(Q34126654)

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Computational model of the complex between GR113808 and the 5-HT4 receptor guided by site-directed mutagenesis and the crystal structure of rhodopsin

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Computational model of the complex between GR113808 and the 5-HT4 receptor guided by site-directed mutagenesis and the crystal structure of rhodopsin (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

crystal structure

1 reference

based on heuristic

inferred from title

computational model

1 reference

based on heuristic

inferred from title

Mercedes Campillo

1 reference

ORCID Public Data File 2021

author name string

López-Rodríguez ML

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Murcia M

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Benhamú B

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Olivella M

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Campillo M

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Pardo L

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

publication date

1 November 2001

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Journal of Computer - Aided Molecular Design

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1025-1033

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

describes a project that uses

site-directed mutagenesis

1 reference

based on heuristic

inferred from title

Identification of two serine residues involved in agonist activation of the beta-adrenergic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bayesian statistical analysis of protein side-chain rotamer preferences

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 5-HT4 receptor antagonist ML10375 inhibits the constitutive activity of human 5-HT4(c) receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aromatic-aromatic interaction: a mechanism of protein structure stabilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrahelical hydrogen bonding of serine, threonine and cysteine residues within alpha-helices and its relevance to membrane-bound proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central 5-HT4 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a radioligand binding assay for 5-HT4 receptors in guinea-pig and rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GPCRDB: an information system for G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phe310 in transmembrane VI of the alpha1B-adrenergic receptor is a key switch residue involved in activation and catecholamine ring aromatic bonding

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of conserved aromatic residues essential for agonist binding and second messenger production at 5-hydroxytryptamine2A receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and structure-activity relationships of a new model of arylpiperazines. Study of the 5-HT(1a)/alpha(1)-adrenergic receptor affinity by classical hansch analysis, artificial neural networks, and computational simulation of ligand recognitio

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arrangement of rhodopsin transmembrane α-helices

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G protein-coupled receptors. I. Diversity of receptor-ligand interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine and threonine residues bend alpha-helices in the chi(1) = g(-) conformation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzene Forms Hydrogen Bonds with Water

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics for a salt-bridge switch mutation of the alpha(1b) adrenergic receptor. Altered pharmacology and rescue of constitutive activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raster3D: photorealistic molecular graphics

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen bonds with pi-acceptors in proteins: frequencies and role in stabilizing local 3D structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative receptor mapping of serotoninergic 5-HT3 and 5-HT4 binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploration of the ligand binding site of the human 5-HT(4) receptor by site-directed mutagenesis and molecular modeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Architecture of G Protein-Coupled Receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential ergoline and ergopeptine binding to 5-hydroxytryptamine2A receptors: ergolines require an aromatic residue at position 340 for high affinity binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single point mutation (Phe340-->Leu340) of a conserved phenylalanine abolishes 4-[125I]iodo-(2,5-dimethoxy)phenylisopropylamine and [3H]mesulergine but not [3H]ketanserin binding to 5-hydroxytryptamine2 receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11989623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1014895611874

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

DBLP publication ID

journals/jcamd/Lopez-RodriguezMBOCP01

1 reference

DBLP Dataset 2021-01-02

28 January 2021

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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