(Q34153283)

31 July 2017

APCAP--activated protein C in acute pancreatitis: a double-blind randomized human pilot trial (English)

1 reference

31 July 2017

1 reference

Ville Pettilä

1

1 reference

31 July 2017

Lea Kyhälä

2

1 reference

31 July 2017

Marja-Leena Kylänpää

3

1 reference

31 July 2017

Ari Leppäniemi

4

1 reference

31 July 2017

Minna Tallgren

5

1 reference

31 July 2017

Antti Markkola

6

1 reference

31 July 2017

Pauli Puolakkainen

7

1 reference

31 July 2017

Heikki Repo

8

1 reference

31 July 2017

Esko Kemppainen

9

1 reference

31 July 2017

27 July 2010

1 reference

31 July 2017

1 reference

31 July 2017

14

1 reference

31 July 2017

4

1 reference

31 July 2017

R139

1 reference

https://scigraph.springernature.com/pub.10.1186/cc9203

31 July 2017

0 references

cites work

Scoring systems in acute pancreatitis: which one to use in intensive care units?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Protective mechanisms of activated protein C in severe inflammatory disorders.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Safety of drotrecogin alfa (activated) in severe sepsis: data from adult clinical trials and observational studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Better conduct of clinical trials: the control group in critical care trials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Evaluation of SOFA-based models for predicting mortality in the ICU: A systematic review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Use of activated protein C has no avail in the early phase of acute pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Decreased inflammation and improved survival with recombinant human activated protein C treatment in experimental acute pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Upregulated but insufficient generation of activated protein C is associated with development of multiorgan failure in severe acute pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Drotrecogin alfa (recombinant human activated protein C) in severe acute pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Acute pancreatitis: a possible role for activated protein C?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

The effect of activated protein C on experimental acute necrotizing pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Management of the critically ill patient with severe acute pancreatitis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

New serum markers for the detection of severe acute pancreatitis in humans.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Efficacy and safety of recombinant human activated protein C for severe sepsis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

A clinically based classification system for acute pancreatitis. Summary of the International Symposium on Acute Pancreatitis, Atlanta, Ga, September 11 through 13, 1992.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? Evidence-Based Medicine Working Group

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Factors influencing morbidity and mortality in acute pancreatitis; an analysis of 279 cases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Activated protein C improves the severity of severe acute pancreatitis via up-regulating the expressions of endothelial cell protein C receptor and thrombomodulin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Activated protein C improves lipopolysaccharide-induced cardiovascular dysfunction by decreasing tissular inflammation and oxidative stress

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Increasing evidence that the risks of rhAPC may outweigh its benefits.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Activated protein C: do more survive?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

A modified CT severity index for evaluating acute pancreatitis: improved correlation with patient outcome.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

The use of drotrecogin alfa (activated) in severe sepsis during acute pancreatitis - two case studies.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Statistical evaluation of ventilator-free days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945119

Activated protein C, an anticoagulant polypeptide, ameliorates severe acute pancreatitis via regulation of mitogen-activated protein kinases

28 October 2018

1 reference

12 December 2020

Disorders of hemostasis during the surgical management of severe necrotizing pancreatitis

1 reference

12 December 2020

"All in" for a huge pot: the PROWESS-SHOCK trial for refractory septic shock

1 reference

12 December 2020

Protein C activation during the initial phase of experimental acute pancreatitis in the rabbit

1 reference

12 December 2020

Multiple organ dysfunction associated with severe acute pancreatitis

1 reference

12 December 2020

Comparison of multiple organ dysfunction scores in the prediction of hospital mortality in the critically ill

1 reference

12 December 2020

CONSORT and QUOROM guidelines for reporting randomized clinical trials and systematic reviews

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC9203

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference