(Q34129215)

31 July 2017

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title

Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions (English)

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31 July 2017

Ritter JK

1

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31 July 2017

publication date

1 December 2000

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Chemico-biological Interactions

31 July 2017

published in

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31 July 2017

volume

129

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31 July 2017

issue

1-2

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31 July 2017

page(s)

171-193

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Properties of acyl glucuronides: implications for studies of the pharmacokinetics and metabolism of acidic drugs

31 July 2017

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Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon

7 January 2021

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Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes

7 January 2021

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Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: a novel role for phase-II-mediated bioactivation in the hepatocarcinogenicity of the parent aglycones?

7 January 2021

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Studies on the reactivity of acyl glucuronides--VI. Modulation of reversible and covalent interaction of diflunisal acyl glucuronide and its isomers with human plasma protein in vitro

7 January 2021

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Identification and analysis of drug-responsive expression of UDP-glucuronosyltransferase family 1 (UGT1) isozyme in rat hepatic microsomes using anti-peptide antibodies

7 January 2021

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Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation

7 January 2021

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Stereoselective glucuronidation of (R)- and (S)-naproxen by recombinant rat phenol UDP-glucuronosyltransferase (UGT1A1) and its human orthologue

7 January 2021

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Hepatic microsomal glucuronidation of clofibric acid in the adult and neonate albino rat

7 January 2021

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Analgesic activity of morphine-6-glucuronide

7 January 2021

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Morphine and metabolite behavior after different routes of morphine administration: demonstration of the importance of the active metabolite morphine-6-glucuronide

7 January 2021

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Chronic morphine therapy for cancer pain: plasma and cerebrospinal fluid morphine and morphine-6-glucuronide concentrations

7 January 2021

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In vitro evidence for the involvement of at least two forms of human liver UDP-glucuronosyltransferase in morphine 3-glucuronidation

7 January 2021

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The enantioselective glucuronidation of morphine in rats and humans. Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme

7 January 2021

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Purification of a phenobarbital-inducible morphine UDP-glucuronyltransferase isoform, absent from Gunn rat liver

7 January 2021

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Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols

7 January 2021

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Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Formation of beta-glucuronides and of beta-galacturonides of various retinoids catalyzed by induced and noninduced microsomal UDP-glucuronosyltransferases of rat liver

7 January 2021

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Identification of a rat oltipraz-inducible UDP-glucuronosyltransferase (UGT1A7) with activity towards benzo(a)pyrene-7,8-dihydrodiol

7 January 2021

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4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7

7 January 2021

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7 January 2021

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7 January 2021

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Characterization of UDP-glucuronosyltransferases active on steroid hormones

7 January 2021

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Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7

7 January 2021

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Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms

7 January 2021

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Alteration of human UDP-glucuronosyltransferase UGT2B17 regio-specificity by a single amino acid substitution

7 January 2021

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cDNA cloning and characterization of the human UDP glucuronosyltransferase, UGT1A3

7 January 2021

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Expression and inducibility of the human bilirubin UDP-glucuronosyltransferase UGT1A1 in liver and cultured primary hepatocytes: evidence for both genetic and environmental influences

7 January 2021

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The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome

7 January 2021

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Genetic defect of bilirubin UDP-glucuronosyltransferase in the hyperbilirubinemic Gunn rat

7 January 2021

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Tissue-specific constitutive and inducible expression of rat phenol UDP-glucuronosyltransferase

7 January 2021

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Paracetamol glucuronidation by recombinant rat and human phenol UDP-glucuronosyltransferases

7 January 2021

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Induction of a rat liver benzo[a]pyrene-trans-7,8-dihydrodiol glucuronidating activity by oltipraz and beta-naphthoflavone

7 January 2021

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UDP-glucuronosyltransferase UGT1A7 induced in rat small intestinal mucosa by oral administration of 2-naphthoflavone.

7 January 2021

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Transcriptional activation of the UDP-glucuronosyltransferase 1A7 gene in rat liver by aryl hydrocarbon receptor ligands and oltipraz.

7 January 2021

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Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8

7 January 2021

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UDP-glucuronosyltransferase activity in human liver and colon

7 January 2021

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Gilbert's syndrome is caused by a heterozygous missense mutation in the gene for bilirubin UDP-glucuronosyltransferase

7 January 2021

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The expression of UDP-glucuronosyltransferases of the UGT1 family in human liver and kidney and in response to drugs

7 January 2021

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Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications

7 January 2021

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Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus

7 January 2021

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Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8.

7 January 2021

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The monkey and human uridine diphosphate-glucuronosyltransferase UGT1A9, expressed in steroid target tissues, are estrogen-conjugating enzymes

7 January 2021

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Two human liver cDNAs encode UDP-glucuronosyltransferases with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives

7 January 2021

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UDP-glucuronosyltransferases in human intestinal mucosa

7 January 2021

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Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene

7 January 2021

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Glucuronide conjugates of 4-aminobiphenyl and its N-hydroxy metabolites. pH stability and synthesis by human and dog liver

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0009-2797(00)00198-8

1 reference

31 July 2017

1 reference