(Q34105915)

31 July 2017

SH2-B family members differentially regulate JAK family tyrosine kinases (English)

1 reference

31 July 2017

Karen B O'Brien

1

1 reference

31 July 2017

John J O'Shea

series ordinal

2

1 reference

31 July 2017

Christin Carter-Su

series ordinal

3

1 reference

31 July 2017

language of work or name

English

0 references

publication date

18 December 2001

1 reference

Journal of Biological Chemistry

31 July 2017

1 reference

31 July 2017

277

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31 July 2017

8673-8681

1 reference

31 July 2017

10

1 reference

Janus kinases and their role in growth and disease

31 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Partial impairment of cytokine responses in Tyk2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Cytokine signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Neuronal differentiation factors/cytokines and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

STATs and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Growth Hormone-promoted Tyrosyl Phosphorylation of SHC Proteins and SHC Association with Grb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

The yeast tribrid system--genetic detection of trans-phosphorylated ITAM-SH2-interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Identification and characterization of novel substrates of Trk receptors in developing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Growth hormone (GH) stimulates protein synthesis in cells transfected with GH receptor complementary DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

High-efficiency transformation of mammalian cells by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Growth hormone induces c-fos and c-jun expression in cells with varying requirements for differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

APS, an adapter protein with a PH and SH2 domain, is a substrate for the insulin receptor kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Identification of the APS protein as a novel insulin receptor substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Regulation of the Jak2 tyrosine kinase by its pseudokinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Jaks and Stats in signaling by the cytokine receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

SH2-B and APS are multimeric adapters that augment TrkA signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Differential substrate recognition capabilities of Janus family protein tyrosine kinases within the interleukin 2 receptor (IL2R) system: Jak3 as a potential molecular target for treatment of leukemias with a hyperactive Jak-Stat signaling machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

A STAT factor mediates the sexually dimorphic regulation of hepatic cytochrome P450 3A10/lithocholic acid 6 beta-hydroxylase gene expression by growth hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/Stat 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Growth hormone induces insulin-like growth factor-I gene transcription by a synergistic action of STAT5 and HNF-1alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Growth hormone-mediated regulation of insulin-like growth factor I promoter activity in C6 glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Cbl: many adaptations to regulate protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109165200

21 January 2018

Identifiers

DOI

10.1074/JBC.M109165200

1 reference

31 July 2017

1 reference