(Q34152068)

31 July 2017

title

Defining the genetic origins of three rheumatoid synovium-derived IgG rheumatoid factors (English)

1 reference

31 July 2017

M Deftos

1

1 reference

31 July 2017

T Olee

series ordinal

2

1 reference

31 July 2017

D A Carson

series ordinal

3

1 reference

31 July 2017

P P Chen

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 June 1994

1 reference

Journal of Clinical Investigation

31 July 2017

published in

1 reference

31 July 2017

volume

93

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31 July 2017

issue

6

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31 July 2017

page(s)

2545-2553

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Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus

31 July 2017

cites work

1 reference

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5 July 2018

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Fourteen nucleotides in the second complementarity-determining region of a human heavy-chain variable region gene are identical with a sequence in a human D minigene

5 July 2018

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5 July 2018

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Most kappa immunoglobulin mRNA in human lymphocytes is homologous to a small family of germ-line V genes

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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A novel family of variable region genes of the human immunoglobulin heavy chain

5 July 2018

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A hyperconversion mechanism generates the chicken light chain preimmune repertoire.

5 July 2018

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A highly informative probe for two polymorphic Vh gene regions that contain one or more autoantibody-associated Vh genes

5 July 2018

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The smaller human VH gene families display remarkably little polymorphism

5 July 2018

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A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation

5 July 2018

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5 July 2018

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Serologic and molecular characterization of a human monoclonal rheumatoid factor derived from rheumatoid synovial cells.

5 July 2018

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Structural analyses of human developmentally regulated Vh3 genes.

5 July 2018

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Rheumatoid arthritis. Pathophysiology and implications for therapy

5 July 2018

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The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidenc

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Autoantibodies and the fetal antibody repertoire

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Possible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Structure and expression of the human immunoglobulin lambda genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Nucleotide sequences and three-dimensional modelling of the VH and VL domains of two human monoclonal antibodies specific for the D antigen of the human Rh-blood-group system

5 July 2018

1 reference

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Rheumatoid factors isolated from patients with autoimmune disorders are derived from germline genes distinct from those encoding the Wa, Po, and Bla cross-reactive idiotypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

A novel class of anti-DNA antibodies identified in BALB/c mice

5 July 2018

1 reference

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A segment of human Vh gene locus is duplicated

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

The rheumatoid factor reactivity of a human IgG monoclonal autoantibody is encoded by a variant V kappa II L chain gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven response

5 July 2018

1 reference

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The human cord blood antibody repertoire. Frequent usage of the VH7 gene family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Complete sequence of the genes encoding the VH and VL regions of low- and high- affinity monoclonal lgM and lgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Molecular basis of an autoantibody-associated restriction fragment length polymorphism that confers susceptibility to autoimmune diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

The human immunoglobulin kappa locus. Characterization of the duplicated A regions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Structure and specificities of anti-ganglioside autoantibodies associated with motor neuropathies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Molecular characterization of the human immunoglobulin V lambda I germline gene repertoire

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Cloning and reexpression of a functional human IgM anti-lipid A antibody

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Molecular analysis of human immunoglobulin V lambda germline genes: subgroups V lambda III and V lambda IV.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Human combinatorial antibody libraries to hepatitis B surface antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

A systematic approach to defining the germline gene counterparts of a mutated autoantibody from a patient with rheumatoid arthritis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Immunoglobulin heavy and light chain gene sequences of a human CD5 positive immunocytoma and sequences of four novel VHIII germline genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Synovial IgG rheumatoid factors show evidence of an antigen-driven immune response and a shift in the V gene repertoire compared to IgM rheumatoid factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

An anti-lipid A antibody obtained from the human fetal repertoire is encoded by VH6-V lambda 1 genes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Utilization of a potentially universal downstream primer in the rapid identification and characterization of V lambda genes from two new human V lambda gene families.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Generation and molecular analyses of two rheumatoid synovial fluid-derived IgG rheumatoid factors.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Molecular analysis of rheumatoid factors derived from rheumatoid synovium suggests an antigen-driven response in inflamed joints

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Human immunoglobulin D segments encoded in tandem multigenic families

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294479

Templated insertions in the rearranged chicken IgL V gene segment arise by intrachromosomal gene conversion

28 October 2018

1 reference

12 December 2020

Restricted diversity of the variable region nucleotide sequences of the heavy and light chains of a human rheumatoid factor

1 reference

12 December 2020

Polymorphisms and haplotypes in the human immunoglobulinx locus

1 reference

12 December 2020

A human anti-cardiolipin autoantibody is encoded by developementally restricted heavy and light chain variable region genes

1 reference

12 December 2020

Generation and Characterization of two Monoclonal Self-Associating IgG Rheumatoid Factors from a Rheumatoid Synovium

1 reference

12 December 2020

The immunoglobulin kappa locus: polymorphism and haplotypes of Caucasoid and non-Caucasoid individuals

1 reference

12 December 2020

Organization and evolution of variable region genes of the human immunoglobulin heavy chain

1 reference

12 December 2020

The role of clonal selection and somatic mutation in autoimmunity

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI117265

1 reference

31 July 2017

1 reference

31 July 2017

1 reference