(Q34150626)

31 July 2017

title

Aging impairs myocardial fatty acid and ketone oxidation and modifies cardiac functional and metabolic responses to insulin in mice (English)

1 reference

31 July 2017

0 references

1 reference

Outi M Hyyti

1

1 reference

31 July 2017

Dolena Ledee

2

1 reference

31 July 2017

Xue-Han Ning

3

1 reference

31 July 2017

Ming Ge

4

1 reference

31 July 2017

Michael A Portman

5

1 reference

31 July 2017

publication date

2 July 2010

1 reference

American Journal of Physiology Heart and Circulatory Physiology

31 July 2017

published in

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31 July 2017

volume

299

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31 July 2017

issue

3

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31 July 2017

page(s)

H868-75

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Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha)

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Superior cardiac function via anaplerotic pyruvate in the immature swine heart after cardiopulmonary bypass and reperfusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Cardioselective dominant-negative thyroid hormone receptor (Delta337T) modulates myocardial metabolism and contractile efficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Morphometric changes induced by amino acid supplementation in skeletal and cardiac muscles of old mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Response of isolated guinea pig myocardium to insulin therapy during normothermia and graded hypothermia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Fatty acid oxidation by isolated perfused working hearts of aged rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944494

Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle

5 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Influence of substrate supply on cardiac efficiency, as measured by pressure-volume analysis in ex vivo mouse hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Thyroid hormone controls myocardial substrate metabolism through nuclear receptor-mediated and rapid posttranscriptional mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Exercise training improves cardiac function-related gene levels through thyroid hormone receptor signaling in aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Impact of aging on substrate metabolism by the human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Profiling substrate fluxes in the isolated working mouse heart using 13C-labeled substrates: focusing on the origin and fate of pyruvate and citrate carbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

CD36 expression contributes to age-induced cardiomyopathy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Triidothyronine and epinephrine rapidly modify myocardial substrate selection: a (13)C isotopomer analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Effects of chronic activation of peroxisome proliferator-activated receptor-alpha or high-fat feeding in a rat infarct model of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Metabolic remodeling in the aging heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Influence of perfusate calcium concentration on the inotropic insulin effect in isolated guinea pig and rat hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00931.2009

Mitochondrial metabolism and substrate competition in the aging Fischer rat heart

21 January 2018

1 reference

12 December 2020

Contribution of various substrates to total citric acid cycle flux and anaplerosis as determined by 13C isotopomer analysis and O2 consumption in the heart

1 reference

12 December 2020

The dominant negative thyroid hormone receptor beta-mutant {Delta}337T alters PPAR{alpha} signaling in heart

1 reference

12 December 2020

Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts

1 reference

12 December 2020

Long-Term Effects of Increased Glucose Entry on Mouse Hearts During Normal Aging and Ischemic Stress

1 reference

12 December 2020

Assessment of cardiac function with the pressure-volume conductance system following myocardial infarction in mice

1 reference

12 December 2020

Aging is associated with myocardial insulin resistance and mitochondrial dysfunction

1 reference

12 December 2020

Peroxisome proliferator-activated receptor alpha down-regulation is associated with enhanced ceramide levels in age-associated cardiac hypertrophy

1 reference

12 December 2020

10.1152/AJPHEART.00931.2009

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference