(Q34234465)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22101547%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions (English)

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17 January 2020

1

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17 January 2020

Michaël R. Laurent

2

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17 January 2020

Frank Claessens

5

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17 January 2020

author name string

Steven Boonen

3

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17 January 2020

Dirk Vanderschueren

4

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17 January 2020

publication date

19 November 2011

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Cellular and Molecular Life Sciences

17 January 2020

published in

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17 January 2020

volume

69

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17 January 2020

issue

10

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17 January 2020

page(s)

1651-1667

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Androgen-independent induction of prostate-specific antigen gene expression via cross-talk between the androgen receptor and protein kinase A signal transduction pathways

17 January 2020

cites work

1 reference

12 December 2020

Effects of a novel selective androgen receptor modulator on dexamethasone-induced and hypogonadism-induced muscle atrophy.

1 reference

12 December 2020

Dihydrotestosterone activates the MAPK pathway and modulates maximum isometric force through the EGF receptor in isolated intact mouse skeletal muscle fibres

1 reference

12 December 2020

Essential role for Dicer during skeletal muscle development.

1 reference

12 December 2020

Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy

1 reference

12 December 2020

Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistance

1 reference

12 December 2020

Actin associated proteins function as androgen receptor coregulators: an implication of androgen receptor's roles in skeletal muscle

1 reference

12 December 2020

IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1.

1 reference

12 December 2020

Transforming Growth Factor type beta and Smad family signaling in stem cell function

1 reference

12 December 2020

Functional testosterone receptors in plasma membranes of T cells.

1 reference

12 December 2020

Plasma and Muscle Polyamine Levels in Aerobically Exercised Rats Treated with Salbutamol

1 reference

12 December 2020

Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells

1 reference

12 December 2020

Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle

1 reference

12 December 2020

Effect of trenbolone acetate on protein synthesis and degradation rates in fused bovine satellite cell cultures.

1 reference

12 December 2020

The IGF-I signaling pathway

1 reference

12 December 2020

Interactions of sex hormone-binding globulin with target cells

1 reference

12 December 2020

Regulation of skeletal myogenesis by Notch

1 reference

12 December 2020

Skeletal muscle satellite cells are committed to myogenesis and do not spontaneously adopt nonmyogenic fates

1 reference

12 December 2020

Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor

1 reference

12 December 2020

Rapid actions of steroid receptors in cellular signaling pathways.

1 reference

12 December 2020

Regulation of terminal Schwann cell number at the adult neuromuscular junction.

1 reference

12 December 2020

Effects of testosterone supplementation on skeletal muscle fiber hypertrophy and satellite cells in community-dwelling older men.

1 reference

12 December 2020

Direct isolation of satellite cells for skeletal muscle regeneration.

1 reference

12 December 2020

Impaired skeletal muscle development and function in male, but not female, genomic androgen receptor knockout mice.

1 reference

12 December 2020

Myostatin negatively regulates satellite cell activation and self-renewal

1 reference

12 December 2020

Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis

1 reference

12 December 2020

Skeletal muscle hypertrophy and atrophy signaling pathways

1 reference

12 December 2020

A Direct Effect of Testosterone on Muscle Cells in Tissue Culture1

1 reference

12 December 2020

Androgen-stimulated pubertal growth: the effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty

1 reference

12 December 2020

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

1 reference

12 December 2020

Neonatal androgen maintains sexually dimorphic muscles in the absence of innervation

1 reference

12 December 2020

Testosterone administration to older men improves muscle function: molecular and physiological mechanisms

1 reference

12 December 2020

Growth factors and muscle ageing.

1 reference

12 December 2020

Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit

1 reference

12 December 2020

Androgen locally regulates rat bulbocavernosus and levator ani size

1 reference

12 December 2020

A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation

1 reference

12 December 2020

Androgen receptor expression during C2C12 skeletal muscle cell line differentiation

1 reference

12 December 2020

Testosterone dose-response relationships in healthy young men.

1 reference

12 December 2020

Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells

1 reference

12 December 2020

Testosterone-induced masculinization of the rat levator ani muscle during puberty

1 reference

12 December 2020

Steroidal androgens and nonsteroidal, tissue-selective androgen receptor modulator, S-22, regulate androgen receptor function through distinct genomic and nongenomic signaling pathways.

1 reference

12 December 2020

Diverse roles of androgen receptor (AR) domains in AR-mediated signaling

1 reference

12 December 2020

Breakthrough in cachexia treatment through a novel selective androgen receptor modulator?!

1 reference

12 December 2020

Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation

1 reference

12 December 2020

The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis.

1 reference

12 December 2020

Proliferation of skeletal muscle satellite cells after castration and administration of testosterone propionate

1 reference

12 December 2020

Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity

1 reference

12 December 2020

Myocyte androgen receptors increase metabolic rate and improve body composition by reducing fat mass.

1 reference

12 December 2020

Testosterone action on skeletal muscle

1 reference

12 December 2020

Transcription of muscle-specific genes is repressed by reactivation of pp60v-src in postmitotic quail myotubes

1 reference

12 December 2020

Androgenic regulation of androgen receptor immunoreactivity in motoneurons of the spinal nucleus of the bulbocavernosus of male rats

1 reference

12 December 2020

A direct beta-catenin-independent interaction between androgen receptor and T cell factor 4

1 reference

12 December 2020

Myostatin is an inhibitor of myogenic differentiation.

1 reference

12 December 2020

Edward F. Adolph distinguished lecture: muscle as an endocrine organ: IL-6 and other myokines

1 reference

12 December 2020

Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement

1 reference

12 December 2020

Myostatin Knockout in Mice Increases Myogenesis and Decreases Adipogenesis

1 reference

12 December 2020

MicroRNAs flex their muscles

1 reference

12 December 2020

Interaction of sex hormone-binding globulin with plasma membranes from the rat epididymis and other tissues

1 reference

12 December 2020

Androgens negatively regulate myostatin expression in an androgen-dependent skeletal muscle

1 reference

12 December 2020

The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

1 reference

12 December 2020

Androgen receptor immunoreactivity in skeletal muscle: enrichment at the neuromuscular junction

1 reference

12 December 2020

Testosterone-induced increase in muscle size in healthy young men is associated with muscle fiber hypertrophy

1 reference

12 December 2020

Stimulation of prostate cancer growth by androgens and estrogens through the intermediacy of sex hormone-binding globulin

1 reference

12 December 2020

Testosterone-induced muscle hypertrophy is associated with an increase in satellite cell number in healthy, young men.

1 reference

12 December 2020

Testosterone signaling through internalizable surface receptors in androgen receptor-free macrophages

1 reference

12 December 2020

Satellite cell proliferation and increase in the number of myonuclei induced by testosterone in the levator ani muscle of the adult female rat

1 reference

12 December 2020

The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny

1 reference

12 December 2020

The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.

1 reference

12 December 2020

Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells

1 reference

12 December 2020

The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men.

1 reference

12 December 2020

From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

1 reference

12 December 2020

Skeletal sexual dimorphism: relative contribution of sex steroids, GH–IGF1, and mechanical loading

1 reference

12 December 2020

Cellular and molecular regulation of muscle regeneration

1 reference

12 December 2020

No change in skeletal muscle satellite cells in young and aging rat soleus muscle

1 reference

12 December 2020

Oral testosterone supplementation increases muscle and decreases fat mass in healthy elderly males with low-normal gonadal status

1 reference

12 December 2020

Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle

1 reference

12 December 2020

Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways

1 reference

12 December 2020

MicroRNAs are mediators of androgen action in prostate and muscle

1 reference

12 December 2020

Nitric oxide and repair of skeletal muscle injury

1 reference

12 December 2020

Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men.

1 reference

12 December 2020

A three-dimensional view of the molecular machinery of RNA interference

1 reference

12 December 2020

Notch and Wnt signaling, physiological stimuli and postnatal myogenesis

1 reference

12 December 2020

Skeletal muscle-derived CD34+/45- and CD34-/45- stem cells are situated hierarchically upstream of Pax7+ cells.

1 reference

12 December 2020

MicroRNA control of muscle development and disease

1 reference

12 December 2020

Growth factors signal to steroid receptors through mitogen-activated protein kinase regulation of p160 coactivator activity

1 reference

12 December 2020

Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin.

1 reference

12 December 2020

Growth hormone and the insulin-like growth factor system in myogenesis

1 reference

12 December 2020

Androgen receptor in human skeletal muscle and cultured muscle satellite cells: up-regulation by androgen treatment.

1 reference

12 December 2020

Regulation of insulin-like growth factor-I in skeletal muscle and muscle cells

1 reference

12 December 2020

C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression

1 reference

12 December 2020

Unraveling androgen action in muscle: genetic tools probing cellular mechanisms

1 reference

12 December 2020

Myostatin signals through Pax7 to regulate satellite cell self-renewal

1 reference

12 December 2020

The skeletal muscle satellite cell: the stem cell that came in from the cold.

1 reference

12 December 2020

Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex

1 reference

12 December 2020

Skeletal myogenic progenitors originating from embryonic dorsal aorta coexpress endothelial and myogenic markers and contribute to postnatal muscle growth and regeneration

1 reference

12 December 2020

Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin

1 reference

12 December 2020

Testosterone injection stimulates net protein synthesis but not tissue amino acid transport

1 reference

12 December 2020

Role of IGF-I and IGF-binding proteins within diaphragm muscle in modulating the effects of nandrolone

1 reference

12 December 2020

Identification and characterization of a non-satellite cell muscle resident progenitor during postnatal development

1 reference

12 December 2020

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

12 December 2020

Double muscling in cattle due to mutations in the myostatin gene

1 reference

12 December 2020

Notch-mediated restoration of regenerative potential to aged muscle

1 reference

12 December 2020

Muscle-derived stem cells

1 reference

12 December 2020

Lower skeletal muscle mass in male transgenic mice with muscle-specific overexpression of myostatin

1 reference

12 December 2020

Further characterisation of the molecular signature of quiescent and activated mouse muscle satellite cells

1 reference

12 December 2020

Follistatin complexes Myostatin and antagonises Myostatin-mediated inhibition of myogenesis

1 reference

12 December 2020

Sex hormone-binding globulin: not only a transport protein. What news is around the corner?

1 reference

12 December 2020

Influence of physical exercise on polyamine synthesis in the rat skeletal muscle

1 reference

12 December 2020

The serum transport of steroid hormones

1 reference

12 December 2020

Linking ligand-induced alterations in androgen receptor structure to differential gene expression: a first step in the rational design of selective androgen receptor modulators

1 reference

12 December 2020

The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial.

1 reference

12 December 2020

Myostatin inhibits cell proliferation and protein synthesis in C2C12 muscle cells

1 reference

12 December 2020

Biological progression from adult bone marrow to mononucleate muscle stem cell to multinucleate muscle fiber in response to injury.

1 reference

12 December 2020

Ageing of human muscles and tendons

1 reference

12 December 2020

Testosterone and oxandrolone, a nonaromatizable androgen, specifically amplify the mass and rate of growth hormone (GH) secreted per burst without altering GH secretory burst duration or frequency or the GH half-life

1 reference

12 December 2020

Identification of androgen response elements in the insulin-like growth factor I upstream promoter

1 reference

12 December 2020

The role of stem cells in skeletal and cardiac muscle repair

1 reference

12 December 2020

Phosphatidylinositol 3-kinase and p70 s6 kinase participate in the regulation of protein turnover in skeletal muscle by insulin and insulin-like growth factor I

1 reference

12 December 2020

Regulation of myogenic differentiation by androgens: cross talk between androgen receptor/ beta-catenin and follistatin/transforming growth factor-beta signaling pathways

1 reference

12 December 2020

Age-associated changes in the response of skeletal muscle cells to exercise and regeneration

1 reference

12 December 2020

Generation and analysis of an androgen-responsive myoblast cell line indicates that androgens regulate myotube protein accretion

1 reference

12 December 2020

The role of GH and IGF-I in mediating anabolic effects of testosterone on androgen-responsive muscle

1 reference

12 December 2020

Differential anabolic effects of testosterone and amino acid feeding in older men.

1 reference

12 December 2020

Testosterone up-regulates androgen receptors and decreases differentiation of porcine myogenic satellite cells in vitro

1 reference

12 December 2020

Phosphorylation of p70s6 kinase is implicated in androgen-induced levator ani muscle anabolism in castrated rats

1 reference

12 December 2020

Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy

1 reference

12 December 2020

Sexual dimorphism and androgen regulation of satellite cell population in differentiating rat levator ani muscle

1 reference

12 December 2020

Myogenic specification of side population cells in skeletal muscle

1 reference

12 December 2020

Insulin-like growth factor-I-induced androgen receptor activation is mediated by the PI3K/Akt pathway in C2C12 skeletal muscle cells

1 reference

12 December 2020

Pharmacodynamics of selective androgen receptor modulators

1 reference

12 December 2020

Late onset of obesity in male androgen receptor-deficient (AR KO) mice

1 reference

12 December 2020

Insulin-like growth factor-I induces androgen receptor activation in differentiating C2C12 skeletal muscle cells

1 reference

12 December 2020

Early postnatal response of the spinal nucleus of the bulbocavernosus and target muscles to testosterone in male gerbils

1 reference

12 December 2020

Androgen-induced regrowth in the castrated rat ventral prostate: role of 5alpha-reductase

1 reference

12 December 2020

Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

Long-term castration effects motoneuron size but not number in the spinal nucleus of the bulbocavernosus in the adult male Mongolian gerbil

1 reference

12 December 2020

Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells

1 reference

12 December 2020

Short-term oxandrolone administration stimulates net muscle protein synthesis in young men.

1 reference

12 December 2020

Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity

1 reference

12 December 2020

Physical activity in the androgen receptor knockout mouse: evidence for reversal of androgen deficiency on cancellous bone.

1 reference

12 December 2020

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

1 reference

12 December 2020

Mechanisms of Ca(2+)-dependent transcription

1 reference

12 December 2020

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

1 reference

12 December 2020

Myocytic androgen receptor controls the strength but not the mass of limb muscles

1 reference

12 December 2020

Aldosterone- and testosterone-mediated intracellular calcium response in skeletal muscle cell cultures

1 reference

12 December 2020

Myostatin inhibits myoblast differentiation by down-regulating MyoD expression.

1 reference

12 December 2020

Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation

1 reference

12 December 2020

The human prostate cancer cell line LNCaP bears functional membrane testosterone receptors that increase PSA secretion and modify actin cytoskeleton

1 reference

12 December 2020

Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

1 reference

12 December 2020

Mouse model of testosterone-induced muscle fiber hypertrophy: involvement of p38 mitogen-activated protein kinase-mediated Notch signaling

1 reference

12 December 2020

Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway

1 reference

12 December 2020

p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step

1 reference

12 December 2020

Research Resource: The androgen receptor modulates expression of genes with critical roles in muscle development and function

1 reference

12 December 2020

Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation

1 reference

12 December 2020

Muscle regeneration in the prolonged absence of myostatin

1 reference

12 December 2020

Recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene

1 reference

12 December 2020

The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum

1 reference

12 December 2020

Control of myogenic differentiation by cellular oncogenes

1 reference

12 December 2020

Inhibition of myostatin in adult mice increases skeletal muscle mass and strength

1 reference

12 December 2020

Effects of dexamethasone and anabolic agents on proliferation and protein synthesis and degradation in C2C12 myogenic cells

1 reference

12 December 2020

Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of {beta}-catenin

1 reference

12 December 2020

A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs

1 reference

12 December 2020

IGF-I mRNA levels in bovine satellite cell cultures: effects of fusion and anabolic steroid treatment

1 reference

12 December 2020

Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation

1 reference

12 December 2020

Polyamines: mysterious modulators of cellular functions

1 reference

12 December 2020

Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses

1 reference

12 December 2020

Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels

1 reference

12 December 2020

Suppression of body fat accumulation in myostatin-deficient mice

1 reference

12 December 2020

Sex hormones and frailty in older men: the osteoporotic fractures in men (MrOS) study

1 reference

12 December 2020

Preferential enhancement of myoblast differentiation by insulin-like growth factors (IGF I and IGF II) in primary cultures of chicken embryonic cells

1 reference

12 December 2020

Androgen effects on body composition

1 reference

12 December 2020

Cellular and molecular basis of age-related sarcopenia.

1 reference

12 December 2020

Effect of the beta-adrenoceptor agonist clenbuterol and phytohaemagglutinin on growth, protein synthesis and polyamine metabolism of tissues of the rat

1 reference

12 December 2020

Specific, nongenomic actions of steroid hormones

1 reference

12 December 2020

Purification and cell-surface marker characterization of quiescent satellite cells from murine skeletal muscle by a novel monoclonal antibody.

1 reference

12 December 2020

Longitudinal changes in body composition in older men and women: role of body weight change and physical activity

1 reference

12 December 2020

Trenbolone enhances myogenic differentiation by enhancing β-catenin signaling in muscle-derived stem cells of cattle

1 reference

12 December 2020

Characterization of 5'-regulatory region of human myostatin gene: regulation by dexamethasone in vitro

1 reference

12 December 2020

Satellite cell of skeletal muscle fibers

1 reference

12 December 2020

Activation of the human androgen receptor through a protein kinase A signaling pathway

1 reference

12 December 2020

Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging

1 reference

12 December 2020

Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation

1 reference

12 December 2020

Comparison of androgen regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase gene expression in rodent kidney and accessory sex organs

1 reference

12 December 2020

Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line

1 reference

12 December 2020

Notch1 is an effector of Akt and hypoxia in melanoma development

1 reference

12 December 2020

Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism.

1 reference

12 December 2020

Body composition and metabolic profile in women with complete androgen insensitivity syndrome

1 reference

12 December 2020

Changes in muscle mass, muscle strength, and power but not physical function are related to testosterone dose in healthy older men.

1 reference

12 December 2020

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene

1 reference

12 December 2020

Androgen regulation of satellite cell function

1 reference

12 December 2020

Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha.

1 reference

12 December 2020

Androgen signaling in myocytes contributes to the maintenance of muscle mass and fiber type regulation but not to muscle strength or fatigue.

1 reference

12 December 2020

Androgen receptor expression in the levator ani muscle of male mice

1 reference

12 December 2020