(Q34193667)

31 July 2017

title

Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia (English)

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31 July 2017

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J B Rubins

1

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31 July 2017

D Charboneau

2

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31 July 2017

J C Paton

3

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31 July 2017

T J Mitchell

4

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31 July 2017

P W Andrew

5

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31 July 2017

E N Janoff

6

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31 July 2017

language of work or name

English

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publication date

1 January 1995

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Journal of Clinical Investigation

31 July 2017

published in

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31 July 2017

volume

95

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31 July 2017

issue

1

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31 July 2017

page(s)

142-150

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Toxicity of pneumolysin to pulmonary alveolar epithelial cells

31 July 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Identification of hydrogen peroxide as a Streptococcus pneumoniae toxin for rat alveolar epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Binding of cholesterol by sulfhydryl-activated cytolysins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Inhibition of human polymorphonuclear leukocyte respiratory burst, bactericidal activity, and migration by pneumolysin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Effect of immunization with pneumolysin on survival time of mice challenged with Streptococcus pneumoniae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Activation of human complement by the pneumococcal toxin pneumolysin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Characterization of the extracellular bactericidal factors of rat alveolar lining material

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Complement and the host's defense against the pneumococcus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Bacterial growth in vivo. An important determinant of the pulmonary clearance of Diplococcus pneumoniae in rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Pneumococcal bacteremia--no change in mortality in 30 years: analysis of 104 cases and review of the literature

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Effect of Streptococcus pneumoniae on human respiratory epithelium in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Purification and immunogenicity of genetically obtained pneumolysin toxoids and their conjugation to Streptococcus pneumoniae type 19F polysaccharide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Structure and function of pneumolysin, the multifunctional, thiol-activated toxin of Streptococcus pneumoniae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Infections caused by Streptococcus pneumoniae: clinical spectrum, pathogenesis, immunity, and treatment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Toxicity of pneumolysin to pulmonary endothelial cells in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=295392

Anti-pneumolysin activity of commercially available alpha 1-antitrypsin is due to cholesterol impurities

5 July 2018

1 reference

12 December 2020

Effects of aging on antibacterial mechanisms in experimental pneumonia

1 reference

12 December 2020

The role of C5 in polymorphonuclear leukocyte recruitment in response to Streptococcus pneumoniae

1 reference

12 December 2020

Permeability of the mammalian blood-gas barrier and its components

1 reference

12 December 2020

Pneumolysin induces the salient histologic features of pneumococcal infection in the rat lung in vivo

1 reference

12 December 2020

Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein

1 reference

12 December 2020

Comparative efficacy of autolysin and pneumolysin as immunogens protecting mice against infection by Streptococcus pneumoniae

1 reference

12 December 2020

Effect of insertional inactivation of the genes encoding pneumolysin and autolysin on the virulence of Streptococcus pneumoniae type 3

1 reference

12 December 2020

Inhibition of human monocyte respiratory burst, degranulation, phospholipid methylation and bactericidal activity by pneumolysin

1 reference

12 December 2020

Expression of the pneumolysin gene in Escherichia coli: rapid purification and biological properties

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI117631

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31 July 2017

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31 July 2017

1 reference