(Q34222494)

31 July 2017

title

Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases (English)

1 reference

31 July 2017

0 references

1 reference

Shamik Das

1

1 reference

31 July 2017

J Allan Tucker

2

1 reference

31 July 2017

Shikha Khullar

3

1 reference

31 July 2017

Rajeev S Samant

4

1 reference

31 July 2017

Lalita A Shevde

5

1 reference

31 July 2017

language of work or name

English

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publication date

29 March 2012

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

3

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31 July 2017

page(s)

e34374

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

29 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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Breast cancer metastasis to the bone: mechanisms of bone loss

5 July 2018

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Hedgehog signaling induced by breast cancer cells promotes osteoclastogenesis and osteolysis

5 July 2018

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Hedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active Site

5 July 2018

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Molecular mediators of macrophage fusion

5 July 2018

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The critical role of the bone microenvironment in cancer metastases

5 July 2018

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The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin

5 July 2018

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Transient overexpression of sonic hedgehog alters the architecture and mechanical properties of trabecular bone

5 July 2018

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5 July 2018

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5 July 2018

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Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function

5 July 2018

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5 July 2018

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The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells

5 July 2018

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Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer

5 July 2018

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Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435

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Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34.

5 July 2018

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5 July 2018

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Hedgehog signaling pathway as a therapeutic target in breast cancer

5 July 2018

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Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer

5 July 2018

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A small molecule antagonist of the alpha(v)beta3 integrin suppresses MDA-MB-435 skeletal metastasis

5 July 2018

1 reference

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Parathyroid hormone-related peptide is required for increased trabecular bone volume in parathyroid hormone-null mice

5 July 2018

1 reference

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A multigenic program mediating breast cancer metastasis to bone

5 July 2018

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Metastasis to bone: causes, consequences and therapeutic opportunities

5 July 2018

1 reference

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Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315536

Osteoblasts induce osteopontin expression in response to attachment on fibronectin: demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315536

Osteopontin involvement in integrin-mediated cell signaling and regulation of expression of alkaline phosphatase during early differentiation of UMR cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315536

Induction of osteogenic differentiation by hedgehog proteins.

5 July 2018

1 reference

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Osteopontin: an interfacial extracellular matrix protein in mineralized tissues

5 July 2018

1 reference

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Expression of collagen, osteocalcin, and bone alkaline phosphatase in a mineralizing rat osteoblastic cell culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315536

Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034374

Breast cancer cells induce osteoblast apoptosis: a possible contributor to bone degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034374

Selective adhesion of osteoblastic cells to different integrin ligands induces osteopontin gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034374

Metastatic breast cancer cells suppress osteoblast adhesion and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034374

Cytokines secreted by bone-metastatic breast cancer cells alter the expression pattern of f-actin and reduce focal adhesion plaques in osteoblasts through PI3K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034374

Expression of Indian Hedgehog signaling molecules in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034374

Hedgehog signaling pathway mediates the progression of non-invasive breast cancer to invasive breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034374

The Hedgehog pathway is a possible therapeutic target for patients with estrogen receptor-negative breast cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315536

Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22479615

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sequential expression of bone matrix proteins during rat calvaria osteoblast differentiation and bone nodule formation in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22479615

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0034374

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference