 November 2022

mapped directly with Wikidata item

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