(Q34109682)

English

Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice

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scholarly article

1 reference

Europe PubMed Central

31 July 2017

Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice (English)

1 reference

Europe PubMed Central

31 July 2017

author name string

J Quddus

1

1 reference

Europe PubMed Central

31 July 2017

K J Johnson

2

1 reference

Europe PubMed Central

31 July 2017

J Gavalchin

3

1 reference

Europe PubMed Central

31 July 2017

E P Amento

4

1 reference

Europe PubMed Central

31 July 2017

C E Chrisp

5

1 reference

Europe PubMed Central

31 July 2017

R L Yung

6

1 reference

Europe PubMed Central

31 July 2017

B C Richardson

7

1 reference

Europe PubMed Central

31 July 2017

language of work or name

0 references

publication date

1 July 1993

1 reference

Europe PubMed Central

31 July 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

31 July 2017

92

1 reference

Europe PubMed Central

31 July 2017

1

1 reference

Europe PubMed Central

31 July 2017

38-53

1 reference

Europe PubMed Central

31 July 2017

Spontaneous release of a factor with properties of T cell growth factor from a continuous line of primate tumor T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Drug-induced lupus: clinical and serological studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Ultraviolet radiation-induced metallothionein-I gene activation is associated with extensive DNA demethylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

The autologous mixed-lymphocyte reaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Prognostic factors in lupus nephritis. Contribution of renal histologic data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Allosuppressor- and allohelper-T cells in acute and chronic graft-vs.-host (GVH) disease. III. Different Lyt subsets of donor T cells induce different pathological syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

The implications of procainamide metabolism to its induction of lupus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

The Immunology and Pathology of NZB Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

The regulatory role of macrophages in antigenic stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Biological effects of 5-azacytidine in eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Increased immunoglobulin response to gamma-interferon by lymphocytes from patients with systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Effect of cyclosporin A, silica quartz dust, and protease inhibitors on virus-induced demyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

The recombinant 65-kD heat shock protein of Mycobacterium bovis Bacillus Calmette-Guerin/M. tuberculosis is a target molecule for CD4+ cytotoxic T lymphocytes that lyse human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Heterogeneity of cytokine secretion patterns and functions of helper T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Acquisition of immunologic self-tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Isolation of CD4- CD8- mycobacteria-reactive T lymphocyte clones from rheumatoid arthritis synovial fluid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

N-acetylprocainamide is a less potent inducer of T cell autoreactivity than procainamide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Biochemistry of azacitidine: a review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Procainamide inhibits DNA methyltransferase in a human T cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

CD8+ lymphocytes from patients with systemic lupus erythematosus sustain, rather than suppress, spontaneous polyclonal IgG production and synergize with CD4+ cells to support autoantibody synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Bcl-2 maintains B cell memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

IL-4 plays a dominant role in the differential development of Tho into Th1 and Th2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

5-Azacytidine Hydrolysis Kinetics Measured by High-Pressure Liquid Chromatography and 13C-NMR Spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

Drug-induced systemic lupus erythematosus: A critical review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=293525

5 July 2018

CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of graft versus host-associated immunodeficiency by CD4+ T cell clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative changes in T cell DNA methylation occur during differentiation and ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Azacytidine inhibits the lpr gene-induced lymphadenopathy and acceleration of lupus-like syndrome in MRL/MpJ-lpr/lpr mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of B cell growth in systemic lupus erythematosus. Effects of recombinant 12-kDa B cell growth factor, interleukin 4 and transforming growth factor-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of lysis by cytotoxic T lymphocyte clones. Lytic activity and gene expression in cloned antigen-specific CD4+ and CD8+ T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of macrophages in the induction of antibody in x-irradiated animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lupus nephritis. Clinical course as related to morphologic forms and their transitions

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The comparative effects of 5-azacytidine and dihydro-5-azacytidine on 4 S and 5 S nuclear RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): mechanism of blockade of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lupus prone (SWR x NZB)F1 mice produce potentially nephritogenic autoantibodies inherited from the normal SWR parent

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine models of systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of an inhibitor of DNA methylation on T cells. I. 5-Azacytidine induces T4 expression on T8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducer T-cell-mediated killing of antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of an inhibitor of DNA methylation on T cells. II. 5-Azacytidine induces self-reactivity in antigen-specific T4+ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific lysis of Listeria monocytogenes-infected macrophages by class II-restricted L3T4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell tolerance by clonal elimination in the thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell repertoire

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen presenting function of class II MHC expressing pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ T cell-mediated killing of MHC class II-positive antigen-presenting cells. I. Characterization of target cell recognition by in vivo or in vitro activated CD4+ killer T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7686923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI116576

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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