(Q34194512)

31 July 2017

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title

Role of MED1 (MBD4) Gene in DNA repair and human cancer (English)

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31 July 2017

Bellacosa A

1

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31 July 2017

publication date

1 May 2001

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Journal of Cellular Physiology

31 July 2017

published in

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31 July 2017

volume

187

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31 July 2017

issue

2

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31 July 2017

page(s)

137-144

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Clues to the pathogenesis of familial colorectal cancer

31 July 2017

cites work

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Mismatch repair in correction of replication errors and processing of DNA damage

21 January 2018

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Purification and characterization of Escherichia coli endonuclease III from the cloned nth gene

21 January 2018

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Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.

21 January 2018

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MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

21 January 2018

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A mammalian protein with specific demethylase activity for mCpG DNA.

21 January 2018

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Roles of etheno-DNA adducts in tumorigenicity of olefins

21 January 2018

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A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins

21 January 2018

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The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA.

21 January 2018

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Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

21 January 2018

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Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays

21 January 2018

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Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

21 January 2018

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A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch

21 January 2018

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Identification and characterization of a family of mammalian methyl-CpG binding proteins

21 January 2018

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The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

21 January 2018

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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

21 January 2018

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Replication errors: cha(lle)nging the genome

21 January 2018

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

21 January 2018

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Eukaryotic DNA mismatch repair

21 January 2018

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DNA glycosylases in the base excision repair of DNA

21 January 2018

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Base excision repair of DNA in mammalian cells

21 January 2018

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The role of DNA methylation in cancer genetic and epigenetics

21 January 2018

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Very short patch repair: reducing the cost of cytosine methylation

21 January 2018

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Quality control by DNA repair

21 January 2018

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Significance of multiple mutations in cancer

21 January 2018

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The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)-ethenocytosine from DNA.

21 January 2018

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MutY, an adenine glycosylase active on G-A mispairs, has homology to endonuclease III.

21 January 2018

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Mismatch repair, genetic stability, and cancer

21 January 2018

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Mismatch repair in replication fidelity, genetic recombination, and cancer biology

21 January 2018

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DNA repair mechanisms for the recognition and removal of damaged DNA bases.

21 January 2018

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

21 January 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

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Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase

21 January 2018

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Active repression of methylated genes by the chromosomal protein MBD1

21 January 2018

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Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1

21 January 2018

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Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain

21 January 2018

1 reference

Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase

21 January 2018

1 reference

Purification and cloning of Micrococcus luteus ultraviolet endonuclease, an N-glycosylase/abasic lyase that proceeds via an imino enzyme-DNA intermediate.

21 January 2018

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Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates

21 January 2018

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The DNA repair gene MBD4 (MED1) is mutated in human carcinomas with microsatellite instability

21 January 2018

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3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase

21 January 2018

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Chromosomal localizations and molecular analysis of TDG gene-related sequences

21 January 2018

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Microsatellite instability in cancer of the proximal colon

21 January 2018

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The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?

21 January 2018

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Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

21 January 2018

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The solution structure of the domain from MeCP2 that binds to methylated DNA

21 January 2018

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DNA damages processed by base excision repair: biological consequences

21 January 2018

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Kinetics of the action of thymine DNA glycosylase

21 January 2018

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3-methyladenine DNA glycosylases: structure, function, and biological importance

21 January 2018

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5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.1064

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31 July 2017

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