(Q34106393)

English

Unraveling the convoluted biological roles of type I interferons in infection and immunity: a way forward for therapeutics and vaccine design

scientific article

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scholarly article

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Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

Unraveling the convoluted biological roles of type I interferons in infection and immunity: a way forward for therapeutics and vaccine design (English)

1 reference

Europe PubMed Central

31 July 2017

vaccine engineering

1 reference

based on heuristic

inferred from title

Danushka Wijesundara

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Yang Xi

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Charani Ranasinghe

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

publication date

29 August 2014

1 reference

Europe PubMed Central

31 July 2017

Frontiers in Immunology

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

412

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Type I interferon signals in macrophages and dendritic cells control dengue virus infection: implications for a new mouse model to test dengue vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Alpha/beta interferon receptor signaling amplifies early proinflammatory cytokine production in the lung during respiratory syncytial virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Plasmacytoid dendritic cell dynamics tune interferon-alfa production in SIV-infected cynomolgus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Type I interferons promote severe disease in a mouse model of lethal ehrlichiosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

STING-dependent type I IFN production inhibits cell-mediated immunity to Listeria monocytogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

1 reference

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5 July 2018

Regulation of type I interferon responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Low dose of interferon-α improves the clinical outcomes of docetaxel in patients with castration-resistant prostate cancer: A pilot study

1 reference

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5 July 2018

Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung

1 reference

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5 July 2018

Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation

1 reference

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5 July 2018

HIV-1 evades innate immune recognition through specific cofactor recruitment

1 reference

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5 July 2018

Confounding roles for type I interferons during bacterial and viral pathogenesis

1 reference

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5 July 2018

Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection

1 reference

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5 July 2018

Innate immune evasion strategies by human immunodeficiency virus type 1.

1 reference

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5 July 2018

Type I IFN inhibits innate IL-10 production in macrophages through histone deacetylase 11 by downregulating microRNA-145.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

IFN-ε is constitutively expressed by cells of the reproductive tract and is inefficiently secreted by fibroblasts and cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Persistent LCMV infection is controlled by blockade of type I interferon signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses

1 reference

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5 July 2018

Interferon-ε protects the female reproductive tract from viral and bacterial infection

1 reference

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5 July 2018

Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration

1 reference

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5 July 2018

Type I interferon induction during influenza virus infection increases susceptibility to secondary Streptococcus pneumoniae infection by negative regulation of γδ T cells

1 reference

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5 July 2018

Role of novel type I interferon epsilon in viral infection and mucosal immunity.

1 reference

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5 July 2018

Dynamic roles of type I and type II IFNs in early infection with Mycobacterium tuberculosis

1 reference

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5 July 2018

Type I IFN drives a distinctive dendritic cell maturation phenotype that allows continued class II MHC synthesis and antigen processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Type 1 interferons and antiviral CD8 T-cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Type I IFN promotes IL-10 production from T cells to suppress Th17 cells and Th17-associated autoimmune inflammation

1 reference

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5 July 2018

Hazara virus infection is lethal for adult type I interferon receptor-knockout mice and may act as a surrogate for infection with the human-pathogenic Crimean-Congo hemorrhagic fever virus

1 reference

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5 July 2018

The type I interferon system in the etiopathogenesis of autoimmune diseases

1 reference

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5 July 2018

Overactivation of plasmacytoid dendritic cells inhibits antiviral T-cell responses: a model for HIV immunopathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

1 reference

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5 July 2018

IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity

1 reference

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5 July 2018

Type I interferon: friend or foe?

1 reference

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5 July 2018

Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections

1 reference

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5 July 2018

Essential role of mitochondrial antiviral signaling, IFN regulatory factor (IRF)3, and IRF7 in Chlamydophila pneumoniae-mediated IFN-beta response and control of bacterial replication in human endothelial cells

1 reference

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5 July 2018

Plasmacytoid dendritic cells in HIV infection: striking a delicate balance

1 reference

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5 July 2018

Type I interferons: crucial participants in disease amplification in autoimmunity

1 reference

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5 July 2018

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

1 reference

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5 July 2018

Impaired interferon signaling is a common immune defect in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Type I interferon signaling exacerbates Chlamydia muridarum genital infection in a murine model

1 reference

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5 July 2018

Differential effects of the type I interferons alpha4, beta, and epsilon on antiviral activity and vaccine efficacy

1 reference

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5 July 2018

The interferon response inhibits HIV particle production by induction of TRIM22

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5 July 2018

Signal 3 availability limits the CD8 T cell response to a solid tumor

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5 July 2018

The interferons: 50 years after their discovery, there is much more to learn

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5 July 2018

Rhesus monkey TRIM5alpha restricts HIV-1 production through rapid degradation of viral Gag polyproteins

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5 July 2018

HIV-1 gp120 inhibits TLR9-mediated activation and IFN-{alpha} secretion in plasmacytoid dendritic cells

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5 July 2018

Differential receptor subunit affinities of type I interferons govern differential signal activation.

1 reference

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5 July 2018

Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses

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5 July 2018

Type I interferon in systemic lupus erythematosus and other autoimmune diseases

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5 July 2018

Exhaustion of type I interferon response following an acute viral infection

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5 July 2018

Type I IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus

2 references

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5 July 2018

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21 January 2018

Cyclophilin, TRIM5, and innate immunity to HIV-1

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5 July 2018

CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

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5 July 2018

Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15.

1 reference

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5 July 2018

Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity

1 reference

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5 July 2018

Restoring function in exhausted CD8 T cells during chronic viral infection

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5 July 2018

Type I interferons trigger systemic, partial lymphocyte activation in response to viral infection

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5 July 2018

TRIM family proteins: retroviral restriction and antiviral defence

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5 July 2018

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

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5 July 2018

Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B.

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5 July 2018

Plasmacytoid dendritic cells in immunity

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5 July 2018

Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes

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5 July 2018

Virus interference. I. The interferon

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5 July 2018

Antiviral activity of limitin against encephalomyocarditis virus, herpes simplex virus, and mouse hepatitis virus: diverse requirements by limitin and alpha interferon for interferon regulatory factor 1.

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5 July 2018

Pegylated interferon plus ribavirin for the treatment of chronic hepatitis C.

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5 July 2018

Endogenous and exogenous interferons in HIV-infection.

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5 July 2018

Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking

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5 July 2018

Chronic myeloid leukemia and interferon-alpha: a study of complete cytogenetic responders

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5 July 2018

Viruses and interferons

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

Type I interferons keep activated T cells alive

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5 July 2018

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5 July 2018

How cells respond to interferons

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5 July 2018

Are all type I human interferons equivalent?

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5 July 2018

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

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5 July 2018

Human interferon omega--a review.

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5 July 2018

Use of interferon-alpha in laryngeal papillomatosis: eight years of the Cuban national programme.

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5 July 2018

Interferon Therapy in Juvenile Laryngeal Papillomatosis

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5 July 2018

Interferon-induced inhibition of Chlamydia trachomatis: dissociation from antiviral and antiproliferative effects

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5 July 2018

Interferon therapy for condylomata acuminata

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5 July 2018

Treatment of recurrent respiratory papillomatosis with human leukocyte interferon. Results of a multicenter randomized clinical trial

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5 July 2018

Interferons in the treatment of genital human papillomavirus infections.

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5 July 2018

Interferons and their actions

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5 July 2018

Double-blind, placebo-controlled trial of human lymphoblastoid interferon prophylaxis of cytomegalovirus infection in renal transplant recipients

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5 July 2018

Human Leukocyte Interferon for the Treatment of Herpes Zoster in Patients with Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Prevention of Reactivated Herpes Simplex Infection by Human Leukocyte Interferon after Operation on the Trigeminal Root

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Topical therapy of ulcerative herpetic keratitis with human interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

5 July 2018

Virus interference. II. Some properties of interferon

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

IFN-tau: a novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Type I interferon signaling protects mice from lethal henipavirus infection.

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Effects of type I interferons on Friend retrovirus infection

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Role of type I and type II interferon responses in recovery from infection with an encephalitic flavivirus

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Low-level HIV infection of plasmacytoid dendritic cells: onset of cytopathic effects and cell death after PDC maturation

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

PD-1 ligands, negative regulators for activation of naive, memory, and recently activated human CD4+ T cells.

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B.

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Interferon-beta treatment increases human papillomavirus early gene transcription and viral plasmid genome replication by activating interferon regulatory factor (IRF)-1.

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (I

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Faldaprevir combined with pegylated interferon alfa-2a and ribavirin in treatment-naïve patients with chronic genotype 1 HCV: SILEN-C1 trial.

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Ligand-induced assembling of the type I interferon receptor on supported lipid bilayers.

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2014.00412

21 January 2018

Drug induced hypersensitivity syndrome by triple therapy of peginterferon alpha2b, ribavirin and telaprevir in patient with double positive for HBV and HCV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

28 October 2018

Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

28 October 2018

Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148647

9 December 2018

Antigen-specific activation thresholds of CD8+ T cells are independent of IFN-I-mediated partial lymphocyte activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I interferons produced by dendritic cells promote their phenotypic and functional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-alpha/beta enhances BCR-dependent B cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I Interferon Production Is Profoundly and Transiently Impaired in Primary HIV‐1 Infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced blood CD123+ (lymphoid) and CD11c+ (myeloid) dendritic cell numbers in primary HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human leukocyte interferon purified to homogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evaluation of immune system cell infiltrate in the cervical stroma of patients with grade III cervical intraepithelial neoplasia after treatment with intralesional alpha-2B interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of interferon-alpha on human warts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of CCR-7, MIP-3beta , and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I IFN as a natural adjuvant for a protective immune response: lessons from the influenza vaccine model

1 reference

https://pubmed.ncbi.nlm.nih.gov/25221557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FIMMU.2014.00412

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221557%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

ResearchGate publication ID

0 references

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