(Q34113268)

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Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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author name string

Conner JM

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Darracq MA

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Roberts J

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Tuszynski MH

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

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publication date

1 February 2001

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

31 July 2017

98

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1941-1946

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Cortical cholinergic inputs mediating arousal, attentional processing and dreaming: differential afferent regulation of the basal forebrain by telencephalic and brainstem afferents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Activation of TrkA by nerve growth factor upregulates expression of the cholinergic gene locus but attenuates the response to ciliary neurotrophic growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Trks: signal transduction and intracellular pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

The cholinergic deficit in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Feature article: are neurons lost from the primate cerebral cortex during normal aging?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Memory, language, and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Life and death of neurons in the aging brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Reduction in p140-TrkA Receptor Protein within the Nucleus Basalis and Cortex in Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Somatic gene transfer to the adult primate central nervous system:in vitroandin vivocharacterization of cells genetically modified to secrete nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Neocortical neuron number in humans: effect of sex and age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Cholinergic neurotransmission and synaptic plasticity concerning memory processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Decreased trkA gene expression within basal forebrain neurons in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Central cholinergic systems and cognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Intracellular signaling pathways activated by neurotrophic factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Characterization of antibodies to nerve growth factor: assay-dependent variability in the cross-reactivity with other neurotrophins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Therapeutic potential of neurotrophic factors for neurological disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Regionally specific loss of neurons in the aging human hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Acetylcholine synthesis and release following continuous intracerebral administration of NGF in adult and aged Fischer-344 rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

NGF and the local control of nerve terminal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Somatic gene transfer of NGF to the aged brain: behavioral and morphological amelioration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Reversal of age-dependent cognitive impairments and cholinergic neuron atrophy by NGF-secreting neural progenitors grafted to the basal forebrain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Nerve growth factor in Alzheimerʼs disease: defective retrograde transport to nucleus basalis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata), and hypothalamus in the rhesus monkey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Age-related changes in multiple neurotransmitter systems in the monkey brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Spatial memory deficits in aged rats: contributions of the cholinergic system assessed by ChAT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Exogenous nerve growth factor increases the activity of high-affinity choline uptake and choline acetyltransferase in brain of Fisher 344 male rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Markers for biogenic amines in the aged rat brain: relationship to decline in spatial learning ability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Recombinant human nerve growth factor infusions prevent cholinergic neuronal degeneration in the adult primate brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Local control of neurite development by nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

5 July 2018

Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

Unbiased stereological estimation of the number of neurons in the human hippocampus

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

Age-related neuronal loss from the substantia nigra-pars compacta and ventral tegmental area of the rhesus monkey.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

The effect of aging on pars compacta of the substantia nigra in rhesus monkey

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

Neurotropism of nerve growth factor for adult rat septal cholinergic axons in vivo

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

A modified histochemical technique to visualize acetylcholinesterase-containing axons

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

Severe learning impairment caused by combined immunotoxic lesion of the cholinergic projections to the cortex and hippocampus in monkeys

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

Systematic regional variations in the loss of cortical cholinergic fibers in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

Synaptic loss in cognitively impaired aged rats is ameliorated by chronic human nerve growth factor infusion

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

NGF mRNA is not decreased in frontal cortex from Alzheimer's disease patients.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1941

21 January 2018

Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

28 October 2018

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

28 October 2018

Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

28 October 2018

Human nerve growth factor improves spatial memory in aged but not in young rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

28 October 2018

Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

28 October 2018

Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29361

28 October 2018

Nerve growth factor and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11172055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cognitive functions of cortical acetylcholine: toward a unifying hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11172055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11172055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11172055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.98.4.1941

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2001PNAS...98.1941C

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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