(Q34181688)

31 July 2017

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title

Physiological anticoagulation. Resistance to activated protein C and venous thromboembolism (English)

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31 July 2017

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venous thromboembolism

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1 reference

Dahlbäck B

1

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31 July 2017

language of work or name

English

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publication date

1 September 1994

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Journal of Clinical Investigation

31 July 2017

published in

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31 July 2017

volume

94

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31 July 2017

issue

3

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31 July 2017

page(s)

923-927

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Inherited predisposition to thrombosis

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Resistance to activated protein C as a basis for venous thrombosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Mutation in blood coagulation factor V associated with resistance to activated protein C.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Protein S binds to and inhibits factor Xa

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Increased risk of venous thrombosis in carriers of hereditary protein C deficiency defect

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Effects of thrombomodulin and coagulation Factor Va-light chain on protein C activation in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

The binding of activated protein C to factors V and Va

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Absence of thrombosis in subjects with heterozygous protein C deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Bovine coagulation factor V visualized with electron microscopy. Ultrastructure of the isolated activated forms and of the activation fragments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Identification of a new protein involved in the regulation of the anticoagulant activity of activated protein C. Protein S-binding protein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

The clinical spectrum of heterozygous protein C deficiency in a large New England kindred

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Identification of the binding site for activated protein C on the light chain of factors V and VIII.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

The coagulation cascade: initiation, maintenance, and regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Protein S and C4b-binding protein: components involved in the regulation of the protein C anticoagulant system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Incidence and clinical characteristics of hereditary disorders associated with venous thrombosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

The protein C anticoagulant pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

A novel exosite in the light chain of human activated protein C essential for interaction with blood coagulation factor Va.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295127

Inactivation of human coagulation factor V by activated protein C

28 October 2018

1 reference

12 December 2020

The effect of phospholipids, calcium ions and protein S on rate constants of human factor Va inactivation by activated human protein C

1 reference

12 December 2020

Thromboembolic disease--critical evaluation of laboratory investigation

1 reference

12 December 2020

Proteolysis of factor Va by factor Xa and activated protein C

1 reference

12 December 2020

Deficiencies of coagulation-inhibiting and fibrinolytic proteins in outpatients with deep-vein thrombosis

1 reference

12 December 2020

Anticoagulant protein C pathway defective in majority of thrombophilic patients

1 reference

12 December 2020

Arterial and venous thromboembolism with fatal outcome and resistance to activated protein C

1 reference

12 December 2020

Resistance to activated protein C in nine thrombophilic families: interference in a protein S functional assay

1 reference

12 December 2020

The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects

1 reference

12 December 2020

Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI117458

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31 July 2017

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31 July 2017

1 reference