(Q34119479)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

COX-2 and Alzheimer's disease: potential roles in inflammation and neurodegeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

O'Banion MK

series ordinal

1

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 October 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Investigational Drugs

3 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

1521-1536

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

3 November 2019

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Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells

21 January 2018

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Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes

21 January 2018

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Amyloid-beta peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release.

21 January 2018

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Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease

21 January 2018

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Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

21 January 2018

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Interleukin-1 stimulates the beta-amyloid precursor protein promoter

21 January 2018

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Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain

21 January 2018

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beta-Amyloid converts an acute phase injury response to chronic injury responses

21 January 2018

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Inflammation and Alzheimer's disease pathogenesis

21 January 2018

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Inflammatory processes and antiinflammatory drugs in Alzheimer's disease: a current appraisal

21 January 2018

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Rheumatoid arthritis and senile dementia of the Alzheimer's type.

21 January 2018

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Anti-inflammatory drugs and Alzheimer disease.

21 January 2018

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Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

21 January 2018

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Risk of Alzheimer's disease and duration of NSAID use.

21 January 2018

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Clinical trial of indomethacin in Alzheimer's disease.

21 January 2018

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Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.

21 January 2018

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Glucocorticoids in Alzheimer's disease. The story so far.

21 January 2018

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Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

21 January 2018

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Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase

21 January 2018

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Prostanoid receptors. Structure, function, and distribution

21 January 2018

1 reference

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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

The growing phospholipase A2 superfamily of signal transduction enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Prostaglandin synthase-1 and prostaglandin synthase-2 are coupled to distinct phospholipases for the generation of prostaglandin D2 in activated mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Cytosolic phospholipase A2 is required for cytokine-induced expression of type IIA secretory phospholipase A2 that mediates optimal cyclooxygenase-2-dependent delayed prostaglandin E2 generation in rat 3Y1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: possible role of cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

The induction of ICAM-1 in human cerebromicrovascular endothelial cells (HCEC) by ischemia-like conditions promotes enhanced neutrophil/HCEC adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2

21 January 2018

1 reference

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

21 January 2018

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Aspirin-like molecules that covalently inactivate cyclooxygenase-2.

21 January 2018

1 reference

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Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids

21 January 2018

1 reference

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Sustained induction of prostaglandin endoperoxide synthase-2 by seizures in hippocampus. Inhibition by a platelet-activating factor antagonist

21 January 2018

1 reference

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Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: implications for Alzheimer's disease.

21 January 2018

1 reference

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In vitro and in vivo localization of prostaglandin H synthase in fetal sheep neurons.

21 January 2018

1 reference

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Cyclooxygenases and the central nervous system

21 January 2018

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Cyclo-oxygenase-2 messenger RNA induction in focal cerebral ischemia.

21 January 2018

1 reference

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Cyclooxygenase-2 is induced globally in infarcted human brain

21 January 2018

1 reference

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TNF alpha and IL-1beta mediate intercellular adhesion molecule-1 induction via microglia-astrocyte interaction in CNS radiation injury.

21 January 2018

1 reference

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Prostaglandin G/H synthase-2 (cyclooxygenase-2) mRNA expression is decreased in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Expression of COX-2 by normal and reactive astrocytes in the adult rat central nervous system.

21 January 2018

1 reference

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A light and electron microscopic study of cytoplasmic phospholipase A2 and cyclooxygenase-2 in the hippocampus after kainate lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Cyclooxygenases-1 and -2 are differentially localized to microglia and endothelium in rat EAE and glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

The febrile response to lipopolysaccharide is blocked in cyclooxygenase-2(-/-), but not in cyclooxygenase-1(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Induction by lipopolysaccharide of cyclooxygenase-2 mRNA in rat brain; its possible role in the febrile response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of prostaglandin synthesis responsible for fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Expression of inducible cyclooxygenase mRNA in the mouse brain after systemic administration of bacterial lipopolysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

A selective inhibitor of cyclooxygenase-2 reverses endotoxin-induced pyretic responses in non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Expression and vascular effects of cyclooxygenase-2 in brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Role of inducible nitric oxide synthase and cyclooxygenase-2 in endotoxin-induced cerebral hyperemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Decreased prostaglandin synthesis in postmortem cerebral cortex from patients with Alzheimer's disease

21 January 2018

1 reference

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Cyclo-oxygenase-2 mediates P2Y receptor-induced reactive astrogliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Indomethacin reverses the microglial response to amyloid beta-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Peripheral administration of novel anti-inflammatories can attenuate the effects of chronic inflammation within the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

A cyclooxygenase-2 inhibitor attenuates white matter damage in chronic cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Interaction between inducible nitric oxide synthase and cyclooxygenase-2 after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Regulation of cyclooxygenase enzymes by nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Pharmacological analysis of cyclooxygenase-1 in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Activators of peroxisome proliferator-activated receptor-gamma (PPARgamma) inhibit inducible nitric oxide synthase expression but increase heme oxygenase-1 expression in rat glial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Brain tissue injury and blood-brain barrier opening induced by injection of LGE2 or PGE2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Cerebromicrovascular pathology in Alzheimer's disease compared to normal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

The early induction of cyclooxygenase 2 associated with neurofibrillary degeneration in brains of patients with Fukuyama-type congenital muscular dystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.8.10.1521

10.1517/13543784.8.10.1521

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11139808%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference