(Q34166879)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21351297%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Formation of the iron-oxo hydroxylating species in the catalytic cycle of aromatic amino acid hydroxylases (English)

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23 January 2020

2

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23 January 2020

Vidar R Jensen

series ordinal

4

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23 January 2020

author name string

Elaine Olsson

series ordinal

1

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23 January 2020

Knut Teigen

series ordinal

3

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23 January 2020

language of work or name

English

0 references

publication date

24 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21351297%20AND%20SRC:MED&resulttype=core&format=json

Chemistry—A European Journal

23 January 2020

published in

1 reference

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23 January 2020

volume

17

1 reference

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23 January 2020

issue

13

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23 January 2020

page(s)

3746-3758

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Mechanism of aromatic amino acid hydroxylation

23 January 2020

cites work

1 reference

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Selectivity and affinity determinants for ligand binding to the aromatic amino acid hydroxylases

21 January 2018

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A unique central tryptophan hydroxylase isoform

21 January 2018

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Tetrahydrobiopterin biosynthesis, regeneration and functions

21 January 2018

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Phenylalanine hydroxylase: absolute configuration and source of oxygen of the 4a-hydroxytetrahydropterin species

21 January 2018

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Non-heme iron enzymes: contrasts to heme catalysis

21 January 2018

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Single turnover kinetics of tryptophan hydroxylase: evidence for a new intermediate in the reaction of the aromatic amino acid hydroxylases

21 January 2018

1 reference

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Dioxygen activation at mononuclear nonheme iron active sites: enzymes, models, and intermediates

21 January 2018

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Direct spectroscopic evidence for a high-spin Fe(IV) intermediate in tyrosine hydroxylase

21 January 2018

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Direct detection of oxygen intermediates in the non-heme Fe enzyme taurine/alpha-ketoglutarate dioxygenase.

21 January 2018

1 reference

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The first direct characterization of a high-valent iron intermediate in the reaction of an alpha-ketoglutarate-dependent dioxygenase: a high-spin FeIV complex in taurine/alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli

21 January 2018

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Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase

21 January 2018

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EXAFS spectroscopic evidence for an Fe=O unit in the Fe(IV) intermediate observed during oxygen activation by taurine:alpha-ketoglutarate dioxygenase

21 January 2018

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Heme-Containing Oxygenases

21 January 2018

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High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin

21 January 2018

1 reference

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Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin

21 January 2018

1 reference

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Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 A resolution: self-hydroxylation of Phe300 and the pterin-binding site

21 January 2018

1 reference

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Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation

21 January 2018

1 reference

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2.0A resolution crystal structures of the ternary complexes of human phenylalanine hydroxylase catalytic domain with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine or L-norleucine...

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002910

Crystal structure of tryptophan hydroxylase with bound amino acid substrate

21 January 2018

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Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions.

21 January 2018

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Identification of a functional water channel in cytochrome P450 enzymes.

21 January 2018

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Self-hydroxylation of taurine/alpha-ketoglutarate dioxygenase: evidence for more than one oxygen activation mechanism

21 January 2018

1 reference

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Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase

21 January 2018

1 reference

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Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002910

Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002910

The structural basis of the recognition of phenylalanine and pterin cofactors by phenylalanine hydroxylase: implications for the catalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002910

Mechanism of aromatic hydroxylation by an activated FeIV=O core in tetrahydrobiopterin-dependent hydroxylases

21 January 2018

1 reference

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Mechanism of dioxygen cleavage in tetrahydrobiopterin-dependent amino acid hydroxylases

21 January 2018

1 reference

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Recent developments of the quantum chemical cluster approach for modeling enzyme reactions

21 January 2018

1 reference

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Reversible dioxygen binding to hemerythrin

21 January 2018

1 reference

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Natural population analysis

21 January 2018

1 reference

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Crystal structure of the dioxygen-bound heme oxygenase from Corynebacterium diphtheriae: implications for heme oxygenase function

21 January 2018

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Metal-histidine-glutamate as a regulator of enzymatic cycles: a case study of carbonic anhydrase.

21 January 2018

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Factors governing the protonation state of Zn-bound histidine in proteins: a DFT/CDM study

21 January 2018

1 reference

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Formation of a protonated trihydrobiopterin radical cation in the first reaction cycle of neuronal and endothelial nitric oxide synthase detected by electron paramagnetic resonance spectroscopy.

21 January 2018

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Life as aerobes: are there simple rules for activation of dioxygen by enzymes?

21 January 2018

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Reaction mechanisms of mononuclear non-heme iron oxygenases

21 January 2018

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Spectroscopy and kinetics of wild-type and mutant tyrosine hydroxylase: mechanistic insight into O2 activation

21 January 2018

1 reference

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Measurement of intrinsic rate constants in the tyrosine hydroxylase reaction

21 January 2018

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Density-functional thermochemistry. III. The role of exact exchange

21 January 2018

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van der Waals Volumes and Radii

21 January 2018

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Semiempirical GGA-type density functional constructed with a long-range dispersion correction.

21 January 2018

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Density functional theory with dispersion corrections for supramolecular structures, aggregates, and complexes of (bio)organic molecules

21 January 2018

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Double-hybrid density functionals with long-range dispersion corrections: higher accuracy and extended applicability

21 January 2018

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Theoretical thermodynamics for large molecules: walking the thin line between accuracy and computational cost.

21 January 2018

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Pterin-Dependent Amino Acid Hydroxylases

21 January 2018

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Formation of a Pterin Radical in the Reaction of the Heme Domain of Inducible Nitric Oxide Synthase with Oxygen†

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1002/CHEM.201002910

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21351297%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference