(Q34150775)

31 July 2017

Principles of early drug discovery (English)

1 reference

31 July 2017

1 reference

J P Hughes

1

1 reference

31 July 2017

S Rees

series ordinal

2

1 reference

31 July 2017

S B Kalindjian

series ordinal

3

1 reference

31 July 2017

K L Philpott

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 March 2011

1 reference

British Journal of Pharmacology

31 July 2017

1 reference

31 July 2017

162

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31 July 2017

1239-1249

1 reference

31 July 2017

6

1 reference

Knocking down barriers: advances in siRNA delivery

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

The promises and pitfalls of RNA-interference-based therapeutics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Target discovery from data mining approaches

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Comprehensive screening for antigens overexpressed on carcinomas via isolation of human mAbs that may be therapeutic

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Virtual screening strategies in drug discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Probes for chemical genomics by design

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Recombinant aequorin as reporter of changes in intracellular calcium in mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Cell-based assays: fuelling drug discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

HTS and hit finding in academia--from chemical genomics to drug discovery

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

The multiple roles of computational chemistry in fragment-based drug design

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Knowledge based identification of MAO-B selective inhibitors using pharmacophore and structure based virtual screening models.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

An SCN9A channelopathy causes congenital inability to experience pain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

High-throughput screening: update on practices and success

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Cell-based versus isolated target screening: how lucky do you feel?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058157

Use of primary human cells in high-throughput screens

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21091654

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2010.01127.X

1 reference

31 July 2017

1 reference

31 July 2017

1 reference