(Q34107213)

31 July 2017

title

Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein (English)

1 reference

G protein-coupled receptor

31 July 2017

main subject

0 references

PDZ domain containing 7

1 reference

Adhesion G protein-coupled receptor V1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Xiao Yu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962568%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Qiao-Xia Hu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962568%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jun-Hong Dong

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962568%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Hai-Bo Du

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962568%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Dao-Lai Zhang

4

1 reference

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9 June 2020

Hong-Ze Ren

5

1 reference

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9 June 2020

Ming-Liang Ma

6

1 reference

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9 June 2020

Yuan Cai

7

1 reference

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9 June 2020

Tong-Chao Zhao

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962568%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Xiao-Lei Yin

9

1 reference

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9 June 2020

Tian Xue

11

1 reference

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9 June 2020

Zhi-Gang Xu

12

1 reference

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9 June 2020

Jin-Peng Sun

13

1 reference

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9 June 2020

language of work or name

English

0 references

publication date

24 June 2014

1 reference

Journal of Biological Chemistry

31 July 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962568%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

289

1 reference

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9 June 2020

issue

35

1 reference

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9 June 2020

page(s)

24215-24225

1 reference

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describes a project that uses

9 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4148852/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

The very large G protein coupled receptor (Vlgr1) in hair cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Regulated vesicular trafficking of specific PCDH15 and VLGR1 variants in auditory hair cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Adhesion G protein-coupled receptors: signaling, pharmacology, and mechanisms of activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Role for a novel Usher protein complex in hair cell synaptic maturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Usher syndrome (sensorineural deafness and retinitis pigmentosa): pathogenesis, molecular diagnosis and therapeutic approaches

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Cell adhesion receptor GPR133 couples to Gs protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Crystal structure of the β2 adrenergic receptor-Gs protein complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

In vivo electroporation of developing mouse retina

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Studies on the very large G protein-coupled receptor: from initial discovery to determining its role in sensorineural deafness in higher animals.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

The very large G-protein-coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type II

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

A nonsense mutation of the MASS1 gene in a family with febrile and afebrile seizures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

A novel gene causing a mendelian audiogenic mouse epilepsy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

Cellular signaling by an agonist-activated receptor/Gs alpha fusion protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148852

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.549816

Enhanced G(i) signaling selectively negates beta2-adrenergic receptor (AR)--but not beta1-AR-mediated positive inotropic effect in myocytes from failing rat hearts

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.549816

21 January 2018

Identifiers

DOI

10.1074/JBC.M114.549816

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962568%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24962568%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference