Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34141552)
Watch
English
The endoplasmic reticulum: integration of protein folding, quality control, signaling and degradation.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
The endoplasmic reticulum: integration of protein folding, quality control, signaling and degradation
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
main subject
endoplasmic reticulum
0 references
protein folding
0 references
quality control
0 references
author
David Y. Thomas
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author name string
E Chevet
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
P H Cameron
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
M F Pelletier
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
J J Bergeron
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
publication date
1 February 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
published in
Current Opinion in Structural Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
volume
11
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
page(s)
120-124
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
cites work
Expression of a gene for cyclophilin which contains an amino-terminal endoplasmic reticulum-targeting signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein folding in a specialized compartment: the endoplasmic reticulum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role and regulation of the ER chaperone BiP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calnexin family members as modulators of genetic diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein disulfide isomerase: the multifunctional redox chaperone of the endoplasmic reticulum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycoprotein folding in the endoplasmic reticulum: a tale of three chaperones?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of N-oligosaccharide endoplasmic reticulum processing reactions in glycoprotein folding and degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and folding of nascent polypeptide chains during protein translocation in the endoplasmic reticulum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unfolded protein response-induced BiP/Kar2p production protects cell growth against accumulation of misfolded protein aggregates in the yeast endoplasmic reticulum.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chaperone selection during glycoprotein translocation into the endoplasmic reticulum.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Setting the standards: quality control in the secretory pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular basis for the recognition of misfolded glycoproteins by the UDP-Glc:glycoprotein glucosyltransferase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Processing by endoplasmic reticulum mannosidases partitions a secretion-impaired glycoprotein into distinct disposal pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oligosaccharide modification in the early secretory pathway directs the selection of a misfolded glycoprotein for degradation by the proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perk is essential for translational regulation and cell survival during the unfolded protein response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of NF-kappa B by ER stress requires both Ca2+ and reactive oxygen intermediates as messengers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endoplasmic reticulum degradation. Reverse protein transport and its end in the proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retrograde protein translocation: ERADication of secretory proteins in health and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Cue1p in ubiquitination and degradation at the ER surface
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation by CK2 and MAPK enhances calnexin association with ribosomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Promotion of transferrin folding by cyclic interactions with calnexin and calreticulin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucosidase and mannosidase inhibitors mediate increased secretion of mutant alpha1 antitrypsin Z.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oligosaccharide trimming plays a role in the endoplasmic reticulum-associated degradation of tyrosinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A regulatory link between ER-associated protein degradation and the unfolded-protein response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2800%2900168-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-440X(00)00168-8
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
PubMed ID
11179901
1 reference
stated in
Europe PubMed Central
PubMed ID
11179901
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11179901%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit