(Q34121447)

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Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk

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scholarly article

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk (English)

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Europe PubMed Central

31 July 2017

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author name string

Artemis P Simopoulos

1

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Europe PubMed Central

31 July 2017

publication date

1 July 2010

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Europe PubMed Central

31 July 2017

Experimental Biology and Medicine

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Europe PubMed Central

31 July 2017

235

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Europe PubMed Central

31 July 2017

7

1 reference

Europe PubMed Central

31 July 2017

785-795

1 reference

Europe PubMed Central

31 July 2017

The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases

1 reference

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Common purslane: a source of omega-3 fatty acids and antioxidants

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Alpha-linolenic acid metabolism in men and women: nutritional and biological implications.

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Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase

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Cloning, expression, and fatty acid regulation of the human delta-5 desaturase

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Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART).

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Cardiovascular effects of fish oils. Beyond the platelet

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Cardiovascular Effects of n-3 Fatty Acids

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Prophylaxis of atherosclerosis with marine omega-3 fatty acids. A comprehensive strategy

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Essential fatty acids in growth and development

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Fishing for prostanoids: deciphering the developmental functions of cyclooxygenase-derived prostaglandins

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The impact of eicosanoids on the crosstalk between innate and adaptive immunity: the key roles of dendritic cells

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Arachidonic acid as a retrograde signal controlling growth and dynamics of retinotectal arbors.

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Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers

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Role of cyclooxygenase-1 and -2, phospholipase C, and protein kinase C in prostaglandin-mediated gastroprotection

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Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

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Genetically determined variation in polyunsaturated fatty acid metabolism may result in different dietary requirements

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Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids

1 reference

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Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism

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Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk

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Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

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Poor metabolisers of debrisoquine reveal their true colours

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A genome-wide association study identifies novel risk loci for type 2 diabetes

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A common variant associated with prostate cancer in European and African populations

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A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

1 reference

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21 January 2018

Complement factor H polymorphism in age-related macular degeneration

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Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family

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A common allele on chromosome 9 associated with coronary heart disease

1 reference

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Three-year tracking of fatty acid composition of plasma phospholipids in healthy children

1 reference

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21 January 2018

cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family

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A genome-wide search for quantitative trait loci underlying asthma

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The role of essential fatty acids in development

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Infant cerebral cortex phospholipid fatty-acid composition and diet

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From genomics to chemical genomics: new developments in KEGG

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Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases

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Why g matters: The complexity of everyday life

1 reference

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The UCSC Genome Browser Database

1 reference

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Omega-3 fatty acids and rodent behavior

1 reference

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The genetics of g in human and mouse

1 reference

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21 January 2018

SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease

1 reference

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21 January 2018

Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study

1 reference

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21 January 2018

Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis

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Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling

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Expression of 5-lipoxygenase in human colorectal cancer

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Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.

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Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase

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Expression of 5-oxoETE receptor in prostate cancer cells: critical role in survival

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Inhibition of 5-lipoxygenase pathway suppresses the growth of bladder cancer cells

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5-lipoxygenase and 5-lipoxygenase-activating protein gene polymorphisms, dietary linoleic acid, and risk for breast cancer

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5' end of HMG CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription

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The role of fatty acids in gene expression: health implications

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Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.

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Relationship between fat cell size and number and fatty acid composition in adipose tissue from different fat depots in overweight/obese humans.

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Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects

1 reference

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Transcriptomics applied to obesity and caloric restriction.

1 reference

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FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases

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21 January 2018

Association of frequent consumption of fatty fish with prostate cancer risk is modified by COX-2 polymorphism

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21 January 2018

Identifiers

10.1258/EBM.2010.009298

1 reference

Europe PubMed Central

31 July 2017

1 reference

Europe PubMed Central

31 July 2017

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