(Q34228180)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Darryl D D'Lima

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Noboru Taniguchi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Daisuke Seino

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Francisco J Blanco

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Martin Lotz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

publication date

27 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

published in

Arthritis and Rheumatism

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

1182-1192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

Systems biology of the autophagy-lysosomal pathway

15 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Mechanical loading, cartilage degradation, and arthritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Can autophagy promote longevity?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Rapamycin activates autophagy and improves myelination in explant cultures from neuropathic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Posttransplantation therapeutic rapamycin concentration protects nitric oxide-related vascular endothelial function: comparative effects in rat thoracic aorta and coronary endothelial cell culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

mTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Oxidant conditioning protects cartilage from mechanically induced damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Rapamycin protects against rotenone-induced apoptosis through autophagy induction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Mechanical injury and cytokines cause loss of cartilage integrity and upregulate proteins associated with catabolism, immunity, inflammation, and repair

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Autophagy: a new phase in the maturation of growth plate chondrocytes is regulated by HIF, mTOR and AMP kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

The role of TOR in autophagy regulation from yeast to plants and mammals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Huntington's disease: degradation of mutant huntingtin by autophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Autophagy fights disease through cellular self-digestion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Apoptosis and autophagy: regulatory connections between two supposedly different processes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Role of autophagy in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

5 July 2018

Expanding mTOR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Loss of autophagy in the central nervous system causes neurodegeneration in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

TOR signaling in growth and metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Regulation and role of autophagy in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Two ubiquitin-like conjugation systems essential for autophagy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

In vitro model for the study of necrosis and apoptosis in native cartilage.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Biosynthetic response and mechanical properties of articular cartilage after injurious compression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288456

Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro: Interaction with exogenous cytokines

5 July 2018

1 reference

Age- and site-associated biomechanical weakening of human articular cartilage of the femoral condyle

21 January 2018

1 reference

Human chondrocyte apoptosis in response to mechanical injury

21 January 2018

1 reference

The effect of glycosaminoglycan loss on chondrocyte viability: a study on porcine cartilage explants

21 January 2018

1 reference

The extent of matrix damage and chondrocyte death in mechanically traumatized articular cartilage explants depends on rate of loading

21 January 2018

1 reference

Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice

21 January 2018

1 reference

Differential effects of tumor necrosis factor-alpha and interleukin-1beta on cell death in human articular chondrocytes.

21 January 2018

1 reference

Autophagosomes in GFP-LC3 Transgenic Mice.

21 January 2018

1 reference

Differential modulation of the cytokine-induced MMP-9/TIMP-1 protease-antiprotease system by the mTOR inhibitor rapamycin.

21 January 2018

1 reference

Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage

21 January 2018

1 reference

12 December 2020

Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction

1 reference

12 December 2020

Impact of mechanical trauma on matrix and cells

1 reference

12 December 2020

Chondrocyte death by apoptosis is associated with cartilage matrix degradation

1 reference

12 December 2020

Identifiers

DOI

10.1002/ART.33444

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22034068%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

22034068

1 reference