(Q34189506)

31 July 2017

Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme (English)

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31 July 2017

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Eric J Hayden

1

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31 July 2017

Evandro Ferrada

series ordinal

2

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31 July 2017

Andreas Wagner

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

1 June 2011

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31 July 2017

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31 July 2017

474

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31 July 2017

7349

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31 July 2017

92-95

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https://scigraph.springernature.com/pub.10.1038/nature10083

31 July 2017

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cites work

Uncovering cryptic genetic variation.

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https://api.crossref.org/works/10.1038%2FNATURE10083

From genotype to phenotype: buffering mechanisms and the storage of genetic information

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE10083

Evolutionary potential of hidden genetic variation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Hsp90 as a capacitor for morphological evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

A yeast prion provides a mechanism for genetic variation and phenotypic diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Cryptic genetic variation is enriched for potential adaptations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Exaptation—a Missing Term in the Science of Form

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Protein stability promotes evolvability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Structural evidence for a two-metal-ion mechanism of group I intron splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Assembly of core helices and rapid tertiary folding of a small bacterial group I ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Folding intermediates of a self-splicing RNA: mispairing of the catalytic core

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Evolution in vitro of an RNA enzyme with altered metal dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Thermodynamic effects of formamide on DNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Catalytic promiscuity and the evolution of new enzymatic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

New ligase-derived RNA polymerase ribozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Formation of an active site in trans by interaction of two complete Varkud Satellite ribozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Multidimensional epistasis and the disadvantage of sex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Darwinian evolution can follow only very few mutational paths to fitter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

The population genetic theory of hidden variation and genetic robustness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Assembly PCR oligo maker: a tool for designing oligodeoxynucleotides for constructing long DNA molecules for RNA production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Inventing and improving ribozyme function: rational design versus iterative selection methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

A general method applicable to the search for similarities in the amino acid sequence of two proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Detection of high levels of recombination generated during PCR amplification of RNA templates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE10083

Randomization of genes by PCR mutagenesis

21 January 2018

1 reference

12 December 2020

Directed evolution of an RNA enzyme

1 reference

12 December 2020

DNA polymerase fidelity and the polymerase chain reaction

1 reference

12 December 2020

Activity and thermostability of the small self-splicing group I intron in the pre-tRNA(lle) of the purple bacterium Azoarcus

1 reference

12 December 2020

The 'evolvability' of promiscuous protein functions

1 reference

12 December 2020

Experimental evolution of complexity: in vitro emergence of intermolecular ribozyme interactions

1 reference

12 December 2020

Characterization of the Azoarcus ribozyme: tight binding to guanosine and substrate by an unusually small group I ribozyme

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE10083

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Dimensions Publication ID

31 July 2017

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