(Q34114595)

31 July 2017

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title

Molecular farming of pharmaceutical proteins (English)

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31 July 2017

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Fischer R

1

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PubMed ID

11131007

31 July 2017

Emans N

series ordinal

2

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31 July 2017

1 January 2000

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31 July 2017

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31 July 2017

9

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31 July 2017

279-99; discussion 277

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31 July 2017

4-5

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https://scigraph.springernature.com/pub.10.1023/a:1008975123362

31 July 2017

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cites work

Production of functional human alpha 1-antitrypsin by plant cell culture

1 reference

12 December 2020

Determination of the pore size of cell walls of living plant cells.

1 reference

12 December 2020

Antigens produced in plants by infection with chimeric plant viruses immunize against rabies virus and HIV-1.

1 reference

12 December 2020

Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single-chain Fv epitopes in tobacco plants

1 reference

12 December 2020

Plant cell suspension cultures: some engineering considerations

1 reference

12 December 2020

Production of a diagnostic monoclonal antibody in perennial alfalfa plants

1 reference

12 December 2020

Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene

1 reference

12 December 2020

Transformation of rice mediated by Agrobacterium tumefaciens

1 reference

12 December 2020

Rapid production of single-chain Fv fragments in plants using a potato virus X episomal vector

1 reference

12 December 2020

Plant virus gene vectors for transient expression of foreign proteins in plants

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12 December 2020

Production of secretory immunoglobulin A by a single mammalian cell

1 reference

12 December 2020

Towards molecular farming in the future: using plant-cell-suspension cultures as bioreactors.

1 reference

12 December 2020

Nicotiana benthamiana plants expressing beet necrotic yellow vein virus (BNYVV) coat protein-specific scFv are partially protected against the establishment of the virus in the early stages of infection and its pathogenic effects in the late stages

1 reference

12 December 2020

Expression of a chemically synthesized gene for human epidermal growth factor under the control of cauliflower mosaic virus 35S promoter in transgenic tobacco

1 reference

12 December 2020

Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice

1 reference

12 December 2020

Characterization of a human glycoprotein (erythropoietin) produced in cultured tobacco cells

1 reference

12 December 2020

Synthesis and self-assembly of a functional monoclonal antibody in transgenic Nicotiana tabacum

1 reference

12 December 2020

Secretion of biologically active human interleukin-2 and interleukin-4 from genetically modified tobacco cells in suspension culture.

1 reference

12 December 2020

Compartment-specific accumulation of recombinant immunoglobulins in plant cells: an essential tool for antibody production and immunomodulation of physiological functions and pathogen activity

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12 December 2020

Cultivation of plant cells in a stirred vessel: effect of impeller design

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12 December 2020

Improving scFv antibody expression levels in the plant cytosol

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12 December 2020

Antibodies produced in plants

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12 December 2020

Agrobacterium-mediated production of transgenic rice plants expressing a chimeric alpha-amylase promoter/beta-glucuronidase gene.

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12 December 2020

Assembly of an antibody and its derived antibody fragment in Nicotiana and Arabidopsis.

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12 December 2020

Use of viral replicons for the expression of genes in plants

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12 December 2020

High-level production and long-term storage of engineered antibodies in transgenic tobacco seeds.

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12 December 2020

Making antibodies by phage display technology

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12 December 2020

Production and purification of two recombinant proteins from transgenic corn

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12 December 2020

Characterization and applications of antibodies produced in plants

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12 December 2020

Optimization of scFv antibody production in transgenic plants

1 reference

12 December 2020

High-yield production of a human therapeutic protein in tobacco chloroplasts

1 reference

12 December 2020

The expression, localization, and effect of a human interferon in plants

1 reference

12 December 2020

Recombinant proteins from transgenic plants.

1 reference

12 December 2020

Immunotherapeutic potential of antibodies produced in plants

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12 December 2020

Affinity-purification of a TMV-specific recombinant full-size antibody from a transgenic tobacco suspension culture

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12 December 2020

Human haemoglobin from transgenic tobacco

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12 December 2020

Secretion of a functional single-chain Fv protein in transgenic tobacco plants and cell suspension cultures

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12 December 2020

Controlling gene expression in transgenics

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12 December 2020

Costimulation of T-cell proliferation by a chimeric B7-antibody fusion protein

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12 December 2020

Oral immunization with a recombinant bacterial antigen produced in transgenic plants.

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12 December 2020

Bacterial and plant-produced scFv proteins have similar antigen-binding properties.

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12 December 2020

Expression and characterization of bispecific single-chain Fv fragments produced in transgenic plants

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12 December 2020

Malarial epitopes expressed on the surface of recombinant tobacco mosaic virus

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12 December 2020

Purification of monoclonal antibodies by epitope and mimotope affinity chromatography

1 reference

12 December 2020

Expression of the rabies virus glycoprotein in transgenic tomatoes

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12 December 2020

Generation and assembly of secretory antibodies in plants

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12 December 2020

Transient expression of a tumor-specific single-chain fragment and a chimeric antibody in tobacco leaves

1 reference

12 December 2020

The development of cowpea mosaic virus as a potential source of novel vaccines

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12 December 2020

Phage-displayed peptide libraries

1 reference

12 December 2020

Changes in protein methylation associated with the elicitation response in cell cultures of alfalfa (Medicago sativaL.)

1 reference

12 December 2020

Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies

1 reference

12 December 2020

Assembly of monoclonal antibodies with IgG1 and IgA heavy chain domains in transgenic tobacco plants

1 reference

12 December 2020

The C-terminal KDEL sequence increases the expression level of a single-chain antibody designed to be targeted to both the cytosol and the secretory pathway in transgenic tobacco

1 reference

12 December 2020

Expression of hepatitis B surface antigen in transgenic plants

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12 December 2020

Plants as bioreactors for biopharmaceuticals: regulatory considerations.

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12 December 2020

Expression of human muscarinic cholinergic receptors in tobacco.

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12 December 2020

Regulatory agency concerns in the manufacturing and testing of monoclonal antibodies for therapeutic use.

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12 December 2020

Presentation of heterologous peptides on plant viruses: genetics, structure, and function

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12 December 2020

Functional expression in bacteria and plants of an scFv antibody fragment against tospoviruses.

1 reference

12 December 2020

Rapid, high-level expression of glycosylated rice alpha-amylase in transfected plants by an RNA viral vector

1 reference

12 December 2020

Plant expression systems for the production of vaccines

1 reference

12 December 2020

Transient gene expression in electroporated protoplasts and intact cells of sugar beet

1 reference

12 December 2020

High efficiency transformation of cultured tobacco cells.

1 reference

12 December 2020

Expanded bed protein A affinity chromatography of a recombinant humanized monoclonal antibody: process development, operation, and comparison with a packed bed method

1 reference

12 December 2020

Expression of alpha-amylases, carbohydrate metabolism, and autophagy in cultured rice cells is coordinately regulated by sugar nutrient

1 reference

12 December 2020

Vectors based on maize streak virus can replicate to high copy numbers in maize plants.

1 reference

12 December 2020

Bacterial expression of immunoglobulin fragments

1 reference

12 December 2020

Recombinant protein production in transgenic animals

1 reference

12 December 2020

The expression of a nopaline synthase ? human growth hormone chimaeric gene in transformed tobacco and sunflower callus tissue

1 reference

12 December 2020

Protective immune response to foot-and-mouth disease virus with VP1 expressed in transgenic plants.

1 reference

12 December 2020

Production of monoclonal antibody in plants.

1 reference

12 December 2020

Expression and assembly of a full-length monoclonal antibody in plants using a plant virus vector

1 reference

12 December 2020

Plant-derived vaccine protects target animals against a viral disease

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12 December 2020

1 reference

12 December 2020

'Phytoantibodies': a general vector for the expression of immunoglobulin domains in transgenic plants.

1 reference

12 December 2020

Large-scale insect and plant cell culture

1 reference

12 December 2020

Expression of single-chain antibody fragments (scFv) specific for beet necrotic yellow vein virus coat protein or 25 kDa protein in Escherichia coli and Nicotiana benthamiana

1 reference

12 December 2020

Antibody production in transgenic plants

1 reference

12 December 2020

Expression and characterization of bryodin 1 and a bryodin 1-based single-chain immunotoxin from tobacco cell culture

1 reference

12 December 2020

Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance

1 reference

12 December 2020

Induction of a protective antibody response to foot and mouth disease virus in mice following oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1.

1 reference

12 December 2020

Production of correctly processed human serum albumin in transgenic plants

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12 December 2020

Production of antibodies in transgenic plants

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12 December 2020

Production of antibodies in transgenic plants

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12 December 2020

Heterologous protein production in transgenic plants

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12 December 2020

A plant-derived edible vaccine against hepatitis B virus.

1 reference

12 December 2020

Development of biopharmaceuticals in plant expression systems: cloning, expression and immunological reactivity of human cytomegalovirus glycoprotein B (UL55) in seeds of transgenic tobacco

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12 December 2020

Transgenic plants as vaccine production systems

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12 December 2020

Correlation betweenin VitroStability andin VivoPerformance of Anti-GCN4 Intrabodies as Cytoplasmic Inhibitors

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12 December 2020

Efficient transformation of rice (Oryza sativa L.) mediated by Agrobacterium and sequence analysis of the boundaries of the T-DNA.

1 reference

12 December 2020

Apoplastic and cytosolic expression of full-size antibodies and antibody fragments in Nicotiana tabacum.

1 reference

12 December 2020

Polypeptides of hepatitis B surface antigen produced in transgenic potato

1 reference

12 December 2020

Production of biologically active hirudin in plant seeds using oleosin partitioning

1 reference

12 December 2020

Analysis of the N-glycosylation of recombinant glycoproteins produced in transgenic plants

1 reference

12 December 2020

N-Glycosylation of a mouse IgG expressed in transgenic tobacco plants

1 reference

12 December 2020

A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpes

1 reference

12 December 2020

1 reference

12 December 2020

Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack

1 reference

12 December 2020

A plant-based cholera toxin B subunit-insulin fusion protein protects against the development of autoimmune diabetes

1 reference

12 December 2020

Expression of a single-chain Fv antibody against abscisic acid creates a wilty phenotype in transgenic tobacco

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12 December 2020

Production of recombinant proteins in plant root exudates

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12 December 2020

Seed-specific immunomodulation of abscisic acid activity induces a developmental switch

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12 December 2020

Stable accumulation of Aspergillus niger phytase in transgenic tobacco leaves

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12 December 2020

FDA perspective on specifications for biotechnology products--from IND to PLA.

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12 December 2020

A simple and general method for transferring genes into plants

1 reference

12 December 2020

Production of a foreign protein product with genetically modified plant cells

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12 December 2020

Plant antibodies for immunotherapy

1 reference

12 December 2020

Rice cell culture as an alternative production system for functional diagnostic and therapeutic antibodies

1 reference

12 December 2020

Coordinate expression of antibody subunit genes yields high levels of functional antibodies in roots of transgenic tobacco.

1 reference

12 December 2020

Bioproduction of human enzymes in transgenic tobacco

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12 December 2020

Efficacy of a food plant-based oral cholera toxin B subunit vaccine

1 reference

12 December 2020

Engineering of a single-chain variable-fragment (scFv) antibody specific for the stolbur phytoplasma (Mollicute) and its expression in escherichia coli and tobacco plants

1 reference

12 December 2020

Taxol (paclitaxel) production using free and immobilized cells of Taxus cuspidata

1 reference

12 December 2020

Elicitor-induced generation of active oxygen in suspension cultures of Arabidopsis thaliana

1 reference

12 December 2020

Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

12 December 2020

High level accumulation of single-chain variable fragments in the cytosol of transgenic Petunia hybrida.

1 reference

12 December 2020

Co-introduction of an antisense gene for an endogenous seed storage protein can increase expression of a transgene in Arabidopsis thaliana seeds.

1 reference

12 December 2020

Assembly of antibodies and mutagenized variants in transgenic plants and plant cell cultures

1 reference

12 December 2020

Towards molecular farming in the future: moving from diagnostic protein and antibody production in microbes to plants.

1 reference

12 December 2020

Immunization against rabies with plant-derived antigen

1 reference

12 December 2020

Subcellular targeting and purification of recombinant proteins in plant production systems

1 reference

12 December 2020

Production of recombinant proteins in transgenic plants: Practical considerations

1 reference

12 December 2020

Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato.

1 reference

12 December 2020

Validating the preparation of clinical monoclonal antibodies

1 reference

12 December 2020

Plants for delivery of edible vaccines

1 reference

12 December 2020

Establishment of a transgenic tobacco cell suspension culture system for producing murine granulocyte-macrophage colony stimulating factor

1 reference

12 December 2020

Affinity fusion strategies for detection, purification, and immobilization of recombinant proteins

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12 December 2020

Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans

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12 December 2020

Large-scale plant cell culture: methods, applications and products.

1 reference

12 December 2020

Molecular farming of industrial proteins from transgenic maize.

1 reference

12 December 2020

Isolation of erythropoietin receptor agonist peptides using evolved phage libraries

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12 December 2020

Biological therapy of ovarian cancer: current directions.

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12 December 2020

Synthesis of a functional anti-phytochrome single-chain Fv protein in transgenic tobacco

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1008975123362

1 reference

PubMed ID

11131007

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

11131007