(Q34233389)

31 July 2017

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title

Sphingosine 1-phosphate: synthesis and release (English)

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31 July 2017

main subject

sphingosine 1-phosphate

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ChEBI release 2020-05-28

Yatomi Y

1

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31 July 2017

Ozaki Y

series ordinal

2

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31 July 2017

Ohmori T

series ordinal

3

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31 July 2017

Igarashi Y

series ordinal

4

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31 July 2017

publication date

1 April 2001

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Prostaglandins and Other Lipid Mediators

31 July 2017

published in

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31 July 2017

volume

64

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31 July 2017

issue

1-4

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31 July 2017

page(s)

107-122

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Sphingosine 1-phosphate: a prototype of a new class of second messengers.

31 July 2017

cites work

1 reference

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7 January 2021

Bioactive lysophospholipids and their G protein-coupled receptors

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7 January 2021

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate.

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7 January 2021

Functional roles of sphingosine, sphingosine 1-phosphate, and methylsphingosines: in regard to membrane sphingolipid signaling pathways

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7 January 2021

Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

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7 January 2021

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

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7 January 2021

Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1-phosphate

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7 January 2021

Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism

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7 January 2021

Purification and characterization of rat kidney sphingosine kinase

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7 January 2021

Molecular cloning and functional characterization of murine sphingosine kinase

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7 January 2021

Evidence for the presence of multiple forms of Sph kinase in human platelets

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7 January 2021

The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases

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7 January 2021

The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase

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7 January 2021

Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast

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7 January 2021

Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.

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7 January 2021

Phosphatidate phosphohydrolase catalyzes the hydrolysis of ceramide 1-phosphate, lysophosphatidate, and sphingosine 1-phosphate

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7 January 2021

Cloning and characterization of two human isozymes of Mg2+-independent phosphatidic acid phosphatase

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7 January 2021

Mammalian lipid phosphate phosphohydrolases

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7 January 2021

Calcium mobilization via sphingosine kinase in signalling by the Fc epsilon RI antigen receptor

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7 January 2021

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors

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7 January 2021

Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase

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7 January 2021

Functions of ceramide in coordinating cellular responses to stress

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7 January 2021

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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7 January 2021

N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Sphingosine 1-phosphate formation and intracellular Ca2+ mobilization in human platelets: evaluation with sphingosine kinase inhibitors

1 reference

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7 January 2021

Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

1 reference

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7 January 2021

Sphingosine Kinase in Blood Platelets

1 reference

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7 January 2021

Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Properties and specificities of sphingosine kinase from blood platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Effect of acidic phospholipids on sphingosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Molecular mechanisms of platelet activation

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

The bioactive phospholipid lysophosphatidic acid is released from activated platelets.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Quantitative measurement of sphingosine 1-phosphate in biological samples by acylation with radioactive acetic anhydride

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells

1 reference

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7 January 2021

Malignant effusions contain lysophosphatidic acid (LPA)-like activity

1 reference

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7 January 2021

Metabolism and functional effects of sphingolipids in blood cells

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7 January 2021

Sphingosine 1-phosphate regulates melanoma cell motility through a receptor-coupled extracellular action and in a pertussis toxin-insensitive manner

1 reference

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7 January 2021

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

1 reference

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7 January 2021

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1 reference

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7 January 2021

Flip-flop: the transmembrane translocation of lipids

1 reference

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7 January 2021

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

1 reference

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7 January 2021

Differential energy requirements for platelet responses. A simultaneous study of aggregation, three secretory processes, arachidonate liberation, phosphatidylinositol breakdown and phosphatidate production

1 reference

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7 January 2021

Quantification of energy consumption in platelets during thrombin-induced aggregation and secretion. Tight coupling between platelet responses and the increment in energy consumption

1 reference

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7 January 2021

Identification of lysophospholipid receptors in human platelets: the relation of two agonists, lysophosphatidic acid and sphingosine 1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Structure−Activity Analysis of the Effects of Lysophosphatidic Acid on Platelet Aggregation†

1 reference

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7 January 2021

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells

1 reference

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7 January 2021

Sphingosine 1-phosphate stimulates tyrosine phosphorylation of focal adhesion kinase and chemotactic motility of endothelial cells via the G(i) protein-linked phospholipase C pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Rho-mediated phosphorylation of focal adhesion kinase and myosin light chain in human endothelial cells stimulated with sphingosine 1-phosphate, a bioactive lysophospholipid released from activated platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibitio

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Flow-mediated endothelial mechanotransduction

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Cloning of cDNAs encoding G protein-coupled receptor expressed in human endothelial cells exposed to fluid shear stress

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Molecular cloning of a novel putative G protein-coupled receptor expressed in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Comparison of intrinsic activities of the putative sphingosine 1-phosphate receptor subtypes to regulate several signaling pathways in their cDNA-transfected Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

Sphingosine 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart

1 reference

https://api.crossref.org/works/10.1016%2FS0090-6980%2801%2900103-4

7 January 2021

10.1016/S0090-6980(01)00103-4

Identifiers

DOI

1 reference

release_usopxoc4ynhtfj4fagxdih5z3q

31 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/usopxoc4ynhtfj4fagxdih5z3q

24 November 2022

mapped directly with Wikidata item

1 reference