(Q34125637)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20624445%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

review article

1 reference

title

TBX2 and TBX3: the special value for anticancer drug targets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20624445%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

5

1 reference

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7 February 2020

Ming-Liang He

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20624445%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Juan Lu

1

1 reference

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7 February 2020

Xiang-Ping Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20624445%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Qi Dong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20624445%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Hsiang-Fu Kung

4

1 reference

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7 February 2020

language of work or name

English

0 references

publication date

17 July 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20624445%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

number of pages

7

1 reference

Biochimica et Biophysica Acta

inferred from page(s)

published in

1 reference

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7 February 2020

volume

1806

1 reference

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7 February 2020

issue

2

1 reference

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7 February 2020

page(s)

268-274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20624445%20AND%20SRC:MED&resulttype=core&format=json

Tumor cell senescence in cancer treatment

7 February 2020

cites work

1 reference

12 December 2020

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

1 reference

12 December 2020

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs

1 reference

12 December 2020

Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome

1 reference

12 December 2020

Tbx3 represses E-cadherin expression and enhances melanoma invasiveness.

1 reference

12 December 2020

Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer.

1 reference

12 December 2020

Met proto-oncogene and insulin-like growth factor binding protein 3 overexpression correlates with metastatic ability in well-differentiated pancreatic endocrine neoplasms

1 reference

12 December 2020

Multiple genes at 17q23 undergo amplification and overexpression in breast cancer

1 reference

12 December 2020

The T protein encoded by Brachyury is a tissue-specific transcription factor

1 reference

12 December 2020

Wnt/beta-catenin signaling in development and disease

1 reference

12 December 2020

Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome

1 reference

12 December 2020

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1 reference

12 December 2020

UV-mediated regulation of the anti-senescence factor Tbx2.

1 reference

12 December 2020

Rb binds c-Jun and activates transcription

1 reference

12 December 2020

Ectopic Tbx2 expression results in polyploidy and cisplatin resistance

1 reference

12 December 2020

A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome

1 reference

12 December 2020

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

12 December 2020

Transcriptional modification by a CASK-interacting nucleosome assembly protein

1 reference

12 December 2020

Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6

1 reference

12 December 2020

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

1 reference

12 December 2020

TBX3 and its splice variant TBX3 + exon 2a are functionally similar.

1 reference

12 December 2020

Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1.

1 reference

12 December 2020

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

1 reference

12 December 2020

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

1 reference

12 December 2020

Cloning of the T gene required in mesoderm formation in the mouse

1 reference

12 December 2020

A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins

1 reference

12 December 2020

Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

1 reference

12 December 2020

TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines

1 reference

12 December 2020

The retinoblastoma protein modulates Tbx2 functional specificity

1 reference

12 December 2020

Synthetic peptides outside the spike protein heptad repeat regions as potent inhibitors of SARS-associated coronavirus

1 reference

12 December 2020

Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule

1 reference

12 December 2020

Histone deacetylase inhibitors in cancer therapy

1 reference

12 December 2020

The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.

1 reference

12 December 2020

Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation

1 reference

12 December 2020

Genes differentially expressed in human lung fibroblast cells transformed by glycidyl methacrylate.

1 reference

12 December 2020

TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice

1 reference

12 December 2020

Evolution of mouse T-box genes by tandem duplication and cluster dispersion.

1 reference

12 December 2020

Cellular senescence as a tumor-suppressor mechanism

1 reference

12 December 2020

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

12 December 2020

The T-box gene family

1 reference

12 December 2020

TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases

1 reference

12 December 2020

TBX2 is preferentially amplified in BRCA1- and BRCA2-related breast tumors

1 reference

12 December 2020

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

1 reference

12 December 2020

ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers

1 reference

12 December 2020

The regulation of E2F by pRB-family proteins

1 reference

12 December 2020

Anchorage-independent growth of pocket protein-deficient murine fibroblasts requires bypass of G2 arrest and can be accomplished by expression of TBX2.

1 reference

12 December 2020

The retinoblastoma protein and cell cycle control

1 reference

12 December 2020

Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal

1 reference

12 December 2020

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence

1 reference

12 December 2020

Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome

1 reference

12 December 2020

Wnt signalling mediated by Tbx2b regulates cell migration during formation of the neural plate.

1 reference

12 December 2020

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

1 reference

12 December 2020

A role for Tbx2 in the regulation of the alpha2(1) collagen gene in human fibroblasts

1 reference

12 December 2020

Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain

1 reference

12 December 2020

Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer

1 reference

12 December 2020

Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer

1 reference

12 December 2020

Expression and clinical significance of tbx2 in pancreatic cancer

1 reference

12 December 2020

T-box genes in early embryogenesis

1 reference

12 December 2020

Structural analysis of the 17q22-23 amplicon identifies several independent targets of amplification in breast cancer cell lines and tumors

1 reference

12 December 2020

p21WAF1-derived peptides linked to an internalization peptide inhibit human cancer cell growth

1 reference

12 December 2020

Identification, characterization, and localization to chromosome 17q21-22 of the human TBX2 homolog, member of a conserved developmental gene family

1 reference

12 December 2020

p14(ARF) regulates E2F activity

1 reference

12 December 2020

T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells

1 reference

12 December 2020

Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients

1 reference

12 December 2020

p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor

1 reference

12 December 2020

T-box genes: what they do and how they do it.

1 reference

12 December 2020

E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

1 reference

12 December 2020

The T-box transcription factor Tbx2: its role in development and possible implication in cancer

1 reference

12 December 2020

Determinants of T box protein specificity.

1 reference

12 December 2020

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

1 reference

12 December 2020

1 reference

12 December 2020

Wnt signalling in stem cells and cancer

1 reference

12 December 2020

A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding

1 reference

12 December 2020

Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome

1 reference

12 December 2020

E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer

1 reference

12 December 2020

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

12 December 2020

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator

1 reference

12 December 2020

1 reference

12 December 2020

Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor

1 reference

12 December 2020

Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor

1 reference

12 December 2020