(Q34118115)

31 July 2017

New drugs for the treatment of human African trypanosomiasis: research and development (English)

1 reference

31 July 2017

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African trypanosomiasis

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author name string

Keiser J

series ordinal

1

1 reference

PubMed ID

11137740

31 July 2017

Stich A

series ordinal

2

1 reference

PubMed ID

11137740

31 July 2017

Burri C

series ordinal

3

1 reference

31 July 2017

1 January 2001

1 reference

31 July 2017

Trends in Parasitology

1 reference

31 July 2017

17

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31 July 2017

1

1 reference

31 July 2017

42-49

1 reference

Mel B in the treatment of human trypanosomiasis

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

From genome to drug--optimising the drug discovery process

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Antitrypanosomal activity of a new triazine derivative, SIPI 1029, In vitro and in model infections

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Effect of megazol on Trypanosoma brucei brucei acute and subacute infections in Swiss mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Mutagenicity of CL 64855, a potent anti-Trypanosoma cruzi drug.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Pharmacological approaches to antitrypanosomal chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Combination chemotherapy of CNS trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Combination Therapy of Trypanosomiasis Using Diminazene and Non-Steroidal Anti-inflammatory Drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Trypanocidal resistance in Trypanosoma evansi in vitro: effects of verapamil, cyproheptidine, desipramine and chlorpromazine alone and in combination with trypanocides

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Allium sativum-induced death of African trypanosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Trypanocidal effects of curcumin in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Antiprotozoal activity of aporphine alkaloids isolated from Unonopsis buchtienii (Annonaceae).

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Trypanocidal effects of gallic acid and related compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

The glycosome of trypanosomes and Leishmania

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Trypanosoma brucei contains a 2,3-bisphosphoglycerate independent phosphoglycerate mutase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

N-n-alkyl-3,4-dihydroxybenzamides as inhibitors of the trypanosome alternative oxidase: activity in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Oral and intraperitoneal treatment of Trypanosoma brucei brucei with a combination of ascofuranone and glycerol in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

The Achilles' heel of trypanosomatids: trypanothione-mediated hydroperoxide metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Studies on lipidomimetic derivatives of alpha-difluoromethylornithine (DFMO) to enhance the bioavailability in a Trypanosoma B. brucei murine trypanosomiasis model

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

In vitro trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Cure of murine Trypanosoma brucei rhodesiense infections with an S-adenosylmethionine decarboxylase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine decarboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Irreversible inhibition of S-adenosylmethionine decarboxylase of Trypanosoma brucei brucei by S-adenosylmethionine analogues

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Synthesis and antitrypanosomal activities of a series of 7-deaza-5'-noraristeromycin derivatives with variations in the cyclopentyl ring substituents.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

5'-Alkyl-substituted analogs of 5'-methylthioadenosine as trypanocides

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Toxicity of myristic acid analogs toward African trypanosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Trypanocidal analogs of myristate and myristoyllysophosphatidylcholine

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Specialized fatty acid synthesis in African trypanosomes: myristate for GPI anchors

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Differences between the trypanosomal and human GlcNAc-PI de-N-acetylases of glycosylphosphatidylinositol membrane anchor biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Selective inhibitors of the glycosylphosphatidylinositol biosynthetic pathway of Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Inhibition of GPI phospholipase C from Trypanosoma brucei by fluoro-inositol dodecylphosphonates

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Topoisomerases in kinetoplastids

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Antitrypanosomal activity of camptothecin analogs. Structure-activity correlations

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Action of DNA-gyrase inhibiting derivatives of 4-oxo-1, 4-dihydro-3-pyridinecarboxylic acid against Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Treatment of late stage rhodesiense trypanosomiasis using suramin and eflornithine: report of six cases

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Suramin and metronidazole in the treatment of Trypanosoma brucei rhodesiense

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Metronidazole and suramin combination in the treatment of arsenical refractory Rhodesian sleeping sickness--a case study

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Relapses following treatment of early-stage Trypanosoma brucei gambiense sleeping sickness with a combination of pentamidine and suramin

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Gambian trypanosomiasis and synergism between melarsoprol and eflornithine: first case report

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Cationic antiprotozoal drugs. Trypanocidal activity of 2-(4'-formylphenyl)imidazo[1,2-a]pyridinium guanylhydrazones and related derivatives of quaternary heteroaromatic compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Methylating agents as trypanocides

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Enhancement of the trypanocidal activity of methyltriazenes in an animal model by the addition of an amidino group

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Synthesis and antitrypanosomal evaluation of some thiazole-containing amino acids and peptides

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

(S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine [(S)-HPMPA]: a purine analogue with trypanocidal activity in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

The effect of spiroarsoranes on Trypanosoma brucei brucei and T. b. rhodesiense

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Efficacy of anticancer alkylphosphocholines in Trypanosoma brucei subspecies

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Lysis of trypanosomes by peptidyl fluoromethyl ketones

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Cysteine proteinase inhibitors kill cultured bloodstream forms of Trypanosoma brucei brucei

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Trypanocidal effect of Ir-(COD)-pentamidine tetraphenylborate on Trypanosoma brucei and T. b. gambiense rodent models and serum kinetics in sheep.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Cytotoxicity of (2,2':6',2''-terpyridine)platinum(II) complexes to Leishmania donovani, Trypanosoma cruzi, and Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

The farnesyltransferase inhibitor manumycin A is a novel trypanocide with a complex mode of action including major effects on mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4922%2800%2901829-8

7 January 2021

10.1016/S1471-4922(00)01829-8

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11137740