(Q34200667)

English

Whole exome sequencing in a random sample of North American women with leiomyomas identifies MED12 mutations in majority of uterine leiomyomas

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Whole exome sequencing in a random sample of North American women with leiomyomas identifies MED12 mutations in majority of uterine leiomyomas (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Megan M McGuire

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Alexander Yatsenko

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Lori Hoffner

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Mirka Jones

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Urvashi Surti

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Aleksandar Rajkovic

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

language of work or name

0 references

publication date

12 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

e33251

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

12 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

MED12 exon 2 mutations are common in uterine leiomyomas from South African patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Physiological relevance of cell cycle kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Detection of novel copy number variants in uterine leiomyomas using high-resolution SNP arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

A recurrent mutation in MED12 leading to R961W causes Opitz-Kaveggia syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Novel mutations in FH and expansion of the spectrum of phenotypes expressed in families with hereditary leiomyomatosis and renal cell cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Dynamic regulation of pol II transcription by the mammalian Mediator complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Etiology and pathogenesis of uterine leiomyomas: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Traditional surgical approaches to uterine fibroids: abdominal myomectomy and hysterectomy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

X-chromosome inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Physical mapping of the uterine leiomyoma t(12;14)(q13-15;q24.1) breakpoint on chromosome 14 between SPTB and D14S77.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Trisomy 12 in uterine leiomyomas. A new cytogenetic subgroup

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Uterine leiomyoma cytogenetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

Cytogenetic abnormalities in uterine leiomyomata.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3299761

5 July 2018

The original Lujan syndrome family has a novel missense mutation (p.N1007S) in the MED12 gene

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033251

21 January 2018

MED12 mutations in uterine fibroids--their relationship to cytogenetic subgroups

1 reference

https://pubmed.ncbi.nlm.nih.gov/22428002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent clonal origin of multiple uterine leiomyomas that was determined by X chromosome inactivation and microsatellite analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22428002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The frequency of uterine leiomyomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22428002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal determination of uterine leiomyomas by analyzing differential inactivation of the X-chromosome-linked phosphoglycerokinase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22428002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two discrete regions of deletion at 7q in uterine leiomyomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22428002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of cytogenetic abnormalities in uterine myomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22428002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0033251

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

2012PLoSO...733251M

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

0 references

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